quinacrine and Aging
quinacrine has been researched along with Aging in 8 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe cumulative pregnancy probabilities among women who underwent quinacrine pellet sterilization in Chile between 1977 and 1989 (N = 1492)." | 7.70 | Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989. ( Feldblum, PJ; Guzman-Serani, R; Hays, M; Sokal, DC; Zipper, J, 2000) |
| "We describe cumulative pregnancy probabilities among women who underwent quinacrine pellet sterilization in Chile between 1977 and 1989 (N = 1492)." | 3.70 | Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989. ( Feldblum, PJ; Guzman-Serani, R; Hays, M; Sokal, DC; Zipper, J, 2000) |
| "Quinacrine was found to ameliorate the skewed sex ratio but did not affect non-disjunction." | 1.29 | Ageing before mating and quinacrine ameliorate the expression of abnormal oocyte (abo) in homozygous Drosophila melanogaster females. ( Magnusson, J; Onfelt, A; Wikén, M, 1993) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nurse, CA | 2 |
| Macintyre, L | 1 |
| Diamond, J | 2 |
| Heimpel, H | 1 |
| Heit, W | 1 |
| Onfelt, A | 1 |
| Magnusson, J | 1 |
| Wikén, M | 1 |
| Hansson, SR | 1 |
| Hoffman, BJ | 1 |
| Feldblum, PJ | 1 |
| Hays, M | 1 |
| Zipper, J | 1 |
| Guzman-Serani, R | 1 |
| Sokal, DC | 1 |
| Mills, LR | 1 |
| Pierre, RV | 1 |
| Hoagland, HC | 1 |
| Chen, TR | 1 |
| Ruddle, FH | 1 |
| Stulberg, CS | 1 |
Reviews
1 review available for quinacrine and Aging
| Article | Year |
|---|---|
Drug-induced aplastic anaemia: clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici | 1980 |
Other Studies
7 other studies available for quinacrine and Aging
| Article | Year |
|---|---|
A quantitative study of the time course of the reduction in Merkel cell number within denervated rat touch domes.
Topics: Aging; Animals; Denervation; Microscopy, Electron; Microscopy, Fluorescence; Quinacrine; Rats; Skin; | 1984 |
Ageing before mating and quinacrine ameliorate the expression of abnormal oocyte (abo) in homozygous Drosophila melanogaster females.
Topics: Aging; Animals; Drosophila melanogaster; Female; Gene Expression; Male; Mutation; Nondisjunction, Ge | 1993 |
Transient expression of a functional serotonin transporter in Merkel cells during late gestation and early postnatal rat development.
Topics: Aging; Animals; Carrier Proteins; Cells, Cultured; Embryonic and Fetal Development; Fluoxetine; Gene | 2000 |
Pregnancy rates among Chilean women who had non-surgical sterilization with quinacrine pellets between 1977 and 1989.
Topics: Adult; Aging; Chile; Cohort Studies; Female; Humans; Pregnancy; Pregnancy Outcome; Pregnancy, Ectopi | 2000 |
The neural dependency of Merkel cell development in the rat: the touch domes and foot pads contrasted.
Topics: Aging; Animals; Denervation; Foot; Mechanoreceptors; Microscopy, Electron; Microscopy, Fluorescence; | 1989 |
Age-associated aneuploidy: loss of Y chromosome from human bone marrow cells with aging.
Topics: Adolescent; Adult; Aged; Aging; Aneuploidy; Bone Marrow Cells; Child; Child, Preschool; Chromosomes; | 1972 |
Chromosome changes revealed by the Q-band staining method during cell senescence of WI-38.
Topics: Aging; Animals; Cell Line; Chromosome Aberrations; Diploidy; Fibroblasts; Karyotyping; Mice; Quinacr | 1974 |