quinacrine has been researched along with Chronic Illness in 23 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two Giardia isolates were axenised in vitro after recovery by duodenal aspiration from a man with hypo-gamma globulinaemia and chronic giardiasis, before and after three unsuccessful courses of metronidazole." | 3.69 | Phenotypic and genotypic variation in Giardia lamblia isolates during chronic infection. ( Alstead, EM; Butcher, PD; Carnaby, S; Cevallos, AM; Farthing, MJ; Swarbrick, ET, 1994) |
| ") with chronic symptomatic Giardiasis despite seven separate courses of either quinacrine or metronidazole who was cured by combined quinacrine and metronidazole." | 3.66 | Chronic giardiasis: studies on drug sensitivity, toxin production, and host immune response. ( Gillin, FD; Nash, TE; Smith, PD; Spira, WM, 1982) |
| "We conclude that giardiasis is frequently a chronic disease in our population with symptoms lasting years." | 1.27 | Giardiasis as a chronic disease. ( Chester, AC; MacMurray, FG; Mann, O; Restifo, MD, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (78.26) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haseman, JK | 1 |
| Growe, RG | 1 |
| Zeiger, E | 1 |
| McConnell, EE | 1 |
| Luster, MI | 1 |
| Lippes, J | 1 |
| DOBROTVORSKAIA, NV | 1 |
| BAKER, BM | 1 |
| PLATT, D | 1 |
| CHOWDHURY, MZ | 1 |
| Genel, F | 1 |
| Erermis, S | 1 |
| Aksu, G | 1 |
| Ozturk, C | 1 |
| Kutukculer, N | 1 |
| RADKE, RA | 1 |
| FORESTIER, J | 1 |
| CERTONCINY, A | 1 |
| CHRISTIANSEN, JV | 1 |
| NIELSEN, JP | 1 |
| Bond, JH | 1 |
| Smith, PD | 1 |
| Gillin, FD | 1 |
| Spira, WM | 1 |
| Nash, TE | 1 |
| Butcher, PD | 1 |
| Cevallos, AM | 1 |
| Carnaby, S | 1 |
| Alstead, EM | 1 |
| Swarbrick, ET | 1 |
| Farthing, MJ | 1 |
| Kapur, RP | 1 |
| Sheehy, TW | 1 |
| Holley, HP | 1 |
| Rowedder, A | 1 |
| Meier, R | 1 |
| Wegmann, W | 1 |
| Gyr, K | 1 |
| Chester, AC | 1 |
| MacMurray, FG | 1 |
| Restifo, MD | 1 |
| Mann, O | 1 |
| al Karawi, M | 1 |
| Salam, I | 1 |
| Mohamed, AE | 1 |
| Taylor, GD | 1 |
| Wenman, WM | 1 |
| Tyrrell, DL | 1 |
| Hohenauer, I | 1 |
| Schmoigl, S | 1 |
| Trier, JS | 1 |
| Moxey, PC | 1 |
| Schimmel, EM | 1 |
| Robles, E | 1 |
| Myint, UH | 1 |
| Win, UK | 1 |
| Criswell, BS | 1 |
| Butler, WT | 1 |
| Rossen, RD | 1 |
| Knight, V | 1 |
| Cairns, JE | 1 |
| Winkelmann, RK | 1 |
1 review available for quinacrine and Chronic Illness
| Article | Year |
|---|---|
Neuropathology of paediatric chronic intestinal pseudo-obstruction and related animal models.
Topics: Animals; Anthraquinones; Antimalarials; Autonomic Nervous System Diseases; Cathartics; Chronic Disea | 2001 |
22 other studies available for quinacrine and Chronic Illness
| Article | Year |
|---|---|
A critical examination of the mode of action of quinacrine in the reproductive tract in a 2-year rat cancer bioassay and its implications for human clinical use.
Topics: Animals; Cell Transformation, Neoplastic; Chemistry, Pharmaceutical; Chronic Disease; Contraceptive | 2015 |
[Clinical aspects and relapse of leishmaniasis following acrichine therapy].
Topics: Chronic Disease; Leishmaniasis; Quinacrine; Recurrence | 1948 |
Vivax relapse rates following continued atabrine suppressive medication; observations on malaria in an infantry regiment.
