quinacrine has been researched along with Kidney Diseases in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Renal toxicity is a serious side effect that hinders the use of cisplatin, a commonly used and effective chemotherapeutic agent." | 1.62 | Quinacrine Ameliorates Cisplatin-Induced Renal Toxicity via Modulation of Sirtuin-1 Pathway. ( Abo El-Magd, NF; Ebrahim, HA; Eisa, NH; El-Sherbiny, M, 2021) |
| "Quinacrine treatment significantly protected animals against CsA induced biochemical changes." | 1.29 | Quinacrine attenuates cyclosporine-induced nephrotoxicity in rats. ( al Khader, A; al Sulaiman, M; Kishore, PN; Morais, C; Tariq, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abo El-Magd, NF | 1 |
| Ebrahim, HA | 1 |
| El-Sherbiny, M | 1 |
| Eisa, NH | 1 |
| CARAZO, A | 1 |
| EISEMAN, B | 1 |
| Wallace, DJ | 1 |
| al Khader, A | 1 |
| al Sulaiman, M | 1 |
| Kishore, PN | 1 |
| Morais, C | 1 |
| Tariq, M | 1 |
1 review available for quinacrine and Kidney Diseases
| Article | Year |
|---|---|
Antimalarial agents and lupus.
Topics: Antibodies, Antiphospholipid; Antimalarials; Chloroquine; Female; Humans; Hydroxychloroquine; Kidney | 1994 |
3 other studies available for quinacrine and Kidney Diseases
| Article | Year |
|---|---|
Quinacrine Ameliorates Cisplatin-Induced Renal Toxicity via Modulation of Sirtuin-1 Pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Disease Models, Animal; Fibrosis; Immunohistoc | 2021 |
ROLE OF AMMONIA IN ISCHEMIC RENAL DAMAGE; EFFECT OF ATABRINE ON AMMONIA PRODUCTION.
Topics: Ammonia; Blood Chemical Analysis; Blood Pressure; Creatine; Creatinine; Dogs; Ischemia; Kidney; Kidn | 1965 |
Quinacrine attenuates cyclosporine-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Electrolytes; Free Radicals; Glutathione; Kidney; Kidney Diseases | 1996 |