quinacrine has been researched along with Autosomal Chromosome Disorders in 62 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The total incidence of major chromosome aberrations including numerical changes of the sex chromosomes, and structural changes of autosomes, was 0." | 1.26 | Chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique. ( Gedeon, MM; Griffith, P; Lin, CC; Newton, DR; Sewell, LM; Smink, WK; Wilkie, L, 1976) |
| "Chromosomal abnormalities were detected in 59% of the specimens." | 1.25 | Recent advances in the cytogenetic study of human spontaneous abortions. ( Carr, DH; McConnell, HD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fowler, G | 1 |
| Kaiser-McCaw, B | 1 |
| Hecht, F | 4 |
| Verma, RS | 1 |
| Dosik, H | 1 |
| Penchaszadeh, VB | 1 |
| Coco, R | 1 |
| Gutierrez, AC | 1 |
| Salamanca, F | 1 |
| Lisker, R | 1 |
| Segovia, A | 1 |
| Kulikov, RI | 1 |
| Mashkova, MV | 1 |
| Verlinskaia, DK | 1 |
| Bondarev, GN | 1 |
| Lin, CC | 1 |
| Gedeon, MM | 1 |
| Griffith, P | 1 |
| Smink, WK | 1 |
| Newton, DR | 1 |
| Wilkie, L | 1 |
| Sewell, LM | 1 |
| Fraccaro, M | 1 |
| Zuffardi, O | 1 |
| Buhler, EM | 1 |
| Jurik, LP | 1 |
| Garson, OM | 1 |
| Bocian, M | 2 |
| Mohandas, T | 1 |
| Noël, B | 2 |
| Ayraud, N | 1 |
| Levy, M | 1 |
| Cau, D | 1 |
| McConnell, HD | 1 |
| Carr, DH | 1 |
| Naritomi, K | 1 |
| Hirayama, K | 1 |
| Nielsen, H | 1 |
| Skakkebaek, NE | 1 |
| Philip, J | 1 |
| Retief, AE | 1 |
| van Niekerk, WA | 1 |
| Franceschini, P | 1 |
| Fabris, C | 1 |
| Bogetti, G | 1 |
| Santoro, MA | 1 |
| Chaippo, G | 1 |
| Yanagisawa, S | 1 |
| Distèche, C | 1 |
| Hagemeijer, A | 1 |
| Frederic, J | 1 |
| Progneaux, D | 1 |
| Peterson, WD | 1 |
| Simpson, WF | 1 |
| Ecklund, PS | 1 |
| Stulberg, CS | 1 |
| Magenis, RE | 3 |
| McCaw, BK | 1 |
| Caspersson, T | 2 |
| Lindsten, J | 2 |
| Lomakka, G | 1 |
| Moller, A | 1 |
| Zech, L | 3 |
| Miller, OJ | 3 |
| Miller, DA | 3 |
| Warburton, D | 1 |
| Baserga, A | 1 |
| Castoldi, GL | 1 |
| Rowley, JD | 1 |
| Jacobsen, P | 1 |
| Mikkelsen, M | 1 |
| Rosleff, F | 1 |
| Zeuthen, E | 1 |
| Nielsen, J | 2 |
| De la Chapelle, A | 1 |
| Koivisto, M | 1 |
| Schröder, J | 1 |
| Hreidarsson, AB | 1 |
| Christensen, KR | 1 |
| Shaw, MW | 1 |
| Porter, IH | 1 |
| McKusick, VA | 1 |
| Chase, GA | 1 |
| del Solar, C | 1 |
| Uchida, IA | 1 |
| Mitelman, F | 1 |
| Hsia, YE | 1 |
| Appadorai, V | 1 |
| Breg, WR | 5 |
| Howard, RO | 1 |
| Allderdice, PW | 1 |
| Warren, RJ | 1 |
| Rimoin, DL | 1 |
| Summitt, RL | 1 |
| Toomey, K | 1 |
| Bartuska, D | 1 |
| Alderdice, PW | 1 |
| Armendares, S | 1 |
| Weleber, RG | 1 |
| Overton, K | 1 |
| Atkins, L | 1 |
| Miller, WL | 1 |
| Salam, M | 1 |
| Baughman, FA | 1 |
| Mann, JD | 1 |
| Borgaonkar, DS | 1 |
| Ebenezer, L | 1 |
| Scott, CI | 1 |
| Golomb, HM | 1 |
| Bahr, GF | 1 |
| Falk, RE | 1 |
| Carrel, RE | 1 |
| Valente, M | 1 |
| Crandall, BF | 2 |
| Sparkes, RS | 1 |
| Van den Berghe, H | 1 |
| Fryns, JP | 1 |
| David, G | 1 |
| Rosenthal, IM | 1 |
| Krmpotic, E | 1 |
| Szego, K | 1 |
| Mayeda, K | 1 |
| Weiss, L | 1 |
