quinacrine has been researched along with Cancer of the Uterus in 5 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute quinacrine toxicity was evident during the dosing period but did not affect long-term survival." | 1.36 | A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats. ( Bolte, HF; Cancel, AM; Creasy, DM; Dillberger, JE; Kelly, CM; Sokal, DC, 2010) |
| "Cohort study." | 1.31 | Cancer risk among women sterilized with transcervical quinacrine in Chile: an update through 1996. ( Dabancens, A; Guzman-Serani, R; Sokal, DC; Zipper, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haseman, JK | 1 |
| Growe, RG | 2 |
| Zeiger, E | 2 |
| McConnell, EE | 2 |
| Luster, MI | 2 |
| Lippes, J | 2 |
| Cancel, AM | 1 |
| Dillberger, JE | 1 |
| Kelly, CM | 1 |
| Bolte, HF | 1 |
| Creasy, DM | 1 |
| Sokal, DC | 3 |
| Fail, P | 1 |
| Vach, TH | 1 |
| Nanda, K | 1 |
| McCann, MF | 1 |
| Weiner, DH | 1 |
| Drobnes, C | 1 |
| Rochanawutanon, M | 1 |
| Duc, NB | 1 |
| Loan, ND | 1 |
| Dabancens, A | 1 |
| Guzman-Serani, R | 1 |
| Zipper, J | 1 |
5 other studies available for quinacrine and Cancer of the Uterus
| Article | Year |
|---|---|
A critical examination of the mode of action of quinacrine in the reproductive tract in a 2-year rat cancer bioassay and its implications for human clinical use.
Topics: Animals; Cell Transformation, Neoplastic; Chemistry, Pharmaceutical; Chronic Disease; Contraceptive | 2015 |
A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats.
Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Fallopian Tubes; Female; Longevity; Quinacri | 2010 |
An alternative interpretation of, "A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats".
Topics: Animals; Dose-Response Relationship, Drug; Female; Longevity; Quinacrine; Rats; Rats, Sprague-Dawley | 2010 |
Quinacrine sterilization and gynecologic cancers: a case-control study in northern Vietnam.
Topics: Age Factors; Case-Control Studies; Confidence Intervals; Female; Genital Neoplasms, Female; Humans; | 2010 |
Cancer risk among women sterilized with transcervical quinacrine in Chile: an update through 1996.
Topics: Adult; Breast Neoplasms; Cervix Uteri; Cohort Studies; Female; Follow-Up Studies; Humans; Neoplasms; | 2000 |