quinacrine has been researched along with Carcinoma, Ehrlich Tumor in 11 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A study of spectra recorded from cultured Ehrlich ascites (EL2), and Harding Passey melanoma cells (HPM-67 and HPM-73 line) grown under comparable conditions, shows that free NAD(P)H predominates in HPM-67 and EL2, while this coenzyme is bound in HPM-73." | 3.66 | The effect of atebrine and an acridine analog (BCMA) on the coenzyme fluorescence spectra of cultured melanoma and Ehrlich ascites (EL2) cells. ( Kohen, C; Kohen, E; Leising, HB; Marty, A; Salmon, JM; Schachtschabel, DO; Thorell, B; Viallet, P, 1978) |
| "Quinacrine is an antimalarial drug that was repositioned for treatment of cancer." | 1.56 | Lactoferrin/Hyaluronic acid double-coated lignosulfonate nanoparticles of quinacrine as a controlled release biodegradable nanomedicine targeting pancreatic cancer. ( Abdallah, OY; Elnaggar, YSR; Etman, SM; Mehanna, RA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Etman, SM | 1 |
| Abdallah, OY | 1 |
| Mehanna, RA | 1 |
| Elnaggar, YSR | 1 |
| Pfab, R | 2 |
| Schachtschabel, DO | 3 |
| Paul, N | 1 |
| Biller, H | 2 |
| Hess, F | 2 |
| Yamamoto, S | 1 |
| Kawasaki, T | 1 |
| Leising, HB | 2 |
| Christensen, HN | 2 |
| Viallet, P | 1 |
| Kohen, E | 1 |
| Marty, A | 1 |
| Salmon, JM | 1 |
| Kohen, C | 1 |
| Thorell, B | 1 |
| Garcia-Sancho, J | 1 |
| Sanchez, A | 1 |
| Handlogten, ME | 1 |
| Grunicke, H | 1 |
| Doppler, W | 1 |
| Hofmann, J | 1 |
| Lindner, H | 1 |
| Maly, K | 1 |
| Oberhuber, H | 1 |
| Ringsdorf, H | 1 |
| Roberts, JJ | 1 |
| von Ardenne, M | 1 |
| Reitnauer, PG | 1 |
| Anghileri, LJ | 1 |
| Fekete, I | 1 |
| Serfözö, JI | 1 |
11 other studies available for quinacrine and Carcinoma, Ehrlich Tumor
| Article | Year |
|---|---|
Lactoferrin/Hyaluronic acid double-coated lignosulfonate nanoparticles of quinacrine as a controlled release biodegradable nanomedicine targeting pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Movement; Cell Surv | 2020 |
[Ultrastructural studies on the effect of roentgen rays and quinacrine (atebrin)--alone or in combination--on Ehrlich ascites tumor cells in monolayer culture].
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytoskeleton; Endoplasmic Reticulum; Mice; Micro | 1983 |
The involvement of the membrane oxidoreduction system in stimulating amino acid uptake in Ehrlich ascites tumor cells.
Topics: Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Ascorbic Acid; Biological Trans | 1981 |
[Intensification of the inhibitory effect of X-rays on the growth of Ehrlich ascites tumor cells in monolayer culture by quinacrine (atebrine) or chloroquine (resochine) (author's transl)].
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Chloroquine; Quinacrine; Radiothe | 1980 |
Amino acid transport systems in animal cells: interrelations and energization.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Ascorbic Acid; Bacteria; Biological Transport, Active; | 1977 |
The effect of atebrine and an acridine analog (BCMA) on the coenzyme fluorescence spectra of cultured melanoma and Ehrlich ascites (EL2) cells.
Topics: Acridines; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; DNA, Neoplasm; Melanoma; NAD | 1978 |
Unexpected additional mode of energization of amino-acid transport into Ehrlich cells.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Azides; Biological Transport, Active; Carcinoma, Ehrli | 1977 |
Plasma membrane as target of alkylating agents.
Topics: Adenosine Triphosphatases; Alkylating Agents; Animals; Calcium Channel Blockers; Carcinoma 256, Walk | 1985 |
[Thermosensitization of mouse Ehrlich ascites tumor cells using atebrin].
Topics: Adaptation, Physiological; Animals; Carcinoma, Ehrlich Tumor; Hot Temperature; Humans; Malaria; Mice | 1968 |
Uptake of iodine-131-labelled atabrine by Ehrlich ascites tumour and by sarcoma S-180 BALB.
Topics: Animals; Carcinoma, Ehrlich Tumor; Iodine Isotopes; Liver; Mice; Muscles; Quinacrine; Sarcoma 180; S | 1966 |
[Metabolism of glucose, fructose, and mannose in Ehrlich ascites carcinoma cells].
Topics: Acridines; Animals; Carcinoma, Ehrlich Tumor; Fructose; Glucose; Glycolysis; Mannose; Quinacrine; Qu | 1966 |