quinacrine has been researched along with Leukemia, Monocytic, Acute in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Leukemia, Monocytic, Acute: An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 16 treated patients with acute myelogenous leukemia and a normal karyotype, 11 (69 per cent) had a complete remission and a median survival of 13 months." | 1.26 | Correlation of clinical findings with quinacrine-banded chromosomes in 90 adults with acute nonlymphocytic leukemia: an eight-year study (1970-1977). ( Golomb, HM; Mintz, U; Rowley, JD; Testa, JR; Vardiman, JW, 1978) |
| "Macrothrombocytosis was observed in most of the cases of AML, was rare in AGL and was never found in ALL." | 1.26 | Platelet volume, density and 5 HT organelles (mepacrine test) in acute leukaemia. ( Boneu, B; Capdeville, J; Caranobe, C; Nouvel, C; Pris, J; Sie, P, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golomb, HM | 1 |
| Vardiman, JW | 1 |
| Rowley, JD | 1 |
| Testa, JR | 1 |
| Mintz, U | 1 |
| Nouvel, C | 1 |
| Caranobe, C | 1 |
| Sie, P | 1 |
| Capdeville, J | 1 |
| Pris, J | 1 |
| Boneu, B | 1 |
2 other studies available for quinacrine and Leukemia, Monocytic, Acute
| Article | Year |
|---|---|
Correlation of clinical findings with quinacrine-banded chromosomes in 90 adults with acute nonlymphocytic leukemia: an eight-year study (1970-1977).
Topics: Adolescent; Adult; Aged; Chromosome Aberrations; Female; Humans; Leukemia, Monocytic, Acute; Leukemi | 1978 |
Platelet volume, density and 5 HT organelles (mepacrine test) in acute leukaemia.
Topics: Blood Cell Count; Blood Platelets; Cytoplasmic Granules; Humans; Leukemia; Leukemia, Lymphoid; Leuke | 1978 |