quinacrine has been researched along with Arthritis, Rheumatoid in 19 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Many of these reviews, while generally excellent, have propagated some apparent misconceptions by disregarding or de-emphasizing data suggesting that irreversible retinal toxicity due to antimalarials can be easily avoided by judicious daily dosage and regular ophthalmologic follow-up." | 2.36 | Antimalarials and ophthalmologic safety. ( Olansky, AJ, 1982) |
| "The drugs used in the treatment of rheumatoid arthritis are divided into two classes: a "first aid" and a "back up" group." | 1.27 | [Synthetic antimalarials in the therapy of rheumatoid arthritis: adverse effects and advantages]. ( Lanciani, P, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ADAR, U | 1 |
| OKA, MJ | 1 |
| FORESTIER, J | 1 |
| CERTONCINY, A | 1 |
| ESCARPENTER-ORIOL, J | 1 |
| BAYES, C | 1 |
| GOMEZ, MS | 1 |
| ERLENDSSON, F | 2 |
| CARRERAS BAYES, A | 1 |
| ESCARPENTER ORIOL, J | 1 |
| SARIOLS GOMEZ, M | 1 |
| ENGESET, A | 2 |
| HANSSEN, P | 1 |
| NEILSON, N | 1 |
| LANSBURY, J | 1 |
| VERHAEGHE, A | 1 |
| LEBEURRE, R | 1 |
| DARNET, C | 1 |
| TUFFANELLI, D | 1 |
| ABRAHAM, RK | 1 |
| DUBOIS, EI | 1 |
| FREEDMAN, A | 1 |
| BACH, F | 1 |
| Olansky, AJ | 1 |
| Fahey, JV | 1 |
| Newcombe, DS | 1 |
| Egorin, MJ | 1 |
| Trump, DL | 1 |
| Wainwright, CW | 1 |
| Lanciani, P | 1 |
| Brynolf, I | 1 |
| Biro, L | 1 |
| Leone, N | 1 |
1 review available for quinacrine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Antimalarials and ophthalmologic safety.
Topics: Antimalarials; Arthritis, Rheumatoid; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, | 1982 |
18 other studies available for quinacrine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
The treatment of rheumatoid arthritis with mepacrine.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Quinacrine | 1953 |
Treatment of rheumatoid arthritis with atebrin.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Quinacrine | 1953 |
[Serological research in chronic inflammatory rheumatism; study of antistreptolysin O].
Topics: Antistreptolysin; Arthritis, Rheumatoid; Chloroquine; Chronic Disease; Humans; Quinacrine; Research; | 1954 |
[Atebrin and resochin treatment in progressive chronic polyarthritis].
Topics: Arthritis; Arthritis, Rheumatoid; Chloroquine; Humans; Quinacrine | 1955 |
[Mepacrine therapy of chronic polyarthritis].
Topics: Arthritis; Arthritis, Rheumatoid; Quinacrine | 1955 |
[Antimalarial drugs in therapy of chronic evolutive polyarthritis].
Topics: Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Humans; Quinacrine | 1955 |
Mepacrine and rheumatoid arthritis; preliminary communication.
Topics: Arthritis; Arthritis, Rheumatoid; Communication; Humans; Quinacrine | 1956 |
Treatment of rheumatoid arthritis with quinacrine and chloroquine.
Topics: Arthritis; Arthritis, Rheumatoid; Chloroquine; Humans; Quinacrine | 1958 |
[Long term treatment of rheumatoid arthritis with mepacrine & chloroquine].
Topics: Arthritis; Arthritis, Rheumatoid; Chloroquine; Humans; Long-Term Care; Quinacrine | 1958 |
A study of the mechanism by which quinacrine inhibits L.E. cell formation.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Leukocytes; Neutrophils; Quinacrine | 1961 |
[Report on the use, in the treatment of chronic evolutive polyarthritis, of a drug combining notably 2 synthetic antimalarials].
Topics: Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Humans; Quinacrine | 1963 |
PIGMENTATION FROM ANTIMALARIAL THERAPY. ITS POSSIBLE RELATIONSHIP TO THE OCULAR LESIONS.
Topics: Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Cornea; Eye; Eye Manifestations; Histo | 1963 |
Mepacrine and rheumatoid arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Quinacrine | 1952 |
Regulation of bradykinin-induced cyclic amp response by quinacrine and prostaglandin E2 and F2 alpha in human synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Bradykinin; Cells, Cultured; Cyclic AMP; Drug Synergism; Fibroblasts; Humans; | 1979 |
Quinacrine ochronosis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Ochronosis; Quinacrine | 1976 |
[Synthetic antimalarials in the therapy of rheumatoid arthritis: adverse effects and advantages].
Topics: Arthritis, Rheumatoid; Chloroquine; Drug Evaluation; Enzyme Inhibitors; Histamine H1 Antagonists; Hu | 1985 |
Pigmentation of the hard and solf palate in a patient with rheumatoid arthritis treated with an antimalarial (triquin).
Topics: Arthritis, Rheumatoid; Biopsy; Chloroquine; Female; Humans; Middle Aged; Palate; Pigmentation Disord | 1970 |
Aplastic anemia induced by quinacrine.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; | 1965 |