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quinacrine and Abnormalities, Sex Chromosome

quinacrine has been researched along with Abnormalities, Sex Chromosome in 47 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Research Excerpts

ExcerptRelevanceReference
"A patients with seizures, Von Willebrand disease, and symptoms of Turner syndrome was a chromosomal mosaic."1.26Structure and Barr body formation of an Xp + chromosome with two inactivation centers. ( Daly, RF; Patau, K; Sarto, GE; Therman, E, 1977)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199047 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daly, RF1
Patau, K1
Therman, E1
Sarto, GE1
Frey, RO1
Bühler, EM1
Bühler, UK1
Stalder, GR1
Xamena, N1
Creus, A1
Velázquez, A1
Marcos, R1
Singer, R1
Joshua, H1
Hazaz, B1
Sagiv, M1
Laner, H1
Levinsky, H1
Servadio, C1
Atkin, NB1
Lewin, PK2
Vakil, DV1
Conen, PE3
Sumner, AT1
Robinson, JA2
Evans, HJ1
Thuline, HC1
Dallapiccola, B1
Asaka, A1
Kegel, J1
Fründ, S1
Koske-Westphal, T2
Fuchs-Mecke, S2
Passarge, E2
Lamborot-Manzur, M2
Tishler, PV2
Atkins, L2
Kardon, NB1
Chernay, PR1
Hsu, LY1
Martin, JL1
Hirschhorn, K1
Alam, MT1
Deschamps, R1
Gaba, E1
Kasatiya, SS1
Grant, WF1
Schoepflin, GS1
Centerwall, WR1
Hellweg-Fründ, S1
Caspersson, T2
Lindsten, J2
Lomakka, G1
Moller, A1
Zech, L2
Miller, OJ1
Miller, DA1
Warburton, D1
Shaw, MW1
Porter, IH1
De la Chapelle, A3
Stenstrand, K1
Friedrich, U2
Nielsen, J1
De Chieri, PR1
Albores, JM1
Weitzel, H1
Schwinger, E1
Kowalska, E1
Wiśniewski, L1
Holbek, S1
Lauritsen, JG1
Therkelsen, J1
Breg, WR1
Pearson, PL2
Bobrow, M2
Vosa, CG1
Lo Curto, F1
Scappaticci, S1
Zuffardi, O1
Chierichetti, G1
Fraccaro, M1
Kasdan, R1
Nankin, HR1
Troen, P1
Wald, N1
Pan, S1
Yanaihara, T1
Fabris, C1
Franceschini, P1
Bogetti, G1
Ponzone, A1
Kovàcs, M1
Sellyei, M1
Szabò, A1
Vass, L1
Wilson, MG1
Towner, JW1
Lipshin, J1
Fleisher, A1
Meisner, LF1
Inhorn, SL1
Noel, B1
Emerit, I1
Luciani, JM1
Quack, B1
Schröder, J2
Kaski, U1
Forsius, H1
Chandley, AC1
Edmond, P1
Buckton, KE1
Pike, MC1
el-Alfi, OS1
Deminatti, M1
Savary, JB1
Polani, PE1
Mutton, DE1
Mende, S1
Alonso, A1

Reviews

2 reviews available for quinacrine and Abnormalities, Sex Chromosome

ArticleYear
The use of fluorescence techniques for the recognition of mammalian chromosomes and chromosome regions.
    International review of experimental pathology, 1972, Volume: 11

    Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Chromosomes, Human, 16-18; Chrom

1972
Application of new staining techniques to the study of human chromosomes.
    Progress in medical genetics, 1973, Volume: 9

    Topics: Base Sequence; Burkitt Lymphoma; Cell Line; Chromosome Aberrations; Chromosome Disorders; Chromosome

1973

Other Studies

45 other studies available for quinacrine and Abnormalities, Sex Chromosome

ArticleYear
Structure and Barr body formation of an Xp + chromosome with two inactivation centers.
    American journal of human genetics, 1977, Volume: 29, Issue:1