| Lindahl, R | 1 |
| Dully, M | 1 |
| Traut, H | 1 |
| Scheid, W | 1 |
| Becker, KL | 1 |
| Schnedl, W | 1 |
| Gustavson, KH | 1 |
| Hitrec, V | 1 |
| Santesson, B | 1 |
| Weber, F | 1 |
| Muller, HM | 1 |
| Burwell, JK | 1 |
| Reiss, JA | 1 |
| Wyandt, HE | 1 |
| Lovrien, EW | 1 |
| Short, EM | 1 |
| Solitare, GB | 1 |
| Emerit, I | 1 |
| Luciani, JM | 1 |
| Quack, B | 1 |
| Berger, R | 1 |
| Gagné, R | 1 |
| Francke, U | 1 |
| Nesbitt, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomised Multicentre Phase IV Study to Compare Glivec® (Imatinib Mesylate, STI571) in Monotherapy Versus Glivec® in Combination With Interferon Alpha at Low Doses in the Treatment of Newly-Diagnosed Chronic-Phase Chronic Myeloid Leukaemia[NCT00390897] | Phase 4 | 360 participants | Interventional | 2003-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for quinacrine and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Chromosome-banding techniques and their implication in hematology.
Topics: Acute Disease; Azure Stains; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Ban | 1979 |
The use of fluorescence techniques for the recognition of mammalian chromosomes and chromosome regions.
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Chromosomes, Human, 16-18; Chrom | 1972 |
Application of new staining techniques to the study of human chromosomes.
Topics: Base Sequence; Burkitt Lymphoma; Cell Line; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1973 |
The Philadelphia chromosome.
Topics: Alkaline Phosphatase; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; | 1973 |
Human genetics.
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Chromosomes; Crossing Ove | 1973 |
57 other studies available for quinacrine and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
The use of sequential silver and quinacrine staining to determine the parental origin and breakpoints of a ring-22 human chromosome.
Topics: Abnormalities, Multiple; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome D | 1980 |
Heteromorphisms of the Philadelphia (Ph1) chromosome in patients with chronic melogenous leukaemia (CML). I. Classification and clinical significance.
Topics: Acridine Orange; Aged; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y | 1980 |
Trisomy 22. Two new cases and delineation of the phenotype.
Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and | 1975 |
Supernumerary bisatellited chromosome in a family ascertained through a patient with Sturge-Weber syndrome.
Topics: Angiomatosis; Cells, Cultured; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Fluor | 1975 |
[Identification of several chromosome aberrations in man by the fluorescent method using quinacrine yprite].
Topics: Adolescent; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytodiagnosis; Disorders | 1976 |
Chromosome analysis on 930 consecutive newborn children using quinacrine fluorescent banding technique.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes, Human, 1-3; Chromos | 1976 |
15/15 translocation in Prader-Willi syndrome.
