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pyruvic acid and Starvation

pyruvic acid has been researched along with Starvation in 36 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Starvation: Lengthy and continuous deprivation of food. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Pyruvate kinase activity and the rates of gluconeogenesis and glycolysis in rat hepatocytes were evaluated by production of glucose and lactate + pyruvate from dihydroxyacetone during a feeding cycle or progressive starvation."7.67Development of gluconeogenesis from dihydroxyacetone in rat hepatocytes during a feeding cycle and starvation. ( Azzout, B; Peret, J, 1984)
"Pyruvate kinase activity and the rates of gluconeogenesis and glycolysis in rat hepatocytes were evaluated by production of glucose and lactate + pyruvate from dihydroxyacetone during a feeding cycle or progressive starvation."3.67Development of gluconeogenesis from dihydroxyacetone in rat hepatocytes during a feeding cycle and starvation. ( Azzout, B; Peret, J, 1984)
" Thereafter, a 24- or 48-hour starvation period caused a significant decrease of skeletal muscle and liver glycogen content in K+-depleted (KD) rats, whereas kidney glycogen concentration increased and heart glycogen remained unchanged."3.67Carbohydrate metabolism in potassium-depleted rats. ( Heidland, A; Hörl, WH; Schaefer, RM, 1985)
"Barth syndrome is a rare X-linked disease in which mild hypocholesterolemia is observed in some patients."1.36Reduction in cholesterol synthesis in response to serum starvation in lymphoblasts of a patient with Barth syndrome. ( Hatch, GM; Hauff, KD, 2010)
"Propionic acid did not inhibit [1-14C]palmitic acid oxidation by hepatocytes isolated from 48 h-starved rats."1.27Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes. ( Brass, EP; Fennessey, PV; Miller, LV, 1986)
"Induction of streptozotocin diabetes resulted in loss of pyruvate inhibition of the kinase in heart mitochondria at 48 h but not at 24 h whereas a significant increase of kinase activity was seen at 24 h."1.27Pyruvate inhibition of pyruvate dehydrogenase kinase is a physiological variable. ( Coore, HG; Lyn, D, 1985)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199025 (69.44)18.7374
1990's8 (22.22)18.2507
2000's2 (5.56)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hauff, KD1
Hatch, GM1
GARLAND, PB2
NEWSHOLME, EA2
RANDLE, PJ3
Jeoung, NH1
Wu, P1
Joshi, MA1
Jaskiewicz, J1
Bock, CB1
Depaoli-Roach, AA1
Harris, RA2
Palmer, TN2
Caldecourt, MA1
Warner, JP1
Sugden, MC5
Müller, MJ1
Seitz, HJ1
Fuller, SJ1
Gibbons, GF1
Pullinger, CR1
Björnsson, OG1
Wagenmakers, AJ1
Schepens, JT1
Veerkamp, JH1
Pösö, AR1
Mortimore, GE1
Watts, DI1
West, PS1
Azzout, B1
Peret, J1
Carrascosa, JM1
Martinez, P1
de Castro, IN1
Braggins, TJ1
Crow, KE1
McCormack, JG1
Edgell, NJ1
Denton, RM1
Maughan, RJ1
Large, V2
Soloviev, M1
Brunengraber, H1
Beylot, M2
Moir, AM1
Zammit, VA1
Owen, MR1
Halestrap, AP1
Priestman, DA1
Orfali, KA1
Carter, TC1
Ramdath, DD1
Coore, HG2
Kraus, A1
Holness, MJ2
Liu, YL1
González-Manchón, C1
Ayuso, MS2
Parrilla, R2
Roca, P1
Gianotti, M1
Palou, A1
Steele, RD1
Pérez-Sala, D1
Johnston, JD1
Brand, MD1
Rigoulet, M1
Leverve, XM1
Plomp, PJ1
Meijer, AJ1
Kinugasa, A1
Thurman, RG1
Brass, EP1
Fennessey, PV1
Miller, LV1
Lomax, MA1
Donaldson, IA1
Pogson, CI1
Lyn, D1
Schaefer, RM1
Heidland, A1
Hörl, WH1
Battersby, CM1
Alberti, KG1
Agius, L1

Other Studies

36 other studies available for pyruvic acid and Starvation

ArticleYear
Reduction in cholesterol synthesis in response to serum starvation in lymphoblasts of a patient with Barth syndrome.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2010, Volume: 88, Issue:4

    Topics: Acetic Acid; Acyltransferases; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters

2010
Effect of fatty acids, ketone bodies, diabetes and starvation on pyruvate metabolism in rat heart and diaphragm muscle.
    Nature, 1962, Jul-28, Volume: 195

    Topics: Animals; Diabetes Mellitus, Experimental; Diaphragm; Fatty Acids; Ketone Bodies; Myocardium; Pyruvat

1962
CITRATE AS AN INTERMEDIARY IN THE INHIBITION OF PHOSPHOFRUCTOKINASE IN RAT HEART MUSCLE BY FATTY ACIDS, KETONE BODIES, PYRUVATE, DIABETES, AND STARVATION.
    Nature, 1963, Oct-12, Volume: 200