    Topics: Adolescent; Female; Humans; Mosaicism; Quinacrine; Seizures; Sex Chromatin; Sex Chromosome Aberratio

1977
[45,X/46,SYq dic-Sexchromosome mosaic].
    Humangenetik, 1975, Volume: 27, Issue:2

    Topics: Adult; Blood Cells; Cells, Cultured; Child; Female; Fibroblasts; Fluorescence; Hair; Humans; Hypogon

1975
Testing of chloroquine and quinacrine for mutagenicity in Drosophila melanogaster.
    Mutation research, 1985, Volume: 158, Issue:3

    Topics: Animals; Chloroquine; Drosophila melanogaster; Genes, Lethal; Genes, Recessive; Male; Mutagenicity T

1985
Lack of correlation between human y-positive spermatozoa and acrosomal abnormalities and variations in intensity of fluorescence of sperm stained with quinacrine compounds.
    Archives of andrology, 1985, Volume: 15, Issue:1

    Topics: Acrosome; Fluorescent Dyes; Humans; Male; Microscopy, Fluorescence; Oligospermia; Quinacrine; Quinac

1985
Y chromosomes and quinacrine fluorescence technique.
    British medical journal, 1970, Oct-10, Volume: 4, Issue:5727

    Topics: Adult; Female; Humans; Male; Microscopy, Fluorescence; Middle Aged; Pregnancy; Quinacrine; Sex Chrom

1970
Dyeing the Y chromosome.
    Lancet (London, England), 1971, Feb-06, Volume: 1, Issue:7693

    Topics: Acridines; Animals; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Flavins; Fluorescence;

1971
Dyeing the Y chromosome.
    Lancet (London, England), 1971, Mar-20, Volume: 1, Issue:7699

    Topics: Coloring Agents; Fluorescent Dyes; Humans; Quinacrine; Sex Chromosome Aberrations; Sex Chromosomes

1971
Distingiishing between X, Y and YY-bearing human spermatozoa by fluorescence and DNA content.
    Nature: New biology, 1971, Feb-24, Volume: 229, Issue:8

    Topics: Cytogenetics; DNA; Fluorescence; Genetics, Medical; Histocytochemistry; Humans; Male; Methods; Quina

1971
Y-specific fluorescence in peripheral blood leukocytes.
    The Journal of pediatrics, 1971, Volume: 78, Issue:5

    Topics: Female; Fluorescence; Humans; Hydrochloric Acid; Karyotyping; Leukocytes; Male; Methods; Quinacrine;

1971
Identification of the human sex chromosome complement in polymorphonuclear leukocytes: a new technique.
    The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:1

    Topics: Female; Humans; Klinefelter Syndrome; Leukocytes; Male; Methods; Quinacrine; Sex Chromatin; Sex Chro

1971
Fluorescent Y screening of hospitalized newborns.
    Nature, 1971, Oct-01, Volume: 233, Issue:5318

    Topics: Chromosomes, Human, 21-22 and Y; Congenital Abnormalities; Fluorescence; Hospitalization; Humans; In

1971
Quinacrine fluorescent survey of Japanese juvenile delinquents.
    Lancet (London, England), 1972, Feb-05, Volume: 1, Issue:7745

    Topics: Fluoresceins; Humans; Japan; Juvenile Delinquency; Quinacrine; Sex Chromosome Aberrations

1972
Nuclear sex identification in human tissues: a histologic study using quinacrine fluorescence.
    American journal of clinical pathology, 1972, Volume: 57, Issue:4

    Topics: Adenocarcinoma; Autopsy; Cytogenetics; Female; Fluorescence; Gastric Mucosa; Humans; Male; Methods;

1972
Quinacrine mustard fluorescence of a second Y chromosome in a Y-autosomal translocation.
    Humangenetik, 1972, Volume: 14, Issue:2

    Topics: Cell Division; Cheek; Chromosome Aberrations; Chromosomes, Human, 13-15; Chromosomes, Human, 21-22 a

1972
Quantitative studies of Y chromosomal fluorescence in human interphase nuclei.
    Clinical genetics, 1972, Volume: 3, Issue:2

