quinacrine has been researched along with Cancer of Mouth in 5 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Herein, using in vitro oral squamous cell carcinoma (OSCC) CSCs and in vivo xenograft mice model, we have systematically studied the apoptotic potentiality of quinacrine-gold hybrid nanoparticle (QAuNP) and its underlying mechanism after NIR irradiation." | 1.72 | NIR irradiation enhances the apoptotic potentiality of quinacrine-gold hybrid nanoparticles by modulation of HSP-70 in oral cancer stem cells. ( Chatterjee, S; Das, B; Dash, SR; Kundu, CN; Panda, R; Paul, S; Pradhan, R; Sethy, C; Sinha, S; Tripathy, J, 2022) |
| "Complete eradication of aggressive oral cancer remains a challenge due to the presence of CSCs." | 1.48 | Metallic gold and bioactive quinacrine hybrid nanoparticles inhibit oral cancer stem cell and angiogenesis by deregulating inflammatory cytokines in p53 dependent manner. ( Das, S; Kundu, CN; Nayak, A; Nayak, D; Satapathy, SR; Siddharth, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dash, SR | 1 |
| Chatterjee, S | 1 |
| Sinha, S | 1 |
| Das, B | 1 |
| Paul, S | 1 |
| Pradhan, R | 1 |
| Sethy, C | 2 |
| Panda, R | 1 |
| Tripathy, J | 1 |
| Kundu, CN | 4 |
| Nayak, A | 3 |
| Siddharth, S | 3 |
| Das, S | 2 |
| Nayak, D | 2 |
| Satapathy, SR | 2 |
| Das, D | 1 |
| López-Jornet, P | 1 |
| Pons-Fuster, A | 1 |
5 other studies available for quinacrine and Cancer of Mouth
| Article | Year |
|---|---|
NIR irradiation enhances the apoptotic potentiality of quinacrine-gold hybrid nanoparticles by modulation of HSP-70 in oral cancer stem cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Gold; Humans; | 2022 |
Nanoquinacrine caused apoptosis in oral cancer stem cells by disrupting the interaction between GLI1 and β catenin through activation of GSK3β.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Dose-Response Relationship, Drug; | 2017 |
Metallic gold and bioactive quinacrine hybrid nanoparticles inhibit oral cancer stem cell and angiogenesis by deregulating inflammatory cytokines in p53 dependent manner.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cytokines; Gene Ex | 2018 |
Enhancement of Cytotoxicity and Inhibition of Angiogenesis in Oral Cancer Stem Cells by a Hybrid Nanoparticle of Bioactive Quinacrine and Silver: Implication of Base Excision Repair Cascade.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Chick Embryo; Chorioallantoic Membran | 2015 |
Pigmented oral mucosa due to quinacrine.
Topics: Antimalarials; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Cutaneous; Melanoma; Mi | 2011 |