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quinacrine and Brain Edema

quinacrine has been researched along with Brain Edema in 1 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koide, T1
Asano, T1
Matsushita, H1
Takakura, K1

Other Studies

1 other study available for quinacrine and Brain Edema

ArticleYear
Enhancement of ATPase activity by a lipid peroxide of arachidonic acid in rat brain microvessels.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Arachidonic Acids; Brain; Brain Edema; Ca(2+) Mg(2+)-ATPase; Dos

1986