quinacrine has been researched along with Deep Vein Thrombosis in 1 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using the stasis model of venous thrombosis and resolution in mice, we found that genetic deficiency of p53 or pharmacologic inhibition by pifithrin impairs thrombus resolution and is associated with increased fibrosis and altered expression of matrix metalloproteinase-2." | 1.46 | Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice. ( Antalis, TM; Hoofnagle, MH; Mukhopadhyay, S; Nguyen, KP; Sarkar, R, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mukhopadhyay, S | 1 |
| Antalis, TM | 1 |
| Nguyen, KP | 1 |
| Hoofnagle, MH | 1 |
| Sarkar, R | 1 |
1 other study available for quinacrine and Deep Vein Thrombosis
| Article | Year |
|---|---|
Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.
Topics: Animals; Disease Models, Animal; Fibrosis; Gene Expression Regulation, Enzymologic; Macrophages; Mat | 2017 |