quinacrine has been researched along with Chromosomal Triplication in 39 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These chromosome abnormalities were compared to previous cytogenic analyses on the transplantable Shay chloroleukemia, in which new fluorescent banding techniques were not utilized." | 1.26 | Chromosome studies of the transplantable Shay chloroleukemia in rats. ( Alt, B, 1977) |
| "2 had total and partial No." | 1.26 | Reproducible chromosome changes of polycyclic hydrocarbon-induced rat leukemia: incidence and chromosome banding pattern. ( Fukuhara, S; Maeda, S; Sugiyama, T; Ueda, N; Uenaka, H, 1978) |
| "Chromosomal abnormalities were detected in 59% of the specimens." | 1.25 | Recent advances in the cytogenetic study of human spontaneous abortions. ( Carr, DH; McConnell, HD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moser, GC | 1 |
| Müller, H | 2 |
| Robbins, E | 1 |
| Penchaszadeh, VB | 1 |
| Coco, R | 1 |
| Korenberg, JR | 1 |
| Therman, E | 1 |
| Denniston, C | 1 |
| Habedank, M | 1 |
| Faust, J | 1 |
| Alt, B | 1 |
| Hunter, AG | 1 |
| Ray, M | 1 |
| Langston, C | 1 |
| Sugiyama, T | 1 |
| Uenaka, H | 1 |
| Ueda, N | 1 |
| Fukuhara, S | 1 |
| Maeda, S | 1 |
| Pérez-Castillo, A | 1 |
| Abrisqueta, JA | 1 |
| Robson, EB | 1 |
| Hopkinson, DA | 1 |
| Buckton, KE | 3 |
| Robinson, J | 1 |
| Polani, PE | 1 |
| McConnell, HD | 1 |
| Carr, DH | 1 |
| O'Riordan, ML | 1 |
| Robinson, JA | 1 |
| Evans, HJ | 1 |
| Bühler, EM | 1 |
| Stalder, GR | 1 |
| Werder, E | 1 |
| Pawlowitzki, IH | 1 |
| Caspersson, T | 2 |
| Lindsten, J | 2 |
| Zech, L | 2 |
| Price, WH | 1 |
| Pearson, P | 1 |
| White, BJ | 1 |
| Tjio, JH | 1 |
| Van de Water, LC | 1 |
| Crandall, C | 1 |
| Uchida, IA | 1 |
| Lin, CC | 1 |
| De la Chapelle, A | 3 |
| Schröder, J | 3 |
| Vuopio, P | 1 |
| Lomakka, G | 1 |
| Moller, A | 1 |
| Miller, OJ | 4 |
| Miller, DA | 4 |
| Warburton, D | 1 |
| Koivisto, M | 1 |
| Shaw, MW | 1 |
| Holbek, S | 1 |
| Friedrich, U | 1 |
| Lauritsen, JG | 1 |
| Therkelsen, J | 1 |
| Fujita, H | 1 |
| Abe, T | 1 |
| Yamamoto, K | 1 |
| Furuyama, J | 1 |
| Breg, WR | 5 |
| Allderdice, PW | 3 |
| Benirschike, K | 1 |
| Bogart, MH | 1 |
| McClure, HM | 1 |
| Nelson-Rees, WA | 1 |
| Cohen, MM | 1 |
| Finch, AB | 1 |
| Lubs, HA | 1 |
| Falk, RE | 1 |
| Carrel, RE | 1 |
| Valente, M | 1 |
| Crandall, BF | 1 |
| Sparkes, RS | 1 |
| Van den Berghe, H | 1 |
| Van Eygen, M | 1 |
| Fryns, JP | 1 |
| Tanghe, W | 1 |
| Verresen, H | 1 |
| Franceschini, HP | 1 |
| Fabris, C | 1 |
| Ponzone, A | 1 |
| Rosenthal, IM | 1 |
| Krmpotic, E | 1 |
| Bocian, M | 1 |
| Szego, K | 1 |
| Traut, H | 1 |
| Scheid, W | 1 |
| Francke, U | 1 |
| Gustavson, KH | 1 |
| Hitrec, V | 1 |
| Santesson, B | 1 |
| Short, EM | 1 |
| Solitare, GB | 1 |
| Kaski, U | 1 |
| Forsius, H | 1 |
| Gendel, E | 1 |
| Zelson, C | 1 |
3 reviews available for quinacrine and Chromosomal Triplication
| Article | Year |
|---|---|
The use of new staining techniques for human chromosome identification.
