quinacrine has been researched along with Bacillus anthracis Infection in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, animals dosed with human equivalent doses of quinacrine were not protected against respiratory spore challenge." | 1.33 | Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames. ( Chatuev, BM; Chopra, AK; Comer, JE; McHenry, DJ; Noffsinger, DM; Peterson, JW; Weisbaum, DM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Comer, JE | 1 |
| Noffsinger, DM | 1 |
| McHenry, DJ | 1 |
| Weisbaum, DM | 1 |
| Chatuev, BM | 1 |
| Chopra, AK | 1 |
| Peterson, JW | 1 |
| Shin, S | 1 |
| Kim, YB | 1 |
| Hur, GH | 1 |
2 other studies available for quinacrine and Bacillus anthracis Infection
| Article | Year |
|---|---|
Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames.
Topics: Administration, Intranasal; Animals; Anthrax; Bacillus anthracis; Bioterrorism; Disease Models, Anim | 2006 |
Involvement of phospholipase A2 activation in anthrax lethal toxin-induced cytotoxicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminobenzoic Acid; Acetophenones; Aminobenzoates; A | 1999 |