quinacrine has been researched along with Colitis, Ulcerative in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine is an anti-malarial drug with versatile use in the treatment of diseases involving inflammatory response such as rheumatoid arthritis and lupus erythematosus." | 1.43 | Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties. ( Chaparala, A; Chumanevich, A; Chumanevich, AA; Hofseth, LJ; Nagarkatti, M; Nagarkatti, P; Witalison, EE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chumanevich, AA | 1 |
| Witalison, EE | 1 |
| Chaparala, A | 1 |
| Chumanevich, A | 1 |
| Nagarkatti, P | 1 |
| Nagarkatti, M | 1 |
| Hofseth, LJ | 1 |
| Wardle, TD | 1 |
| Turnberg, LA | 1 |
2 other studies available for quinacrine and Colitis, Ulcerative
| Article | Year |
|---|---|
Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties.
Topics: Animals; Antimalarials; Cell Line; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dextran Sulfate; Di | 2016 |
Potential role for interleukin-1 in the pathophysiology of ulcerative colitis.
Topics: Adult; Animals; Colitis, Ulcerative; Colon; Culture Media; Culture Techniques; Dinoprostone; Dose-Re | 1994 |