Page last updated: 2024-10-16

quinacrine and Chromosome Inversion

quinacrine has been researched along with Chromosome Inversion in 6 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Chromosome Inversion: An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome.

Research Excerpts

ExcerptRelevanceReference
"The total incidence of major chromosome aberrations including numerical changes of the sex chromosomes, and structural changes of autosomes, was 0."1.26Chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique. ( Gedeon, MM; Griffith, P; Lin, CC; Newton, DR; Sewell, LM; Smink, WK; Wilkie, L, 1976)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, CC1
Gedeon, MM1
Griffith, P1
Smink, WK1
Newton, DR1
Wilkie, L1
Sewell, LM1
Soudek, D2
Sroka, H1
Miller, DA1
O'Shaughnessy, S1
Laraya, P1
McCreary, BD1
Breg, WR1
Soukup, SW1
Yarema, W1
Robinow, M1

Other Studies

6 other studies available for quinacrine and Chromosome Inversion

ArticleYear
Chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique.
    Human genetics, 1976, Mar-12, Volume: 31, Issue:3

    Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes, Human, 1-3; Chromos

1976
Inversion of 'flourescent' segment in chromosome 3: a polymorphic trait.
    Human genetics, 1978, Oct-31, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Child; Chromosome Banding; Chromosome Inversion; Chromosomes, Human, 1-3; Female;

1978
Evolution of primate chromosomes.
    Science (New York, N.Y.), 1977, Dec-16, Volume: 198, Issue:4322

    Topics: Animals; Biological Evolution; Chromosome Aberrations; Chromosome Inversion; Chromosome Mapping; Chr

1977
Pericentric inversion of "fluorescent" segment in chromosome no. 3.
    Humangenetik, 1974, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Huma

1974
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
    Birth defects original article series, 1974, Volume: 10, Issue:8

    Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human,

1974
A pericentric inversion of a chromosome 4 with a t(4q+10p-) and a familial t(DqDq) in a mentally retarded girl.
    Humangenetik, 1974, Volume: 25, Issue:1

    Topics: ABO Blood-Group System; Acridines; Blood Group Antigens; Child; Chromosome Aberrations; Chromosome I

1974