Page last updated: 2024-10-16

quinacrine and Aging

quinacrine has been researched along with Aging in 8 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"We describe cumulative pregnancy probabilities among women who underwent quinacrine pellet sterilization in Chile between 1977 and 1989 (N = 1492)."7.70Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989. ( Feldblum, PJ; Guzman-Serani, R; Hays, M; Sokal, DC; Zipper, J, 2000)
"We describe cumulative pregnancy probabilities among women who underwent quinacrine pellet sterilization in Chile between 1977 and 1989 (N = 1492)."3.70Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989. ( Feldblum, PJ; Guzman-Serani, R; Hays, M; Sokal, DC; Zipper, J, 2000)
"Quinacrine was found to ameliorate the skewed sex ratio but did not affect non-disjunction."1.29Ageing before mating and quinacrine ameliorate the expression of abnormal oocyte (abo) in homozygous Drosophila melanogaster females. ( Magnusson, J; Onfelt, A; Wikén, M, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nurse, CA2
Macintyre, L1
Diamond, J2
Heimpel, H1
Heit, W1
Onfelt, A1
Magnusson, J1
Wikén, M1
Hansson, SR1
Hoffman, BJ1
Feldblum, PJ1
Hays, M1
Zipper, J1
Guzman-Serani, R1
Sokal, DC1
Mills, LR1
Pierre, RV1
Hoagland, HC1
Chen, TR1
Ruddle, FH1
Stulberg, CS1

Reviews

1 review available for quinacrine and Aging

ArticleYear
Drug-induced aplastic anaemia: clinical aspects.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici

1980

Other Studies

7 other studies available for quinacrine and Aging

ArticleYear
A quantitative study of the time course of the reduction in Merkel cell number within denervated rat touch domes.
    Neuroscience, 1984, Volume: 11, Issue:2

    Topics: Aging; Animals; Denervation; Microscopy, Electron; Microscopy, Fluorescence; Quinacrine; Rats; Skin;

1984
Ageing before mating and quinacrine ameliorate the expression of abnormal oocyte (abo) in homozygous Drosophila melanogaster females.
    Hereditas, 1993, Volume: 118, Issue:1

    Topics: Aging; Animals; Drosophila melanogaster; Female; Gene Expression; Male; Mutation; Nondisjunction, Ge

1993
Transient expression of a functional serotonin transporter in Merkel cells during late gestation and early postnatal rat development.
    Experimental brain research, 2000, Volume: 130, Issue:3

    Topics: Aging; Animals; Carrier Proteins; Cells, Cultured; Embryonic and Fetal Development; Fluoxetine; Gene

2000
Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989.
    Contraception, 2000, Volume: 61, Issue:6

    Topics: Adult; Aging; Chile; Cohort Studies; Female; Humans; Pregnancy; Pregnancy Outcome; Pregnancy, Ectopi

2000
The neural dependency of Merkel cell development in the rat: the touch domes and foot pads contrasted.
    Developmental biology, 1989, Volume: 136, Issue:1

    Topics: Aging; Animals; Denervation; Foot; Mechanoreceptors; Microscopy, Electron; Microscopy, Fluorescence;

1989
Age-associated aneuploidy: loss of Y chromosome from human bone marrow cells with aging.
    Cancer, 1972, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Aneuploidy; Bone Marrow Cells; Child; Child, Preschool; Chromosomes;

1972
Chromosome changes revealed by the Q-band staining method during cell senescence of WI-38.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 147, Issue:2

    Topics: Aging; Animals; Cell Line; Chromosome Aberrations; Diploidy; Fibroblasts; Karyotyping; Mice; Quinacr

1974