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quinacrine and Degenerative Diseases, Central Nervous System

quinacrine has been researched along with Degenerative Diseases, Central Nervous System in 2 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spilman, P1
Lessard, P1
Sattavat, M1
Bush, C1
Tousseyn, T1
Huang, EJ1
Giles, K1
Golde, T1
Das, P1
Fauq, A1
Prusiner, SB1
Dearmond, SJ1
Ong, WY1
Lu, XR1
Horrocks, LA1
Farooqui, AA1
Garey, LJ1

Other Studies

2 other studies available for quinacrine and Degenerative Diseases, Central Nervous System

ArticleYear
A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-29, Volume: 105, Issue:30

    Topics: Administration, Oral; Alanine; Amyloid Precursor Protein Secretases; Animals; Azepines; Brain; Dendr

2008
Induction of astrocytic cytoplasmic phospholipase A2 and neuronal death after intracerebroventricular carrageenan injection, and neuroprotective effects of quinacrine.
    Experimental neurology, 2003, Volume: 183, Issue:2

    Topics: Animals; Astrocytes; Carrageenan; Cell Death; Disease Progression; Enzyme Induction; Gliosis; Inject

2003