quinacrine has been researched along with Edema in 10 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " africana was examined for topical antiinflammatory activity and proved to be active against arachidonic acid (AA) acute edema, 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced chronic inflammation, and oxazolone delayed-type hypersensitivity in mice." | 3.69 | Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark. ( Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL, 1997) |
| "Oedema was maximal within 1 h after BJV injection, was partially reduced at 6 h and disappeared completely within 24 h." | 1.28 | Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom. ( Calixto, JB; Trebien, HA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cuéllar, MJ | 1 |
| Giner, RM | 1 |
| Recio, MC | 1 |
| Just, MJ | 1 |
| Máñez, S | 1 |
| Cerdá, M | 1 |
| Hostettmann, K | 1 |
| Ríos, JL | 1 |
| REESE, FM | 1 |
| CHAMBERLAIN, WP | 1 |
| BOLES, DJ | 1 |
| Hanna, PC | 1 |
| Kruskal, BA | 1 |
| Ezekowitz, RA | 1 |
| Bloom, BR | 1 |
| Collier, RJ | 1 |
| Higgs, GA | 1 |
| Harvey, EA | 1 |
| Ferreira, SH | 1 |
| Vane, JR | 1 |
| Moreno, JJ | 1 |
| Ferrer, X | 1 |
| Ortega, E | 1 |
| Carganico, G | 1 |
| Trebien, HA | 1 |
| Calixto, JB | 1 |
| Yoshioka, A | 1 |
| Miyachi, Y | 1 |
| Imamura, S | 1 |
| Freeman, RG | 1 |
| Knox, JM | 1 |
| Owens, DW | 1 |
10 other studies available for quinacrine and Edema
| Article | Year |
|---|---|
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibi | 1997 |
Edema of the corneal epithelium caused by atabrine; observation on three patients.
Topics: Edema; Epithelium, Corneal; Quinacrine | 1946 |
CORNEAL edema; unusual toxic reaction to atabrine.
Topics: Corneal Edema; Edema; Postoperative Complications; Quinacrine | 1946 |
Edema of cornea precipitated by quinacrine (atabrine).
Topics: Cornea; Corneal Diseases; Disease; Edema; Quinacrine | 1946 |
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Topics: Animals; Antigens, Bacterial; Antioxidants; Ascorbic Acid; Bacillus anthracis; Bacterial Toxins; Cel | 1994 |
The effects of antiinflammatory drugs on the production of prostaglandins in vivo.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Movement; Colchicine; | 1976 |
PLA2-induced oedema in rat skin and histamine release in rat mast cells. Evidence for involvement of lysophospholipids in the mechanism of action.
Topics: Animals; Aristolochic Acids; Cytoplasmic Granules; Dexamethasone; Edema; Histamine Release; In Vitro | 1992 |
Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom.
Topics: Animals; Captopril; Crotalid Venoms; Dexamethasone; Edema; Hot Temperature; Indomethacin; Male; Maso | 1989 |
The mechanism of the inhibitory effects of antimalarials on UV-induced skin inflammation in mice.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chloroquine; Ear, External; Edema; Female; Inflammatio | 1988 |
Cutaneous lesions of lupus erythematosus induced by monochromatic light.
Topics: Acanthosis Nigricans; Edema; Erythema; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Sy | 1969 |