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pyruvic acid and Supranuclear Palsy, Progressive

pyruvic acid has been researched along with Supranuclear Palsy, Progressive in 1 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Research Excerpts

ExcerptRelevanceReference
"Six patients with progressive supranuclear palsy (PSP) and 12 age-matched disease-free subjects participated in this study designed to compare rates of ATP production by intact mitochondria from biopsied skeletal muscle."1.29Muscle mitochondrial ATP production in progressive supranuclear palsy. ( Di Monte, DA; Harati, Y; Jankovic, J; Jewell, SA; Langston, JW; Sandy, MS, 1994)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Monte, DA1
Harati, Y1
Jankovic, J1
Sandy, MS1
Jewell, SA1
Langston, JW1

Other Studies

1 other study available for pyruvic acid and Supranuclear Palsy, Progressive

ArticleYear
Muscle mitochondrial ATP production in progressive supranuclear palsy.
    Journal of neurochemistry, 1994, Volume: 62, Issue:4

    Topics: Adenosine Triphosphate; Aged; Ascorbic Acid; Humans; Kinetics; Malates; Mitochondria; Muscles; Oxida

1994