    Topics: Adult; Aneuploidy; Carcinoma, Bronchogenic; Chromosome Aberrations; Female; Fluorescence; Humans; In

1972
Polymorphism of the human Y chromosomes: fluorescence microscopic studies on the sites of morphologic variation.
    Clinical genetics, 1972, Volume: 3, Issue:2

    Topics: Chromosome Aberrations; Fluorescence; Genotype; Humans; Karyotyping; Lymphocytes; Male; Methods; Mic

1972
Problems in prenatal diagnosis resulting from chromosomal mosaicism.
    Clinical genetics, 1972, Volume: 3, Issue:2

    Topics: Abortion, Therapeutic; Adult; Amniocentesis; Amniotic Fluid; Female; Fetus; Gestational Age; Humans;

1972
The XYY syndrome in an adolescent male exhibiting prominent behavioral problems.
    Clinical genetics, 1972, Volume: 3, Issue:3

    Topics: Adolescent; Body Height; Chromosome Aberrations; Dermatoglyphics; Electroencephalography; Female; Fl

1972
48,XYYY: a new syndrome?
    Journal of medical genetics, 1972, Volume: 9, Issue:3

    Topics: Bone Diseases, Developmental; Bone Marrow Cells; Child; Dermatoglyphics; Diagnosis, Differential; He

1972
[Identification of Y-chromosome anomalies using fluorescence microscopy. Study on 2 groups of prisoners as a contribution to the XYY problem].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-27, Volume: 97, Issue:43

    Topics: Adult; Aged; Chromosome Aberrations; Female; Fibroblasts; Germany, West; Humans; Karyotyping; Male;

1972
Uses of banding techniques for the identification of human diseases of cytogenetic origin.
    Environmental health perspectives, 1973, Volume: 6

    Topics: Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Genetic Techniques; Humans; Leukemia

1973
Human cytogenetics: trends and techniques.
    Progress in clinical pathology, 1973, Volume: 5

    Topics: Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Chromosomes; Cyto

1973
Dicentric human X chromosomes.
    Hereditas, 1974, Volume: 76, Issue:2

    Topics: Chromosome Aberrations; Female; Fluorescent Dyes; Heterochromatin; Humans; Karyotyping; Lymphocytes;

1974
Pericentric inversion Y in a population of newborn boys.
    Hereditas, 1974, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Child; Chromosome Aberrations; Female; Humans; Infant, Newborn; Karyotyping; Male

1974
[Identification of the XYY syndrome by quinacrine dihydrochloride fluorescence staining].
    Medicina, 1974, Volume: 34, Issue:2

    Topics: Adult; Fluorescent Dyes; Humans; Karyotyping; Male; Methods; Microscopy, Fluorescence; Mitosis; Quin

1974
[Present status of prenatal sex-diagnosis (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1974, Volume: 178, Issue:3

    Topics: Amniocentesis; Amniotic Fluid; Cells, Cultured; Cervix Mucus; Diagnostic Errors; Evaluation Studies

1974
[Fluorescence diagnosis of sex chromosomes in the XYY syndrome].
    Zeitschrift fur Hautkrankheiten, 1974, Jul-01, Volume: 49, Issue:13

    Topics: Blood Cells; Humans; Karyotyping; Leukocytes; Male; Methods; Microscopy, Fluorescence; Mouth Mucosa;

1974
Marker chromosomes in parents of spontaneous abortuses.
    Humangenetik, 1974, Volume: 25, Issue:1

    Topics: Abortion, Spontaneous; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-15; C

1974
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
    Birth defects original article series, 1974, Volume: 10, Issue:8

    Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human,

1974
Technique for identifying Y chromosomes in human interphase nuclei.
    Nature, 1970, Apr-04, Volume: 226, Issue:5240

    Topics: Acridines; Cell Nucleus; Cheek; Cytogenetics; Fibroblasts; Humans; Lymphocytes; Male; Methods; Micro

