quinacrine has been researched along with Anthrax in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Anthrax: An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, animals dosed with human equivalent doses of quinacrine were not protected against respiratory spore challenge." | 1.33 | Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames. ( Chatuev, BM; Chopra, AK; Comer, JE; McHenry, DJ; Noffsinger, DM; Peterson, JW; Weisbaum, DM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Comer, JE | 1 |
| Noffsinger, DM | 1 |
| McHenry, DJ | 1 |
| Weisbaum, DM | 1 |
| Chatuev, BM | 1 |
| Chopra, AK | 1 |
| Peterson, JW | 1 |
| Shin, S | 1 |
| Kim, YB | 1 |
| Hur, GH | 1 |
2 other studies available for quinacrine and Anthrax
| Article | Year |
|---|---|
Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames.
Topics: Administration, Intranasal; Animals; Anthrax; Bacillus anthracis; Bioterrorism; Disease Models, Anim | 2006 |
Involvement of phospholipase A2 activation in anthrax lethal toxin-induced cytotoxicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminobenzoic Acid; Acetophenones; Aminobenzoates; A | 1999 |