quinacrine has been researched along with Hemolysis in 10 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dantrolene is an effective antagonist of anesthesia-induced malignant hyperthermia due to a poorly understood action on skeletal muscle." | 5.27 | Dantrolene and mepacrine antagonize the hemolysis of human red blood cells by halothane and bee venom phospholipase A2. ( Fletcher, JE; Kistler, P; Michaux, K; Rosenberg, H, 1987) |
| "Mepacrine at 50 microM completely protected vitamin E-deficient rat erythrocytes from peroxidative hemolysis induced by dialuric acid or reduced glutathione under the standard experimental conditions." | 3.66 | Inhibition of oxidative hemolysis and lipid peroxidation by mepacrine. ( Hibasami, H; Ikeda, T; Nagai, J; Tanaka, M, 1981) |
| "Dantrolene is an effective antagonist of anesthesia-induced malignant hyperthermia due to a poorly understood action on skeletal muscle." | 1.27 | Dantrolene and mepacrine antagonize the hemolysis of human red blood cells by halothane and bee venom phospholipase A2. ( Fletcher, JE; Kistler, P; Michaux, K; Rosenberg, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Officioso, A | 1 |
| Alzoubi, K | 1 |
| Manna, C | 1 |
| Lang, F | 1 |
| Wagner, SJ | 1 |
| Skripchenko, A | 1 |
| Thompson-Montgomery, D | 1 |
| Nagai, J | 1 |
| Tanaka, M | 1 |
| Hibasami, H | 1 |
| Ikeda, T | 1 |
| Sugimoto, N | 1 |
| Haque, A | 1 |
| Horiguchi, Y | 1 |
| Matsuda, M | 1 |
| Igarashi, T | 1 |
| Aritake, S | 1 |
| Yasumoto, T | 1 |
| Evans, J | 1 |
| Wang, YD | 1 |
| Shaw, KP | 1 |
| Vernon, LP | 1 |
| Fletcher, JE | 1 |
| Kistler, P | 1 |
| Rosenberg, H | 1 |
| Michaux, K | 1 |
| Levy, MR | 1 |
| Chou, SC | 1 |
| Miller, A | 2 |
| Smith, HC | 2 |
10 other studies available for quinacrine and Hemolysis
| Article | Year |
|---|---|
Clofazimine Induced Suicidal Death of Human Erythrocytes.
Topics: Adenosine Triphosphate; Annexin A5; Calcium; Cell Death; Cell Size; Clofazimine; Cytosol; Erythrocyt | 2015 |
Quinacrine enhances vesicular stomatitis virus inactivation and diminishes hemolysis of dimethylmethylene blue-phototreated red cells.
Topics: Blood Preservation; Drug Interactions; Erythrocyte Membrane; Erythrocytes; Hemolysis; Light; Methyle | 2002 |
Inhibition of oxidative hemolysis and lipid peroxidation by mepacrine.
Topics: Animals; Barbiturates; Erythrocytes; Glutathione; Hemolysis; Lipid Peroxides; Male; Malondialdehyde; | 1981 |
Coronary vasoconstriction is the most probable cause of death of rats intoxicated with botulinolysin, a hemolysin produced by Clostridium botulinum.
Topics: Animals; Aspirin; Blood Pressure; Botulinum Toxins; Botulism; Clostridium botulinum; Electrocardiogr | 1995 |
Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Cellular responses to Pyrularia thionin are mediated by Ca2+ influx and phospholipase A2 activation and are inhibited by thionin tyrosine iodination.
Topics: Animals; Antimicrobial Cationic Peptides; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; C | 1989 |
Dantrolene and mepacrine antagonize the hemolysis of human red blood cells by halothane and bee venom phospholipase A2.
Topics: Bee Venoms; Dantrolene; Dose-Response Relationship, Drug; Halothane; Hemolysis; Humans; Hydrolysis; | 1987 |
Activity and some properties of an acid proteinase from normal and Plasmodium berghei-infected red cells.
Topics: Acid Phosphatase; Animals; Cell-Free System; Chloroquine; Dithiothreitol; Edetic Acid; Erythrocytes; | 1973 |
The influence of glucose and exogenous glutathione on the red cell membrane effect of the antimalarial drugs 1,4-naphthoquinone and beta-naphthol.
Topics: Cell Membrane; Erythrocytes; Glucose; Glutathione; Hemolysis; Humans; In Vitro Techniques; Methemogl | 1971 |
The intracellular and membrane effects of oxidant agents on normal red cells.
Topics: Cell Membrane; Erythrocytes; Glutathione; Heinz Bodies; Hemoglobinometry; Hemolysis; Humans; Hydroqu | 1970 |