1970
Non-fluorescent Y chromosome in a 45,X-46,XY mosaic.
    Annales de genetique, 1972, Volume: 15, Issue:2

    Topics: Adolescent; Autoradiography; Chromosome Aberrations; Female; Fluorescence; Heterochromatin; Humans;

1972
Paternal transmission of maleness in XX human beings.
    The New England journal of medicine, 1973, Mar-15, Volume: 288, Issue:11

    Topics: Adult; Androgens; Child; Child, Preschool; Disorders of Sex Development; Female; Fibroblasts; Fluore

1973
Sex chromosome anomalies detection and fluorescence.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Autoradiography; Cell Division; Cell Line; Fluorescence; Genitalia, Male; Humans; Infant; Male; Meth

1973
Occurrence of XYY individuals among juvenile delinquents in Hungary.
    Humangenetik, 1973, Mar-23, Volume: 18, Issue:1

    Topics: Cell Nucleus; Cells, Cultured; Humans; Hungary; Juvenile Delinquency; Karyotyping; Lymphocytes; Male

1973
Identification of an unusual Y chromosome in YY mosaicism by quinacrine fluorescence.
    Nature, 1971, Jun-11, Volume: 231, Issue:5302

    Topics: Child, Preschool; Female; Fibroblasts; Humans; In Vitro Techniques; Microscopy, Fluorescence; Mosaic

1971
Normal male development with Y chromosome long arm deletion (Yq-).
    Journal of medical genetics, 1972, Volume: 9, Issue:3

    Topics: Adult; Diagnosis, Differential; Fertility; Humans; Intellectual Disability; Karyotyping; Male; Micro

1972
A familial Y-autosome translocation in man.
    Clinical genetics, 1971, Volume: 2, Issue:1

    Topics: Adolescent; Autoradiography; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15

1971
[Fluorescence microscopy--a simple test for XYY].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:21

    Topics: Cell Nucleus; Child; Humans; Karyotyping; Male; Methods; Microscopy, Fluorescence; Mosaicism; Mouth

1971
Meiotic studies on a subfertile patient with a ring Y chromosome.
    Cytogenetics, 1971, Volume: 10, Issue:4

    Topics: Adult; Biopsy; Blood Cells; Humans; Infertility, Male; Karyotyping; Male; Meiosis; Microscopy; Micro

1971
Quinacrine fluorescence of variant and abnormal human Y chromosomes.
    Chromosoma, 1971, Volume: 35, Issue:3

    Topics: Cell Nucleus; Cells, Cultured; Chromosome Aberrations; Female; Fluorescence; Genetic Variation; Huma

1971
Length variation in the quinacrine-binding segment of human Y chromosomes of different sizes.
    Cytogenetics, 1971, Volume: 10, Issue:3

    Topics: Chromatin; Fluorescence; Genetic Variation; Humans; Infertility, Male; Klinefelter Syndrome; Male; Q

1971
[Human amniotic cells: study of X and Y sex chromatins].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1971, Volume: 16, Issue:8

    Topics: Amniotic Fluid; Female; Fluorescence; Humans; Pregnancy; Quinacrine; Sex Chromatin; Sex Chromosome A

1971
Absence of brightly fluorescent Y material in XX men.
    Annales de genetique, 1971, Volume: 14, Issue:3

    Topics: Cytogenetics; Fluorescence; Humans; Karyotyping; Male; Methods; Mustard Plant; Plants, Medicinal; Qu

1971
Y-fluorescence of interphase nuclei, especially circulating lymphocytes.
    British medical journal, 1971, Jan-16, Volume: 1, Issue:5741

    Topics: Amniotic Fluid; Female; Fetus; Fibroblasts; Fluorescence; Humans; Klinefelter Syndrome; Lymphocytes;

1971
[Determination of male nuclear sex in human blood cells].
    Deutsche medizinische Wochenschrift (1946), 1971, Jun-25, Volume: 96, Issue:26

    Topics: Adult; Eosinophils; Female; Humans; Karyotyping; Leukocytes; Lymphocytes; Male; Microscopy, Fluoresc

1971