quinacrine has been researched along with Adenocarcinoma of Lung in 1 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Adenocarcinoma of Lung: A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine has been used for therapeutic drugs in some clinical settings." | 5.46 | Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand. ( Harada, M; Hiramatsu, R; Kataoka, T; Kondo, T; Matsuda, I; Morimoto, K; Muko, R; Okina, Y, 2017) |
| "Quinacrine has been used for therapeutic drugs in some clinical settings." | 1.46 | Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand. ( Harada, M; Hiramatsu, R; Kataoka, T; Kondo, T; Matsuda, I; Morimoto, K; Muko, R; Okina, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, M | 1 |
| Morimoto, K | 1 |
| Kondo, T | 1 |
| Hiramatsu, R | 1 |
| Okina, Y | 1 |
| Muko, R | 1 |
| Matsuda, I | 1 |
| Kataoka, T | 1 |
1 other study available for quinacrine and Adenocarcinoma of Lung
| Article | Year |
|---|---|
Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Proliferation; Cell | 2017 |