Page last updated: 2024-10-16

quinacrine and Anasarca

quinacrine has been researched along with Anasarca in 10 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Research Excerpts

ExcerptRelevanceReference
" africana was examined for topical antiinflammatory activity and proved to be active against arachidonic acid (AA) acute edema, 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced chronic inflammation, and oxazolone delayed-type hypersensitivity in mice."3.69Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark. ( Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL, 1997)
"Oedema was maximal within 1 h after BJV injection, was partially reduced at 6 h and disappeared completely within 24 h."1.28Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom. ( Calixto, JB; Trebien, HA, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cuéllar, MJ1
Giner, RM1
Recio, MC1
Just, MJ1
Máñez, S1
Cerdá, M1
Hostettmann, K1
Ríos, JL1
REESE, FM1
CHAMBERLAIN, WP1
BOLES, DJ1
Hanna, PC1
Kruskal, BA1
Ezekowitz, RA1
Bloom, BR1
Collier, RJ1
Higgs, GA1
Harvey, EA1
Ferreira, SH1
Vane, JR1
Moreno, JJ1
Ferrer, X1
Ortega, E1
Carganico, G1
Trebien, HA1
Calixto, JB1
Yoshioka, A1
Miyachi, Y1
Imamura, S1
Freeman, RG1
Knox, JM1
Owens, DW1

Other Studies

10 other studies available for quinacrine and Anasarca

ArticleYear
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
    Journal of natural products, 1997, Volume: 60, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibi

1997
Edema of the corneal epithelium caused by atabrine; observation on three patients.
    Bulletin of the Johns Hopkins Hospital, 1946, Volume: 78

    Topics: Edema; Epithelium, Corneal; Quinacrine

1946
CORNEAL edema; unusual toxic reaction to atabrine.
    Bulletin of the U.S. Army Medical Department. United States. Army. Medical Department, 1946, Volume: 5

    Topics: Corneal Edema; Edema; Postoperative Complications; Quinacrine

1946
Edema of cornea precipitated by quinacrine (atabrine).
    Archives of ophthalmology (Chicago, Ill. : 1929), 1946, Volume: 35

    Topics: Cornea; Corneal Diseases; Disease; Edema; Quinacrine

1946
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
    Molecular medicine (Cambridge, Mass.), 1994, Volume: 1, Issue:1

    Topics: Animals; Antigens, Bacterial; Antioxidants; Ascorbic Acid; Bacillus anthracis; Bacterial Toxins; Cel

1994
The effects of antiinflammatory drugs on the production of prostaglandins in vivo.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Movement; Colchicine;

1976
PLA2-induced oedema in rat skin and histamine release in rat mast cells. Evidence for involvement of lysophospholipids in the mechanism of action.
    Agents and actions, 1992, Volume: 36, Issue:3-4

    Topics: Animals; Aristolochic Acids; Cytoplasmic Granules; Dexamethasone; Edema; Histamine Release; In Vitro

1992
Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom.
    Agents and actions, 1989, Volume: 26, Issue:3-4

    Topics: Animals; Captopril; Crotalid Venoms; Dexamethasone; Edema; Hot Temperature; Indomethacin; Male; Maso

1989
The mechanism of the inhibitory effects of antimalarials on UV-induced skin inflammation in mice.
    The Journal of dermatology, 1988, Volume: 15, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chloroquine; Ear, External; Edema; Female; Inflammatio

1988
Cutaneous lesions of lupus erythematosus induced by monochromatic light.
    Archives of dermatology, 1969, Volume: 100, Issue:6

    Topics: Acanthosis Nigricans; Edema; Erythema; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Sy

1969