Topics: Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human; Chromosomes, Human, 13-15; | 1977 |
Recent cytogenetic advances and implications for pediatric practice.
Topics: Abortion, Spontaneous; Azure Stains; Chromosome Aberrations; Chromosome Banding; Chromosome Disorder | 1978 |
[Cat eye syndrome: chromosome study and genetic counseling].
Topics: Adult; Aneuploidy; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Col | 1976 |
Recent advances in the cytogenetic study of human spontaneous abortions.
Topics: Abortion, Spontaneous; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Chromo | 1975 |
Determination of the breakpoints and the parental origin of a ring 22 chromosome: an analysis by high-resolution banding technique, quinacrine and silver stainings.
Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Chromosom | 1988 |
Dyeing the Y chromosome.
Topics: Acridines; Animals; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Flavins; Fluorescence; | 1971 |
[Fluorescence microscopy of Y chromatin. A method for the study of Y-chromosome abnormalities].
Topics: Amnion; Chromosome Aberrations; Chromosome Disorders; Fibroblasts; Humans; Lymphocytes; Male; Method | 1971 |
[A new technic for the analysis of human chromosomes].
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Cytogenetics; Female; Fluorescent Antibod | 1971 |
[Value of the use of fluorescent substances in the study of normal and pathologic human karyotypes. I. Identification of the Y chromosome].
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Fluorescence; Humans; Karyotyping; Method | 1972 |
Immunoglobulin abnormality in a girl with a large chromosome 18.
Topics: Adolescent; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 16-18; Dermatog | 1972 |
An abnormal large human chromosome identified as an end-to-end fusion of two X's by combined results of the new banding techniques and microdensitometry.
Topics: Abnormalities, Multiple; Adolescent; Blood; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1972 |
Diploid and heteroploid human cell lines surveyed for Y chromosome fluorescence.
Topics: Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Chromosome Diso | 1973 |
Clinical cytogenetics. Dawn breaks on a new era.
Topics: Child; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Female; Humans; Infant, Newborn; | 1973 |
Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.
Topics: Adolescent; Adult; Aged; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1973 |
A ring chromosome, diagnosed by quinacrine fluorescence as No. 9, in a mentally retarded girl.
Topics: Adult; Amino Acids; Body Height; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6 | 1973 |
D-D translocations in males examined for military service.
Topics: Adult; Body Height; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Denmark | 1973 |
Segregating reciprocal (4;21) (q21;q21) translocation with proposita trisomic for parts of 4q and 21.
Topics: Abnormalities, Multiple; Amino Acids; Blood Protein Electrophoresis; Body Height; Body Weight; Child | 1973 |
D-D translocations in patients with mental illness.
Topics: Adolescent; Adult; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; F | 1973 |
Uses of banding techniques for the identification of human diseases of cytogenetic origin.
Topics: Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Genetic Techniques; Humans; Leukemia | 1973 |
Human cytogenetics: trends and techniques.
Topics: Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Chromosomes; Cyto | 1973 |
Identification of chromosomal abnormalities by quinacrine-staining technique in patients with normal karyotypes by conventional analysis.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1974 |
Heterogeneity of Ph1 in chronic myeloid leukaemia.
Topics: Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Ch | 1974 |
Chromosomal abnormality (46,XX,3p plus) in a case of the Meckel syndrome.
Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Chro | 1974 |
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human, | 1974 |
Quinacrine fluorescence patterns of human D group chromosomes.
Topics: Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Down Syndr | 1971 |
Identification by fluorescent microscopy of the abnormal chromosomes associated with the G-deletion syndromes.
Topics: Blepharoptosis; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes, | 1973 |
Clinical application of fluorescent staining of chromosomes.
Topics: Alkylating Agents; Chromosome Aberrations; Chromosome Disorders; Female; Fluoresceins; Fluorescence; | 1973 |
Quinacrine fluorescence patterns and terminal DNA labelling of human C group chromosomes.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and X; DNA; Female; Fluoresce | 1972 |
Identification by fluorescence of two G rings: (46,XY,21r) G deletion syndrome I and (46, XX, 22r) G deletion syndrome II.
