quinacrine has been researched along with Diabetes Mellitus, Adult-Onset in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiotensin II (Ang II) is able to induce free radical generation in neutrophils, which is more elevated in neutrophils of patients with hypercholesterolemia (HC)." | 7.73 | The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome. ( Balogh, Z; Fóris, G; Fülöp, P; Kassai, A; Kosztáczky, B; Paragh, G; Seres, I; Varga, Z, 2006) |
| "Angiotensin II (Ang II) is able to induce free radical generation in neutrophils, which is more elevated in neutrophils of patients with hypercholesterolemia (HC)." | 3.73 | The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome. ( Balogh, Z; Fóris, G; Fülöp, P; Kassai, A; Kosztáczky, B; Paragh, G; Seres, I; Varga, Z, 2006) |
| " Enhanced oxidative stress in hypertension and diabetes is linked to decreased nitric oxide (NO) bioavailability because of its interaction with vascular superoxide (O(2)(*-)), derived predominantly from NAD(P)H-dependent oxidases." | 1.33 | Increased superoxide production in hypertensive patients with diabetes mellitus: role of nitric oxide synthase. ( Devine, A; Dixon, LJ; Henry, W; Hughes, SM; Johnston, GD; Leahey, W; Madden, A; McVeigh, GE; Rooney, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 3 |
| Zhou, J | 3 |
| Hu, Z | 3 |
| Han, L | 3 |
| Zhao, W | 3 |
| Wu, T | 3 |
| Li, C | 3 |
| Liu, J | 3 |
| Kang, J | 3 |
| Chen, X | 3 |
| Dixon, LJ | 1 |
| Hughes, SM | 1 |
| Rooney, K | 1 |
| Madden, A | 1 |
| Devine, A | 1 |
| Leahey, W | 1 |
| Henry, W | 1 |
| Johnston, GD | 1 |
| McVeigh, GE | 1 |
| Seres, I | 1 |
| Fóris, G | 1 |
| Varga, Z | 1 |
| Kosztáczky, B | 1 |
| Kassai, A | 1 |
| Balogh, Z | 1 |
| Fülöp, P | 1 |
| Paragh, G | 1 |
| Powrie, JK | 1 |
| Watts, GF | 1 |
| Smith, GD | 1 |
| Sönksen, PH | 1 |
| Jones, RH | 1 |
1 trial available for quinacrine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Short-term effects of mepacrine on serum lipids, lipoproteins, and apolipoproteins in patients with non-insulin-dependent diabetes mellitus.
Topics: Adult; Apolipoproteins; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Lipids; Lipo | 1994 |
3 other studies available for quinacrine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; | 2023 |
Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; | 2023 |
Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; | 2023 |
Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; | 2023 |
Increased superoxide production in hypertensive patients with diabetes mellitus: role of nitric oxide synthase.
Topics: Adult; Aged; Biomarkers; Biphenyl Compounds; Blood Platelets; Diabetes Mellitus, Type 2; Enzyme Inhi | 2005 |
The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome.
Topics: Adult; Angiotensin I; Angiotensin II; Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Type | 2006 |