quetiapine-fumarate and Tardive-Dyskinesia

We describe the case of a 12-year-old boy that developed invalidating motor symptoms after starting and gradually increasing the dose of quetiapine with extended release and phasing out aripiprazole. The symptoms met the definition of tardive dyskinesia given their duration and presentation. Symptoms decreased spontaneously after discontinuation of neuroleptic treatment. The literature and knowledge among clinicians concerning the occurrence of tardive dyskinesia in children and adolescents treated with atypical antipsychotics are limited. We give an overview of the available scientific findings with special attention to the presentation, the incidence and treatment possibilities.

Topics: Antipsychotic Agents; Aripiprazole; Child; Dyskinesia, Drug-Induced; Humans; Male; Quetiapine Fumarate; Tardive Dyskinesia

Topics: Antipsychotic Agents; Diabetes Mellitus; Humans; Psychotic Disorders; Quetiapine Fumarate; Renal Insufficiency, Chronic; Tardive Dyskinesia