quinacrine has been researched along with Hemorrhagic Shock in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hemorrhagic shock was obtained by bleeding into a reservoir for 15 min or 1 h." | 5.26 | Juxtaglomerular cell activity during hemorrhage and ischemia as revealed by quinacrine histofluorescence. ( Alund, M, 1980) |
| "Our previous work identified posthemorrhagic shock mesenteric lymph (PHSML) lipids as key elements in polymorphonuclear neutrophil (PMN)--provoked acute lung injury." | 1.31 | Phospholipase A(2)--derived neutral lipids from posthemorrhagic shock mesenteric lymph prime the neutrophil oxidative burst. ( Biffl, WL; Ciesla, DJ; Gonzalez, RJ; Moore, EE; Offner, PJ; Silliman, CC, 2001) |
| "Previous work links post-hemorrhagic shock mesenteric lymph (PHSML) lipids and neutrophil (PMN) priming in the pathogenesis of ARDS." | 1.31 | Post-hemorrhagic shock mesenteric lymph lipids prime neutrophils for enhanced cytotoxicity via phospholipase A2. ( Biffl, WL; Ciesla, DJ; Gonzalez, RJ; Meng, X; Moore, EE; Silliman, CC, 2001) |
| "The mechanism by which hemorrhagic shock injures the gut and leads to the translocation of bacteria remains incompletely determined." | 1.29 | Calcium and phospholipase A2 appear to be involved in the pathogenesis of hemorrhagic shock-induced mucosal injury and bacterial translocation. ( Deitch, EA; Lu, Q; Xu, D, 1995) |
| "Hemorrhagic shock was obtained by bleeding into a reservoir for 15 min or 1 h." | 1.26 | Juxtaglomerular cell activity during hemorrhage and ischemia as revealed by quinacrine histofluorescence. ( Alund, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alund, M | 1 |
| Xu, D | 1 |
| Lu, Q | 1 |
| Deitch, EA | 1 |
| Gonzalez, RJ | 2 |
| Moore, EE | 2 |
| Ciesla, DJ | 2 |
| Biffl, WL | 2 |
| Offner, PJ | 1 |
| Silliman, CC | 2 |
| Meng, X | 1 |
4 other studies available for quinacrine and Hemorrhagic Shock
| Article | Year |
|---|---|
Juxtaglomerular cell activity during hemorrhage and ischemia as revealed by quinacrine histofluorescence.
Topics: Animals; Carbon Radioisotopes; Cytoplasmic Granules; Ischemia; Juxtaglomerular Apparatus; Kidney; Ma | 1980 |
Calcium and phospholipase A2 appear to be involved in the pathogenesis of hemorrhagic shock-induced mucosal injury and bacterial translocation.
Topics: Animals; Bacteria; Calcium; Cecum; Diltiazem; Intestinal Mucosa; Lymph Nodes; Male; Mesentery; Phosp | 1995 |
Phospholipase A(2)--derived neutral lipids from posthemorrhagic shock mesenteric lymph prime the neutrophil oxidative burst.
Topics: Animals; Enzyme Inhibitors; Leukotriene B4; Lymph; Male; Neutrophils; Phospholipases A; Quinacrine; | 2001 |
Post-hemorrhagic shock mesenteric lymph lipids prime neutrophils for enhanced cytotoxicity via phospholipase A2.
Topics: Animals; Digestive System; Enzyme Inhibitors; Lipid Metabolism; Lymphatic System; Male; Mesentery; N | 2001 |