quinacrine has been researched along with Bipolar Disorder in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report the case of a 20-year-old man who presented with a de novo episode of hypomania subsequent to the initiation of quinacrine for treatment resistant giardiasis." | 3.78 | Quinacrine induced mood disturbance--the unmasking of bipolar affective disorder. ( Byrne, F; Lally, J; Walsh, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lally, J | 1 |
| Byrne, F | 1 |
| Walsh, E | 1 |
| ALLIEZ, J | 1 |
| SAVY, A | 1 |
| Grudev, FI | 1 |
| Moreno, TJ | 1 |
| Green, J | 1 |
4 other studies available for quinacrine and Bipolar Disorder
| Article | Year |
|---|---|
Quinacrine induced mood disturbance--the unmasking of bipolar affective disorder.
Topics: Adult; Antiprotozoal Agents; Bipolar Disorder; Giardiasis; Humans; Male; Quinacrine; Young Adult | 2012 |
[Symptomatic manias and recent therapies].
Topics: Adrenocorticotropic Hormone; Amphetamine; Amphetamines; Bipolar Disorder; Cortisone; Humans; Mental | 1954 |
[Experience with the use of acrichine in patients in depressive states and catatonis(preliminary report)].
Topics: Adjustment Disorders; Adolescent; Adult; Antidepressive Agents; Bipolar Disorder; Catatonia; Chlorpr | 1966 |
Quinacrine-associated mania.
Topics: Adult; Bipolar Disorder; Female; Humans; Quinacrine | 1989 |