quinacrine has been researched along with Drug-Related Side Effects and Adverse Reactions in 11 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phospholipidosis (PLD) is a lysosomal storage disorder induced by compounds, notably cationic amphiphilic drugs, which although reversible interferes with cellular phospholipids." | 1.38 | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. ( Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, H | 1 |
| Atzpodien, EA | 1 |
| Csato, M | 1 |
| Doessegger, L | 1 |
| Lenz, B | 1 |
| Schmitt, G | 1 |
| Singer, T | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| BURNHAM, RC | 1 |
| RAUSCHKE, J | 1 |
| BURGER, E | 1 |
| HARPEL, HS | 1 |
| MANN, DE | 1 |
| Mori, T | 1 |
| Ito, S | 1 |
| Namiki, M | 1 |
| Suzuki, T | 1 |
| Kobayashi, S | 1 |
| Matsubayashi, K | 1 |
| Sawaguchi, T | 1 |
| Havey, RJ | 1 |
| Kumar, S | 1 |
| Mudur, G | 1 |
| Patel, T | 1 |
| Meier-Ruge, W | 1 |
2 reviews available for quinacrine and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Over-the-counter and iatrogenically induced psychoses: a review of the literature.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Appetite Depressants; Aspirin; Cimetidine; Disulfir | 1984 |
Drug induced retinopathy.
Topics: Adsorption; Animals; Antineoplastic Agents; Chloroquine; Drug-Related Side Effects and Adverse React | 1969 |
9 other studies available for quinacrine and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Acute atabrine intoxication.
Topics: Drug-Related Side Effects and Adverse Reactions; Psychoses, Substance-Induced; Quinacrine | 1946 |
[Fatal quinine poisoning with simultaneous atebrine effects; report on results of quantitative analysis].
Topics: Cardiovascular Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Quinacrine; Quinine | 1957 |
ANTAGONISM OF DEXTRO-PROPOXYPHENE POISONING IN ALBINO MICE WITH NALORPHINE HC1, LEVALLORPHAN TARTRATE, AND METHYLENE BLU.
Topics: Analgesics; Animals; Antidotes; Dextropropoxyphene; Drug-Related Side Effects and Adverse Reactions; | 1965 |
Involvement of free radicals followed by the activation of phospholipase A2 in the mechanism that underlies the combined effects of methamphetamine and morphine on subacute toxicity or lethality in mice: comparison of the therapeutic potential of fulleren
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug | 2007 |
Quinacrine sterilisation trials in India delayed.
Topics: Contraception; Drug-Related Side Effects and Adverse Reactions; Female; Human Experimentation; Human | 1995 |
India to ban female sterilisation with malaria drug.
Topics: Chile; Contraception; Costa Rica; Developing Countries; Drug-Related Side Effects and Adverse Reacti | 1998 |
Row over sterilisation divides India.
Topics: Developing Countries; Drug-Related Side Effects and Adverse Reactions; Female; Human Experimentation | 1997 |