Topics: Abnormalities, Multiple; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and | 1972 |
A ring-20 chromosome.
Topics: Child; Child Behavior Disorders; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1 | 1972 |
Ascertainment of seven YY males in a private neurology practice.
Topics: Adolescent; Adult; Antisocial Personality Disorder; Child, Preschool; Chromosome Aberrations; Chromo | 1972 |
Identification of a D-E(15-18) translocation chromosome by quinacrine fluorescence and urea banding techniques.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Chromosomes, Human, 16-18; | 1973 |
Partial trisomy of chromosome 11: a case report.
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and | 1973 |
Renovascular hypertension. Prospective diagnostic yield in a random access population.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 1-3; Fluorescence; Humans; Hypogon | 1973 |
A (15;18) translocation, unbalanced, 45 chromosomes. Human Genetic Mutant Cell Repository, Camden, N.J., identification No. GM-17.
Topics: Cells, Cultured; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, | 1973 |
Trisomy of the short arm of chromosome 8: association with translocation between chromosomes 8 and 22 46,XY,22-,t(8p22q) plus.
Topics: Adult; Autoradiography; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chrom | 1973 |
Localization of the human lactate dehydrogenase B gene on the short arm of chromosome 12.
Topics: Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Ch | 1974 |
The production of monosomic-trisomic individuals in Drosophila melanogaster by x-irradiation of immature oocytes.
Topics: Aneuploidy; Animals; Brain; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Drosophila m | 1971 |
The human karyotype.
Topics: Chromosome Aberrations; Chromosome Disorders; Humans; Karyotyping; Methods; Microscopy, Fluorescence | 1972 |
[The atebrin fluorescence method in human cytogenetics].
Topics: Chromosome Aberrations; Chromosome Disorders; Cytogenetics; Female; Fluorescence; Fluorescent Dyes; | 1972 |
Three non-mongoloid patients of similar phenotype with an extra G-like chromosome.
Topics: Abnormalities, Multiple; Autoradiography; Child; Child, Preschool; Chromosome Aberrations; Chromosom | 1972 |
Identification of 21r and 22r chromosomes by quinacrine fluorescence.
Topics: Abnormalities, Multiple; Adult; Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Ch | 1972 |
Mosaicism with translocation: autoradiographic and fluorescent studies of an inherited reciprocal translocation t(2q+;14q-).
Topics: Abnormalities, Multiple; Adult; Aneuploidy; Autoradiography; Blood Group Antigens; Child; Chromosome | 1972 |
A case of partial 14 trisomy 47,XY,(14q-)+ and translocation t(9p+;14q-) in mother and brother.
Topics: Adult; Blood Group Antigens; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human | 1972 |
A familial Y-autosome translocation in man.
Topics: Adolescent; Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15 | 1971 |
[Constitutional chromosome abnormalities].
Topics: Chromosome Aberrations; Chromosome Disorders; Cytogenetics; DNA; Fluoresceins; Humans; Karyotyping; | 1971 |
[New perspectives in human cytogenetics].
Topics: Acridines; Chromosome Aberrations; Chromosome Disorders; Cytogenetics; DNA; Humans; Methods; Nucleic | 1971 |
The identification of human chromosomes by fluorescence technics.
Topics: Animals; Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Crossing Over, | 1971 |
Cattanach's translocation: cytological characterization by quinacrine mustard staining.
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Female; Fluorescence; Genetic Linkage; Hetero | 1971 |
Identification of the abnormal B group chromosome in the "cri du chat" syndrome by QM-fluorescence.
Topics: Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 4-5; Cri-du-Chat | 1970 |
Chromosome identification.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Female; Humans; Male; Methods; Microscopy | 1971 |