quinacrine has been researched along with Carcinoma in 6 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colorectal cancer is the third most common malignancy in the United States." | 5.36 | Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin. ( Agyeman, A; DeVecchio, J; Houghton, JA; Jani, TS; Mazumdar, T, 2010) |
| "Colorectal cancer is the third most common malignancy in the United States." | 1.36 | Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin. ( Agyeman, A; DeVecchio, J; Houghton, JA; Jani, TS; Mazumdar, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jani, TS | 1 |
| DeVecchio, J | 1 |
| Mazumdar, T | 1 |
| Agyeman, A | 1 |
| Houghton, JA | 1 |
| WIENER, E | 1 |
| ACEL, H | 1 |
| MCKIBBIN, B | 1 |
| GAZET, J | 1 |
| HOPPE, E | 1 |
| SCHWAB, C | 1 |
| ACKERMAN, NB | 1 |
| SHEMESH, A | 1 |
| Kivi, S | 1 |
| Mikelsaar, AV | 1 |
| Atkin, NB | 1 |
6 other studies available for quinacrine and Carcinoma
| Article | Year |
|---|---|
Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin.
Topics: Antineoplastic Agents; Carcinoma; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor | 2010 |
[A new contribution to the treatment of advanced inoperable carcinoma: preliminary report].
Topics: Carcinoma; Humans; Immunotherapy, Active; Neoplasms; Quinacrine | 1959 |
CHEMICAL IRRIGATION OF WOUNDS INOCULATED WITH CANCER CELLS.
Topics: Acridines; Animals; Carcinoma; Carcinoma 256, Walker; Chloramines; Quinacrine; Rats; Research; Surgi | 1963 |
LOCALIZATION OF AMINOACRIDINE FLUORESCENCE IN LUNG TUMORS OF RATS.
Topics: Acridines; Aminacrine; Aminoacridines; Animals; Carcinoma; Carcinoma 256, Walker; Carcinoma, Hepatoc | 1964 |
Q- and C-band polymorphisms in patients with ovarian or breast carcinoma.
Topics: Adult; Aged; Azure Stains; Breast Neoplasms; Carcinoma; Chromosome Banding; Chromosomes, Human; Fema | 1980 |
Y bodies and similar fluorescent chromocentres in human tumours including teratomata.
Topics: Adenocarcinoma; Carcinoma; Colonic Neoplasms; Dysgerminoma; Female; Humans; Male; Microscopy, Fluore | 1973 |