quinacrine has been researched along with Injury, Ischemia-Reperfusion in 10 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the influence of quinacrine, which is an inhibitor of phospholipase A2, on gut-origin bacteria/endotoxin translocation in rats with gut ischemia/reperfusion injury." | 7.71 | [Effects of quinacrine on gut-origin bacteria/endotoxin translocation in rats with gut ischemia/reperfusion injury]. ( Chen, J; Tu, W; Xiao, G, 2001) |
| "To explore the influence of quinacrine, which is an inhibitor of phospholipase A2, on gut-origin bacteria/endotoxin translocation in rats with gut ischemia/reperfusion injury." | 3.71 | [Effects of quinacrine on gut-origin bacteria/endotoxin translocation in rats with gut ischemia/reperfusion injury]. ( Chen, J; Tu, W; Xiao, G, 2001) |
| " Pretreatment with a nonspecific phospholipase A2 inhibitor (methylprednisolone, dexamethasone, or quinacrine) was ineffective in diminishing the reperfusion injury in either case." | 3.68 | Reperfusion mucosal damage after complete intestinal ischemia in the dog: the effects of antioxidant and phospholipase A2 inhibitor therapy. ( Boros, M; Karácsony, G; Kaszaki, J; Nagy, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (80.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pfaff, MJ | 1 |
| Mukhopadhyay, S | 1 |
| Hoofnagle, M | 1 |
| Chabasse, C | 1 |
| Sarkar, R | 1 |
| Shen, CY | 1 |
| Wang, D | 1 |
| Chang, ML | 1 |
| Hsu, K | 1 |
| Koike, K | 1 |
| Moore, EE | 1 |
| Moore, FA | 1 |
| Kim, FJ | 1 |
| Carl, VS | 1 |
| Banerjee, A | 1 |
| Boros, M | 1 |
| Karácsony, G | 1 |
| Kaszaki, J | 1 |
| Nagy, S | 1 |
| Mcanulty, JF | 4 |
| Huang, XQ | 1 |
| Waller, K | 1 |
| Tu, W | 1 |
| Chen, J | 1 |
| Xiao, G | 1 |
| Das, DK | 1 |
| Iyengar, J | 1 |
| Jones, RM | 1 |
| Lu, D | 1 |
| Maity, S | 1 |
10 other studies available for quinacrine and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Tumor suppressor protein p53 negatively regulates ischemia-induced angiogenesis and arteriogenesis.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Benzothiazoles; Blood Flow Velocity; | 2018 |
Protective effect of mepacrine on hypoxia-reoxygenation-induced acute lung injury in rats.
Topics: Animals; Capillary Permeability; Dexamethasone; Granulocytes; Hypoxia; In Vitro Techniques; Leukocyt | 1995 |
Gut phospholipase A2 mediates neutrophil priming and lung injury after mesenteric ischemia-reperfusion.
Topics: Animals; Enzyme Activation; Intestines; Ischemia; Kinetics; Lung Diseases; Male; N-Formylmethionine | 1995 |
Reperfusion mucosal damage after complete intestinal ischemia in the dog: the effects of antioxidant and phospholipase A2 inhibitor therapy.
Topics: Allopurinol; Animals; Antioxidants; Dexamethasone; Dogs; Female; Ileum; Intestinal Mucosa; Ischemia; | 1993 |
Nonesterified fatty acid content of rabbit kidney cortex slices after warm ischemia and low temperature preservation.
Topics: Animals; Evaluation Studies as Topic; Fatty Acids, Nonesterified; In Vitro Techniques; Ischemia; Kid | 1996 |
A role for the mitochondrial permeability transition pore in ex vivo hypothermic resuscitation of warm ischemic kidney tissue.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Calcium; Glutathione; In Vitro Techniques; | 1997 |
The effect of calcium on hypothermia-facilitated resuscitation of warm ischemic kidney tissue slices: a role for the mitochondrial permeability transition pore?
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Calcium; Cold Temperature; Cyclosporine; Fatty Acids, N | 1998 |
The effect of quinacrine on oxidative stress in kidney tissue stored at low temperature after warm ischemic injury.
Topics: Animals; Cattle; Cold Temperature; In Vitro Techniques; Kidney; Lipid Peroxidation; Male; Malondiald | 1999 |
[Effects of quinacrine on gut-origin bacteria/endotoxin translocation in rats with gut ischemia/reperfusion injury].
Topics: Animals; Bacterial Translocation; Digestive System; Endotoxins; Female; Kidney; Liver; Lung; Lymph N | 2001 |
Protection from nonfreezing cold injury by quinacrine, a phospholipase inhibitor.
Topics: Animals; Body Temperature; Cold Temperature; Fatty Acids; Free Radicals; Hemodynamics; Leg; Lipid Pe | 1991 |