quinacrine has been researched along with Klinefelter Syndrome in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Walker, S | 1 |
Gregson, NM | 1 |
Hibbard, BM | 1 |
Dallapiccola, B | 1 |
Bobrow, M | 1 |
Pearson, PL | 1 |
Pike, MC | 1 |
el-Alfi, OS | 1 |
Polani, PE | 1 |
Mutton, DE | 1 |
4 other studies available for quinacrine and Klinefelter Syndrome
Article | Year |
---|---|
Nuclear sex and antenatal diagnosis of Klinefelter's syndrome.
Topics: Adult; Amniocentesis; Autoradiography; Female; Fetal Diseases; Fluorescence; Gestational Age; Humans | 1971 |
Identification of the human sex chromosome complement in polymorphonuclear leukocytes: a new technique.
Topics: Female; Humans; Klinefelter Syndrome; Leukocytes; Male; Methods; Quinacrine; Sex Chromatin; Sex Chro | 1971 |
Length variation in the quinacrine-binding segment of human Y chromosomes of different sizes.
Topics: Chromatin; Fluorescence; Genetic Variation; Humans; Infertility, Male; Klinefelter Syndrome; Male; Q | 1971 |
Y-fluorescence of interphase nuclei, especially circulating lymphocytes.
Topics: Amniotic Fluid; Female; Fetus; Fibroblasts; Fluorescence; Humans; Klinefelter Syndrome; Lymphocytes; | 1971 |