quinacrine has been researched along with Edema, Pulmonary in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A good model of the adult respiratory distress syndrome (ARDS) is intravenously injected phorbol myristate acetate (PMA), which causes pulmonary sequestration of neutrophils and a neutrophil-dependent acute edematous lung injury in rabbits." | 1.27 | Mepacrine but not methylprednisolone decreases acute edematous lung injury after injection of phorbol myristate acetate in rabbits. ( Canham, EM; Harada, RN; McMurtry, IF; Repine, JE; Shoemaker, SA; Tate, RM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Canham, EM | 1 |
| Shoemaker, SA | 1 |
| Tate, RM | 1 |
| Harada, RN | 1 |
| McMurtry, IF | 1 |
| Repine, JE | 2 |
| Sugimoto, N | 1 |
| Haque, A | 1 |
| Horiguchi, Y | 1 |
| Matsuda, M | 1 |
| Lee, YM | 1 |
| Hybertson, BM | 1 |
| Terada, LS | 1 |
| Repine, AJ | 1 |
| Cho, HG | 1 |
| Chao, TJ | 1 |
| Chou, CL | 1 |
| Hsu, K | 1 |
| Wang, D | 1 |
4 other studies available for quinacrine and Edema, Pulmonary
| Article | Year |
|---|---|
Mepacrine but not methylprednisolone decreases acute edematous lung injury after injection of phorbol myristate acetate in rabbits.
Topics: Animals; Lung; Methylprednisolone; Neutrophils; Phorbols; Premedication; Pulmonary Edema; Quinacrine | 1983 |
Coronary vasoconstriction is the most probable cause of death of rats intoxicated with botulinolysin, a hemolysin produced by Clostridium botulinum.
Topics: Animals; Aspirin; Blood Pressure; Botulinum Toxins; Botulism; Clostridium botulinum; Electrocardiogr | 1995 |
Mepacrine decreases lung leak in rats given interleukin-1 intratracheally.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Adhesion; Cells, Cultured; Chemokine CXCL1; Chemokines, | 1997 |
The protective effect of mepacrine on acute lung edema induced by phorbol myristate acetate in rats.
Topics: Animals; Luminescent Measurements; Lung; Pulmonary Edema; Quinacrine; Rats; Rats, Inbred Strains; Te | 1990 |