quercetin-3-o-glucuronide and Cognitive-Dysfunction

quercetin-3-o-glucuronide has been researched along with Cognitive-Dysfunction* in 1 studies

Other Studies

1 other study(ies) available for quercetin-3-o-glucuronide and Cognitive-Dysfunction

ArticleYear
Quercetin-3-O-Glucuronide Alleviates Cognitive Deficit and Toxicity in Aβ
    Molecular nutrition & food research, 2021, Volume: 65, Issue:6

    Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) related imbalance, Tau-hyperphosphorylation, and neuroinflammation, in which Aβ and neuroinflammation can induce brain insulin resistance (IR). Gut microbiome disorder is correlated with inflammation in AD. As of yet, there are no effective treatments clinically. Thus, it is focused on the potential benefit of quercetin-3-O-glucuronide (Q3G), a pharmacologically active flavonol glucuronide, on AD treatment by regulating brain IR and the gut microbiome.. AD mice model built through intracerebroventricular injection of Aβ. Q3G can alleviate brain IR through directly acting on the brain or modulating the gut-brain axis, ultimately to relieve Aβ

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Cognitive Dysfunction; Disease Models, Animal; Gastrointestinal Microbiome; Hippocampus; Humans; Insulin Resistance; Male; Memory Disorders; Mice, Inbred C57BL; Neuroblastoma; Neurons; Neuroprotective Agents; Peptide Fragments; Quercetin; tau Proteins

2021