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pyruvic acid and Thiamine Deficiency

pyruvic acid has been researched along with Thiamine Deficiency in 32 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)

Research Excerpts

ExcerptRelevanceReference
"Long-term thiamine deficiency has been largely documented, whilst little is known about effects of short-term depletion/repletion periods on thiamine vitamers status."3.74Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model. ( Batifoulier, F; Besson, C; Chanliaud, E; Demigné, C; Rémésy, C; Verny, MA, 2007)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199025 (78.13)18.7374
1990's2 (6.25)18.2507
2000's2 (6.25)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sweet, RL1
Zastre, JA1
Shibata, K1
Nakata, C1
Fukuwatari, T1
Jankowska-Kulawy, A1
Bielarczyk, H1
Pawełczyk, T1
Wróblewska, M1
Szutowicz, A1
van HEERSWYNGHELS, J1
THOMAS, J1
DE CARO, L2
CASELLA, C1
RINDI, G4
TURNOCK, DM1
WELBOURN, RB1
FERRARI, G3
PERRI, V2
WRIGHT, RC1
SCOTT, EM1
FRANKEN, JF1
STAPERT, FP1
JACKSON, FL1
DE CARO, LG1
APPANNA, TC1
KOEPPE, RE1
O'NEAL, RM1
HAHN, CH1
Jones, JH1
De Angeli, E1
OSHIMA, T1
HAYASHI, J1
MAEKAWA, A1
ITO, K1
SUZUKI, T1
SAHASHI, Y1
Dabak, M1
Gul, Y1
FORNAROLI, P1
Batifoulier, F1
Verny, MA1
Besson, C1
Chanliaud, E1
Rémésy, C1
Demigné, C1
HORWITT, MK1
KREISLER, O1
DAVENPORT, HW1
JONES, B1
Gorbach, ZV1
Maglysh, SS1
Ostrovskiĭ, IuM1
Lee, CM1
Moyo, EN1
Aboko-Cole, GF1
Baines, M1
Lubek, BM1
Mainwood, GW1
Gibson, G1
Barclay, L1
Blass, J1
Edwin, EE1
Jackman, R1
Munujos, P1
Coll-Cantí, J1
Beleta, J1
González-Sastre, F1
Gella, FJ1
Rathanaswami, P1
Pourany, A1
Sundaresan, R1
Elnageh, KM1
Gaitonde, MK1

Reviews

1 review available for pyruvic acid and Thiamine Deficiency

ArticleYear
The role of the cholinergic system in thiamin deficiency.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylcholine; Aging; Animals; Arecoline; Atropine; Behavior, Animal; Brain; Diet

1982

Trials

1 trial available for pyruvic acid and Thiamine Deficiency

ArticleYear
Thiamine deficiency in sheep with chronic rumen acidosis.
    The Veterinary record, 2004, Jan-10, Volume: 154, Issue:2

    Topics: Acidosis; Animal Feed; Animal Husbandry; Animals; Chronic Disease; Lactates; Pyruvic Acid; Rumen; Sh

2004

Other Studies

30 other studies available for pyruvic acid and Thiamine Deficiency

ArticleYear
HIF1-α-mediated gene expression induced by vitamin B1 deficiency.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2013, Volume: 83, Issue:3

    Topics: Cell Hypoxia; Cell Nucleus; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid;

2013
High-performance liquid chromatographic method for profiling 2-oxo acids in urine and its application in evaluating vitamin status in rats.
    Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:2

    Topics: Adipates; Animals; Biomarkers; Chromatography, High Pressure Liquid; Hemiterpenes; Keto Acids; Ketog

2016
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex;

2010
Variations in glycogen and pyruvic acid in the heart during the electrocardiographic changes observed in avitaminosis B1 in rats; role of pyruvic acid.
    Cardiologia, 1945, Volume: 9, Issue:3-4

    Topics: Heart; Myocardium; Pyruvic Acid; Thiamine; Thiamine Deficiency

1945
Respiratory quotient, heat production and blood pyruvic acid in aneurin deficient rats after glucose administration.
    Experientia, 1952, Nov-15, Volume: 8, Issue:11

    Topics: Animals; Body Temperature; Cell Respiration; Glucose; Pyruvates; Pyruvic Acid; Rats; Respiration; Th

1952
The effects of glucose on blood pyruvic acid levels in mild thiamine deficiency.
    The Journal of laboratory and clinical medicine, 1953, Volume: 42, Issue:2

    Topics: Glucose; Humans; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1953
[Correlation between blood pyruvate, tissue thiamine and adrenal hypertrophy in vitamin B1 deficient rats].
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1954, Volume: 25, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Animals; Blood; Hypertrophy; Pyruvates; Pyruvic Acid; Rats;

1954
Pyruvate and alpha-ketoglutarate metabolism in thiamine deficiency.
    The Journal of biological chemistry, 1954, Volume: 206, Issue:2

    Topics: Keto Acids; Ketoglutaric Acids; Ketones; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thiamine; Thi

1954
Restoration of pyruvate breakdown in pigeon muscle homogenates impaired by thiamine deficiency.
    Biochimica et biophysica acta, 1954, Volume: 14, Issue:2

    Topics: Animals; Biochemical Phenomena; Columbidae; Muscles; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Def

1954
[Pyruvate in blood and thiamine in tissues in mice in B1 avitaminosis].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:9

    Topics: Animals; Avitaminosis; Mice; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Deficiency; Vitamin B Defic

1956
Pyruvate accumulation and development of thiamine deficiency in cultures of Proteus vulgaris.
    Journal of general microbiology, 1957, Volume: 16, Issue:3