Topics: Binding Sites; Cell Nucleus; Chromosomes; DNA; Evaluation Studies as Topic; Female; Fluoresceins; Hu | 1972 |
The use of fluorescence techniques for the recognition of mammalian chromosomes and chromosome regions.
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Chromosomes, Human, 16-18; Chrom | 1972 |
Application of new staining techniques to the study of human chromosomes.
Topics: Base Sequence; Burkitt Lymphoma; Cell Line; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1973 |
36 other studies available for quinacrine and Chromosomal Triplication
| Article | Year |
|---|---|
Differential nuclear fluorescence during the cell cycle.
Topics: Autoradiography; Cell Line; Chromatin; Embryo, Mammalian; Female; Fibroblasts; HeLa Cells; Humans; M | 1975 |
Trisomy 22. Two new cases and delineation of the phenotype.
Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and | 1975 |
Hot spots and functional organization of human chromosomes.
Topics: Abortion, Spontaneous; Chromosomes; Chromosomes, Human; Crossing Over, Genetic; Female; Genes; Human | 1978 |
Trisomy 9p and unusual translocation mongolism in siblings due to different 3:1 segregations of maternal translocation rcp(9;21)(p11;q11).
Topics: Adolescent; Adult; Azure Stains; Child, Preschool; Chromosomes; Chromosomes, Human, 21-22 and Y; Chr | 1978 |
Chromosome studies of the transplantable Shay chloroleukemia in rats.
Topics: Animals; Chromosome Aberrations; Chromosome Deletion; Fluorescent Dyes; Leukemia, Experimental; Leuk | 1977 |
Cebocephaly in an infant with trisomy 18.
Topics: Brain; Chromosomes, Human; Chromosomes, Human, 16-18; Cytological Techniques; Eye Abnormalities; Gen | 1977 |
Reproducible chromosome changes of polycyclic hydrocarbon-induced rat leukemia: incidence and chromosome banding pattern.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anemia; Animals; Benz(a)Anthracenes; Chromosome Aberrations; Femal | 1978 |
Patau's syndrome and 13q21q translocation.
Topics: Azure Stains; Chromosomes; Chromosomes, Human, 13-15; Chromosomes, Human, 21-22 and Y; Humans; Infan | 1978 |
Family studies on esterase D and chromosome 13 in man.
Topics: Chromosomes; Chromosomes, Human, 13-15; Esterases; Female; Genes; Genetic Linkage; Humans; Male; Qui | 1976 |
Recent advances in the cytogenetic study of human spontaneous abortions.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Chromo | 1975 |
Distinguishing between the chromosomes involved in Down's syndrome (trisomy 21) and cronic myeloid leukaemia (Ph1) by fluorescence.
Topics: Chromosomes; Chromosomes, Human, 21-22 and Y; Down Syndrome; Female; Fluorescent Dyes; Humans; Karyo | 1971 |
A strongly fluorescing abnormal chromosome in a malformed child.
Topics: Abnormalities, Multiple; Child; Chromosome Aberrations; Female; Fluorescence; Humans; Quinacrine; Se | 1971 |
[Fluorography of human chromosomes. A photoelectric procedure for the differentiation of somatic metaphase chromosomes through their fluorescence pattern].
Topics: Chromosomes; Chromosomes, Human, 13-15; Chromosomes, Human, 16-18; Chromosomes, Human, 19-20; Chromo | 1971 |
Four patients with trisomy 8 identified by the fluorescence and Giemsa banding techniques.
Topics: Abnormalities, Multiple; Adolescent; Blood Cells; Child; Child, Preschool; Chromosomes, Human, 6-12 | 1972 |
Trisomy for the smallest autosome of the mouse and identification of the T1Wh translocation chromosome.
