quinacrine has been researched along with Dermatitis, Contact in 6 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine (QC) is an anti-inflammatory drug that has been used for the treatment of malaria and rheumatoid diseases." | 5.34 | Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation. ( Fairchild, RL; Gasparian, AV; Gorbachev, AV; Gudkov, AV; Gurova, KV, 2007) |
| " africana was examined for topical antiinflammatory activity and proved to be active against arachidonic acid (AA) acute edema, 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced chronic inflammation, and oxazolone delayed-type hypersensitivity in mice." | 3.69 | Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark. ( Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL, 1997) |
| "Quinacrine (QC) is an anti-inflammatory drug that has been used for the treatment of malaria and rheumatoid diseases." | 1.34 | Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation. ( Fairchild, RL; Gasparian, AV; Gorbachev, AV; Gudkov, AV; Gurova, KV, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cuéllar, MJ | 1 |
| Giner, RM | 1 |
| Recio, MC | 1 |
| Just, MJ | 1 |
| Máñez, S | 1 |
| Cerdá, M | 1 |
| Hostettmann, K | 1 |
| Ríos, JL | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| SINGH, I | 1 |
| HERRMANN, WP | 1 |
| SCHULZ, KH | 1 |
| BRODTHAGEN, H | 1 |
| CHRISTIANSEN, JV | 1 |
| Gorbachev, AV | 1 |
| Gasparian, AV | 1 |
| Gurova, KV | 1 |
| Gudkov, AV | 1 |
| Fairchild, RL | 1 |
6 other studies available for quinacrine and Dermatitis, Contact
| Article | Year |
|---|---|
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibi | 1997 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Mepacrine dermatitis.
Topics: Acridines; Coloring Agents; Dermatitis; Dermatitis, Contact; Humans; Quinacrine | 1948 |
[ALLERGIC CONTACT ECZEMA CAUSED BY RESOCHIN].
Topics: Chloroquine; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Contact; Quinacrine; Skin Tests; | 1965 |
Chronic polymorphic light eruptions treated with mepacrine.
Topics: Dermatitis, Contact; Humans; Light; Quinacrine; Skin Diseases | 1955 |
Quinacrine inhibits the epidermal dendritic cell migration initiating T cell-mediated skin inflammation.
Topics: Animals; Anti-Inflammatory Agents; CD8-Positive T-Lymphocytes; Chemokine CCL21; Chemokines, CC; Chem | 2007 |