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quinacrine and Bonnevie-Ullrich Syndrome

quinacrine has been researched along with Bonnevie-Ullrich Syndrome in 13 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Bonnevie-Ullrich Syndrome: This syndrome that was originally observed by Ullrich, and designated as identical to TURNER SYNDROME, related the webbing of the neck, loose skin and other anomalies of the syndrome to accumulation of fluid in the embryo starting at the head and dispersing to the extremities (as observed by Bonnevie in mice). Commonly observed at birth in Turner Syndrome and NOONAN SYNDROME; EDEMA of the extremities usually recedes by one year and is an early sign of Turner syndrome, especially in female neonates.

Research Excerpts

ExcerptRelevanceReference
"A patients with seizures, Von Willebrand disease, and symptoms of Turner syndrome was a chromosomal mosaic."1.26Structure and Barr body formation of an Xp + chromosome with two inactivation centers. ( Daly, RF; Patau, K; Sarto, GE; Therman, E, 1977)
"She is the sixth reported monosomy X patient to achieve pregnancy."1.26Pregnancy and the Turner syndrome. ( Bennett, S; King, CR; Magenis, E, 1978)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199013 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayek, A1
Yunis, E1
Kulikov, RI1
Mashkova, MV1
Verlinskaia, DK1
Bondarev, GN1
Daly, RF1
Patau, K1
Therman, E1
Sarto, GE1
Hsu, LY1
Paciuc, S1
David, K1
Cristian, S1
Moloshok, R1
Hirschhorn, K1
King, CR1
Magenis, E1
Bennett, S1
Coco, R1
Bergada, C1
Paulson, JD1
Keller, DW1
Muhlendorf, K1
Eatherly, C1
Distèche, C1
Hagemeijer, A1
Frederic, J1
Progneaux, D1
De la Chapelle, A1
Stenstrand, K1
Bühler, EM1
Bühler, UK1
Tsuchimoto, T1
Stalder, GR1
Breg, WR1
Caspersson, T1
Lindsten, J1
Zech, L1
Mende, S1
Alonso, A1

Other Studies

13 other studies available for quinacrine and Bonnevie-Ullrich Syndrome

ArticleYear
Dicentric Y chromosome in mixed gonadal dysgenesis.
    Journal of medical genetics, 1975, Volume: 12, Issue:2

    Topics: Adolescent; Chromosomes; Disorders of Sex Development; Dysgerminoma; Female; Humans; Karyotyping; Ly

1975
[Identification of several chromosome aberrations in man by the fluorescent method using quinacrine yprite].
    Tsitologiia, 1976, Volume: 18, Issue:2

    Topics: Adolescent; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytodiagnosis; Disorders

1976
Structure and Barr body formation of an Xp + chromosome with two inactivation centers.
    American journal of human genetics, 1977, Volume: 29, Issue:1

    Topics: Adolescent; Female; Humans; Mosaicism; Quinacrine; Seizures; Sex Chromatin; Sex Chromosome Aberratio

1977
Number of C-bands of human isochromosome Xqi and relation to 45,X mosaicism.
    Journal of medical genetics, 1978, Volume: 15, Issue:3

    Topics: Azure Stains; Chromosome Aberrations; Female; Humans; Karyotyping; Mosaicism; Quinacrine; Sex Chromo

1978
Pregnancy and the Turner syndrome.
    Obstetrics and gynecology, 1978, Volume: 52, Issue:5

    Topics: Adult; Chromosome Banding; Congenital Abnormalities; Female; Humans; Infant, Newborn; Karyotyping; M

1978
Cytogenetic findings in 125 patients with Turner's syndrome and abnormal karyotypes.
    Journal de genetique humaine, 1977, Volume: 25, Issue:2

    Topics: Acridines; Azure Stains; Bromodeoxyuridine; Chromosome Aberrations; Female; Humans; Karyotyping; Mat

1977
A rapid screening technic for detection of Y chromosomes.
    Obstetrics and gynecology, 1976, Volume: 48, Issue:6

    Topics: Amenorrhea; Cytogenetics; Female; Fluorescent Dyes; Humans; Karyotyping; Leukocytes; Male; Methods;

1976
An abnormal large human chromosome identified as an end-to-end fusion of two X's by combined results of the new banding techniques and microdensitometry.
    Clinical genetics, 1972, Volume: 3, Issue:5

    Topics: Abnormalities, Multiple; Adolescent; Blood; Chromosome Aberrations; Chromosome Disorders; Chromosome

1972
Dicentric human X chromosomes.
    Hereditas, 1974, Volume: 76, Issue:2

    Topics: Chromosome Aberrations; Female; Fluorescent Dyes; Heterochromatin; Humans; Karyotyping; Lymphocytes;

1974
Non-fluorescent Y-chromosome.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:5

    Topics: Adolescent; Autoradiography; Body Height; Body Weight; Child; Chromosome Aberrations; Chromosomes, H

1974
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
    Birth defects original article series, 1974, Volume: 10, Issue:8

    Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human,

1974
The nature of structural X chromosome aberrations in Turner's syndrome as revealed by quinacrine mustard fluorescence analysis.
    Hereditas, 1970, Volume: 66, Issue:2

    Topics: Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-15; Chromosomes,

1970
[Determination of male nuclear sex in human blood cells].
    Deutsche medizinische Wochenschrift (1946), 1971, Jun-25, Volume: 96, Issue:26

    Topics: Adult; Eosinophils; Female; Humans; Karyotyping; Leukocytes; Lymphocytes; Male; Microscopy, Fluoresc

1971