Topics: Animals; Chromosome Aberrations; Chromosomes; Cleft Palate; Female; Genotype; Hybridization, Genetic | 1972 |
Identification of partial 12 trisomy by quinacrine fluorescence.
Topics: Chromosome Aberrations; Chromosomes, Human, 6-12 and X; Cytogenetics; Dermatoglyphics; Down Syndrome | 1973 |
8-Trisomy in the bone marrow. Report of two cases.
Topics: Adult; Agranulocytosis; Bone Marrow; Chromosomes, Human, 6-12 and X; Female; Humans; Karyotyping; Ma | 1972 |
Segregating reciprocal (4;21) (q21;q21) translocation with proposita trisomic for parts of 4q and 21.
Topics: Abnormalities, Multiple; Amino Acids; Blood Protein Electrophoresis; Body Height; Body Weight; Child | 1973 |
Uses of banding techniques for the identification of human diseases of cytogenetic origin.
Topics: Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Genetic Techniques; Humans; Leukemia | 1973 |
Marker chromosomes in parents of spontaneous abortuses.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-15; C | 1974 |
Possible complex translocation t(9;14;13) (q12;pl?;Q31) in mother of a child with 9-p trisomy syndrome.
Topics: Adult; Autoradiography; Child; Chromosome Aberrations; Chromosomes, Human, 13-15; Chromosomes, Human | 1974 |
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human, | 1974 |
Distinctive fluorescence of quinacrine-labelled human G group chromosomes.
Topics: Chromosomes, Human, 21-22 and Y; Down Syndrome; Fluorescence; Humans; Karyotyping; Male; Quinacrine; | 1971 |
Quinacrine fluorescence patterns of human D group chromosomes.
Topics: Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Down Syndr | 1971 |
Fluorescence of the trisomic chimpanzee chromosomes.
Topics: Animals; Chromosomes; Down Syndrome; Female; Fluorescence; Humans; Karyotyping; Pan troglodytes; Qui | 1974 |
Trisomy 18 with an E-G translocation (46,XY,21-t(21q18q)+). Identification of the component chromosomes by several laboratory techniques.
Topics: Autoradiography; Chromosome Aberrations; Chromosomes, Human, 16-18; Chromosomes, Human, 21-22 and Y; | 1972 |
Partial trisomy of chromosome 11: a case report.
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and | 1973 |
Partial Trisomy 1, Karyotype 46,XY,12-,t(1q,12p)+.
Topics: Abnormalities, Multiple; Adult; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, | 1973 |
[Fluorescence and non-disjonction].
Topics: Chromosomes; Chromosomes, Human, 13-15; Chromosomes, Human, 16-18; Chromosomes, Human, 21-22 and Y; | 1973 |
Trisomy of the short arm of chromosome 8: association with translocation between chromosomes 8 and 22 46,XY,22-,t(8p22q) plus.
Topics: Adult; Autoradiography; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chrom | 1973 |
The production of monosomic-trisomic individuals in Drosophila melanogaster by x-irradiation of immature oocytes.
Topics: Aneuploidy; Animals; Brain; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Drosophila m | 1971 |
Quinacrine mustard fluorescence of human chromosomes: characterization of unusual translocations.
Topics: Adult; Autoradiography; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, 1-3; Ch | 1972 |
Three non-mongoloid patients of similar phenotype with an extra G-like chromosome.
Topics: Abnormalities, Multiple; Autoradiography; Child; Child, Preschool; Chromosome Aberrations; Chromosom | 1972 |
A case of partial 14 trisomy 47,XY,(14q-)+ and translocation t(9p+;14q-) in mother and brother.
Topics: Adult; Blood Group Antigens; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human | 1972 |
[Fluorescence microscopy--a simple test for XYY].
Topics: Cell Nucleus; Child; Humans; Karyotyping; Male; Methods; Microscopy, Fluorescence; Mosaicism; Mouth | 1971 |
Familial translocation involving chromosomes 6, 14 and 20, identified by quinacrine fluorescence.
Topics: Cell Division; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, 13-15; Chromosomes, Hum | 1971 |