Topics: Chronic Disease; Humans; Malaria; Malaria, Vivax; Quinacrine; Recurrence | 1947 |
Mepacrine and the relapse-rate of malaria.
Topics: Chronic Disease; Malaria; Quinacrine; Recurrence | 1946 |
Quinacrine-induced psychiatric disturbances in a child with common variable immunodeficiency and chronic giardiasis.
Topics: Anti-Anxiety Agents; Antiprotozoal Agents; Antipsychotic Agents; Benzodiazepines; Child; Chronic Dis | 2002 |
Diagnosis and treatment of chronic amebiasis.
Topics: Amebiasis; Arsanilic Acid; Chronic Disease; Dysentery, Amebic; Quinacrine | 1952 |
[Serological research in chronic inflammatory rheumatism; study of antistreptolysin O].
Topics: Antistreptolysin; Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Humans; Quinacrine; Research; | 1954 |
Treatment of lupus erythematosus with mepacrine; results and relapses during a long observation.
Topics: Chronic Disease; Lupus Erythematosus, Systemic; Quinacrine; Recurrence | 1956 |
Office-based management of diarrhea.
Topics: Acute Disease; Aged; Antacids; Anti-Bacterial Agents; Cathartics; Chronic Disease; Diarrhea; Diet; D | 1982 |
Chronic giardiasis: studies on drug sensitivity, toxin production, and host immune response.
Topics: Adult; Antibodies; Chronic Disease; Drug Resistance; Enterotoxins; Giardia; Giardiasis; Humans; Male | 1982 |
Phenotypic and genotypic variation in Giardia lamblia isolates during chronic infection.
Topics: Adult; Animals; Chronic Disease; DNA Fingerprinting; Genotype; Giardia lamblia; Giardiasis; Humans; | 1994 |
Giardia-induced malabsorption in pancreatitis.
Topics: Adult; Chronic Disease; Feces; Giardia; Giardiasis; Humans; Malabsorption Syndromes; Male; Middle Ag | 1975 |
[Combined oral and endoscopic mepacrine therapy in therapy-resistant symptomatic giardiasis].
Topics: Administration, Oral; Adult; Antiprotozoal Agents; Chronic Disease; Duodenoscopy; Giardiasis; Humans | 1991 |
Giardiasis as a chronic disease.
Topics: Adult; Aged; Chronic Disease; District of Columbia; Feces; Female; Giardia; Giardiasis; Humans; Male | 1985 |
Combined oral and endoscopic mepacrine therapy in a case of persistent chronic symptomatic giardiasis.
Topics: Administration, Oral; Adult; Chronic Disease; Duodenoscopy; Giardiasis; Humans; Intestinal Diseases, | 1988 |
Combined metronidazole and quinacrine hydrochloride therapy for chronic giardiasis.
Topics: Agammaglobulinemia; Chronic Disease; Drug Therapy, Combination; Giardiasis; Humans; Male; Metronidaz | 1987 |
[Experience with a combination of ethosuximide and mepacrine (Acrisuxin) in the treatment of chronic epileptic seizures in children].
Topics: Child; Child, Preschool; Chronic Disease; Drug Combinations; Epilepsy; Epilepsy, Absence; Epilepsy, | 1972 |
Chronic intestinal coccidiosis in man: intestinal morphology and response to treatment.
Topics: Antiprotozoal Agents; Biopsy; Chloroquine; Chronic Disease; Coccidiosis; Diagnosis, Differential; Di | 1974 |
The routine treatment of malaria.
Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease | 1971 |
Murine malaria: the role of humoral factors and macrophages in destruction of parasitized erythrocytes.
Topics: Animals; Chronic Disease; Endotoxins; Erythrocytes; Immunity; Immunity, Cellular; Iodine Isotopes; M | 1971 |
Cutaneous leishmaniasis (Oriental sore). A case with corneal involvement.
Topics: Adolescent; Chronic Disease; Female; Humans; Keratitis; Leishmaniasis; Quinacrine; Uveitis | 1968 |
Chronic discoid lupus erythematosus in children.
Topics: Adolescent; Adult; Child; Chronic Disease; Cortisone; Fluocinolone Acetonide; Flurandrenolone; Human | 1968 |