    Topics: Proteus vulgaris; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1957
[Origin of increased pyruvic acid level of the blood in avitaminosis B1 of rats].
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1958, Volume: 28, Issue:4

    Topics: Animals; Avitaminosis; Pyruvates; Pyruvic Acid; Rats; Thiamine; Thiamine Deficiency; Vitamin B Defic

1958
BLOOD PYRUVIC ACID RESPONSE TO ORAL ADMINISTRATION OF GLUCOSE IN NORMAL AND DISEASED SUBJECTS.
    The Indian journal of medical research, 1964, Volume: 52

    Topics: Administration, Oral; Biomedical Research; Blood; Carbohydrate Metabolism; Diabetes Mellitus; Glucos

1964
PYRUVATE DECARBOXYLATION IN THIAMINE DEFICIENT BRAIN.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: Animals; Brain; Carboxy-Lyases; Coenzyme A; Decarboxylation; Glucose; Glutamates; Poultry; Pyruvates

1964
On the metabolic significance of blood pyruvate in B1 avitaminosis.
    Experientia, 1955, May-15, Volume: 11, Issue:5

    Topics: Adrenal Cortex; Avitaminosis; Blood; Humans; Pituitary Gland; Pyruvates; Pyruvic Acid; Thiamine; Thi

1955
Thiamine deficiency and the in vivo oxidation of lactate and pyruvate labeled with carbon.
    The Journal of nutrition, 1960, Volume: 70

    Topics: Carbon; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Defi

1960
Decrease of apoenzyme activities in vitamin-deficient animals. I. Decrease of pyruvate-apooxidase activity in vitamin B1-deficient rats.
    The Journal of vitaminology, 1960, Jun-10, Volume: 6

    Topics: Animals; Apoenzymes; Oxidoreductases; Pyruvates; Pyruvic Acid; Rats; Thiamine; Thiamine Deficiency;

1960
[Pyruvic acid accumulation in muscles, during activity and during rest, in B1 vitamin deficiency].
    Archivio di fisiologia, 1949, Volume: 49, Issue:1

    Topics: Acids; Biochemical Phenomena; Humans; Muscles; Pyruvic Acid; Rest; Thiamine; Thiamine Deficiency

1949
THIAMINE deficiency, pyruvate metabolism, and acid secretion in stomachs of mice in vitro.
    Nutrition reviews, 1950, Volume: 8, Issue:7

    Topics: Animals; Biological Transport; Humans; In Vitro Techniques; Mice; Pyruvic Acid; Stomach; Thiamine; T

1950
Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2007, Volume: 77, Issue:1

    Topics: Animals; Body Weight; Bread; Cerebellum; Diet; Disease Models, Animal; Glucose; Glutamic Acid; Kidne

2007
The determination of early thiamine-deficient states by estimation of blood lactic and pyruvic acids after glucose administration and exercise.
    The Journal of nutrition, 1949, Volume: 37, Issue:4

    Topics: Exercise; Glucose; Humans; Pyruvic Acid; Thiamine; Thiamine Deficiency; Thiazoles

1949
Thiamine deficiency, pyruvate metabolism and acid secretion in mouse stomachs in vitro.
    Gastroenterology, 1949, Volume: 13, Issue:13

    Topics: Biological Transport; Digestion; In Vitro Techniques; Pyruvic Acid; Stomach; Thiamine; Thiamine Defi

1949
[Peculiarities of carbohydrate metabolism in the rat liver due to the limited accessibility of thiamine].
    Biokhimiia (Moscow, Russia), 1983, Volume: 48, Issue:11

    Topics: Adenine Nucleotides; Animals; Carbohydrate Metabolism; Cyclic AMP; L-Lactate Dehydrogenase; Lactates

1983
Trypanosoma lewisi: pyruvate and transketolase activity in normal and thiamine deficient rats.
    The International journal of biochemistry, 1984, Volume: 16, Issue:6

    Topics: Animals; Body Weight; Erythrocytes; Female; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Ref

1984
The usefulness of the measurement of red blood cell enzyme activation in the detection of vitamin B1, B2 and B6 deficiency.
    International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement, 1983, Volume: 24

    Topics: Aged; Alcoholism; Aspartate Aminotransferases; Clinical Enzyme Tests; Erythrocytes; Glutathione Redu

1983
Lactate and pyruvate production in isolated thiamine-deficient rat diaphragm strips.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:3

    Topics: Animals; Diaphragm; Fatigue; Glucose; Glycolysis; Hydrogen; Hypoxia; In Vitro Techniques; Lactates;

1984
Elevation of blood keto acids in cerebrocortical necrosis.
    The Veterinary record, 1981, Jul-25, Volume: 109, Issue:4

    Topics: Animals; Cattle; Cattle Diseases; Cerebral Cortex; Glyoxylates; Keto Acids; Ketoglutaric Acids; Necr

1981
Brain pyruvate oxidation in experimental thiamin-deficiency encephalopathy.
    Clinica chimica acta; international journal of clinical chemistry, 1996, Nov-15, Volume: 255, Issue:1

    Topics: Alcohol Amnestic Disorder; Animals; Brain; Brain Chemistry; Female; Hypothalamus; Ketoglutarate Dehy

1996
Effects of thiamine deficiency on the secretion of insulin and the metabolism of glucose in isolated rat pancreatic islets.
    Biochemistry international, 1991, Volume: 25, Issue:3

    Topics: Animals; Carbon Dioxide; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerh

1991
Effect of a deficiency of thiamine on brain pyruvate dehydrogenase: enzyme assay by three different methods.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Animals; Brain; Carbon Dioxide; Coloring Agents; Enzyme Activation; Kinetics; Male; Mitochondria; NA

1988