quinacrine has been researched along with Chromosome Deletion in 7 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "6 microg/ml QDH, exhibited chromosome aberrations including dicentrics, ring configurations, translocations, inversions, and marker chromosomes." | 1.31 | Quinacrine dihydrochloride, the non-surgical female sterilant induces dicentrics, rings, and marker chromosomes in human peripheral blood lymphocytes treated in vitro: a preliminary report. ( Chauhan, PS; Krishnaja, AP, 2000) |
| "These chromosome abnormalities were compared to previous cytogenic analyses on the transplantable Shay chloroleukemia, in which new fluorescent banding techniques were not utilized." | 1.26 | Chromosome studies of the transplantable Shay chloroleukemia in rats. ( Alt, B, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Leval, L | 1 |
| Defraigne, JO | 1 |
| Hermans, G | 1 |
| Dôme, F | 1 |
| Boniver, J | 1 |
| Herens, C | 1 |
| Fowler, G | 1 |
| Kaiser-McCaw, B | 1 |
| Hecht, F | 1 |
| Krishnaja, AP | 1 |
| Chauhan, PS | 1 |
| Miller, DA | 1 |
| Tantravahi, R | 1 |
| Dev, VG | 1 |
| Miller, OJ | 1 |
| Alt, B | 1 |
| Niebuhr, E | 1 |
| Gasc, AM | 1 |
| Sicard, AM | 1 |
7 other studies available for quinacrine and Chromosome Deletion
| Article | Year |
|---|---|
Malignant solitary fibrous tumor of the pleura: report of a case with cytogenetic analysis.
Topics: Aneuploidy; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, Pair 8; Fatal Outcome; Huma | 2003 |
The use of sequential silver and quinacrine staining to determine the parental origin and breakpoints of a ring-22 human chromosome.
Topics: Abnormalities, Multiple; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome D | 1980 |
Quinacrine dihydrochloride, the non-surgical female sterilant induces dicentrics, rings, and marker chromosomes in human peripheral blood lymphocytes treated in vitro: a preliminary report.
Topics: Adult; Chromosome Aberrations; Chromosome Deletion; Cytogenetic Analysis; Female; Humans; Lymphocyte | 2000 |
Frequency of satellite association of human chromosomes is correlated with amount of Ag-staining of the nucleolus organizer region.
Topics: Cell Nucleolus; Chromosome Deletion; Chromosomes; Cytological Techniques; DNA; DNA, Satellite; Femal | 1977 |
Chromosome studies of the transplantable Shay chloroleukemia in rats.
Topics: Animals; Chromosome Aberrations; Chromosome Deletion; Fluorescent Dyes; Leukemia, Experimental; Leuk | 1977 |
Cytologic observations in 35 individuals with a 5p- karyotype.
Topics: Acridines; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, 4-5; Cri-du-Chat Syndrom | 1978 |
Frame-shift mutants induced by quinacrine are recognized by the mismatch repair system in Streptococcus pneumoniae.
Topics: Base Sequence; Chromosome Deletion; DNA Repair; Drug Resistance, Microbial; Genes, Bacterial; Methot | 1986 |