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Citrates; Citric Acid; Diabetes Mellitus; Fatty Acids;

1963
Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.
    The Biochemical journal, 2006, Aug-01, Volume: 397, Issue:3

    Topics: Animals; Diaphragm; Fatty Acids; Glucose; Glycolysis; Homeostasis; Insulin; Isoenzymes; Lactic Acid;

2006
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.
    The Biochemical journal, 1984, Dec-15, Volume: 224, Issue:3

    Topics: Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lactates; Lactic Acid;

1984
Starvation-induced changes of hepatic glucose metabolism in hypo- and hyperthyroid rats in vivo.
    The Journal of nutrition, 1981, Volume: 111, Issue:8

    Topics: Animals; Citrates; Citric Acid; Cyclic AMP; Energy Metabolism; Gluconeogenesis; Hyperthyroidism; Hyp

1981
Reversible phosphorylation of pyruvate dehydrogenase in rat skeletal-muscle mitochondria. Effects of starvation and diabetes.
    The Biochemical journal, 1984, Apr-15, Volume: 219, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Diabetes Mellitus, Experimental; Dichloroacetic Acid; Enzy

1984
Changes in the sensitivity of lipogenesis in rat hepatocytes to hormones and precursors over the diurnal cycle and during longer-term starvation of donor animals.
    Journal of lipid research, 1984, Dec-01, Volume: 25, Issue:12

    Topics: Animals; Circadian Rhythm; Fatty Acids; Glucagon; Hormones; Insulin; Kinetics; Lipids; Liver; Male;

1984
Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation.
    The Biochemical journal, 1984, Dec-01, Volume: 224, Issue:2

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Diaphragm; Fatty Acids; Glucose; In Vitr

1984
Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14

    Topics: Alanine; Amino Acids; Animals; Caprylates; Lactates; Lactic Acid; Liver; Male; Proteins; Pyruvates;

1984
Proline and hepatic lipogenesis.
    Biochimica et biophysica acta, 1984, Apr-24, Volume: 798, Issue:3

    Topics: Animals; Citrates; Fatty Acids; Female; Lactates; Lactic Acid; Lipids; Liver; Picolinic Acids; Proli

1984
Development of gluconeogenesis from dihydroxyacetone in rat hepatocytes during a feeding cycle and starvation.
    The Biochemical journal, 1984, Mar-15, Volume: 218, Issue:3

    Topics: Animals; Dihydroxyacetone; Food; Gluconeogenesis; Glucose; Glycolysis; In Vitro Techniques; Lactates

1984
Ammonium ions enhance the flow through the pyruvate dehydrogenase in Ehrlich ascites tumor cells.
    Biochimie, 1982, Volume: 64, Issue:10

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Dioxide; Carcino

1982
The effects of high ethanol doses on rates of ethanol oxidation in rats. A reassessment of factors controlling rates of ethanol oxidation in vivo.
    European journal of biochemistry, 1981, Volume: 119, Issue:3

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Dose-Response Relationship, Drug; Ethanol; Lactates;

1981
Studies on the interactions of Ca2+ and pyruvate in the regulation of rat heart pyruvate dehydrogenase activity. Effects of starvation and diabetes.
    The Biochemical journal, 1982, Feb-15, Volume: 202, Issue:2

    Topics: Adenosine Diphosphate; Animals; Calcium; Diabetes Mellitus, Experimental; Epinephrine; Heart; In Vit

1982
A simple, rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20-mul blood sample.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Jul-01, Volume: 122, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Blood Glucose; Fluorometry; Humans; Hydroxybutyrates;

1982
Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats.
    The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 1

    Topics: Animals; Blood; Eating; Lactates; Lactic Acid; Male; Microdialysis; Osmolar Concentration; Pyruvates

1995
Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume.
    The Biochemical journal, 1995, Feb-01, Volume: 305 ( Pt 3)

    Topics: Animals; Carnitine O-Palmitoyltransferase; Cholesterol Esters; Diabetes Mellitus, Experimental; Este

1995
The mechanisms by which mild respiratory chain inhibitors inhibit hepatic gluconeogenesis.
    Biochimica et biophysica acta, 1993, Apr-05, Volume: 1142, Issue:1-2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Diuron; Glucagon; Gluconeog

1993
Pyruvate inhibition of pyruvate dehydrogenase kinase. Effects of progressive starvation and hyperthyroidism in vivo, and of dibutyryl cyclic AMP and fatty acids in cultured cardiac myocytes.
    FEBS letters, 1996, Sep-16, Volume: 393, Issue:2-3

    Topics: Animals; Bucladesine; Caprylates; Cells, Cultured; Female; Hyperthyroidism; Kinetics; Mitochondria,

1996
Suppression of beta-oxidation restores pyruvate inhibition of pyruvate dehydrogenase kinase in starved rat heart.
    Molecular and cellular biochemistry, 1996, Sep-20, Volume: 162, Issue:2

    Topics: Animals; Isoenzymes; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Protein Kinase Inhibitors

1996
Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin.
    Diabetes, 1999, Volume: 48, Issue:6

    Topics: Animals; Citric Acid Cycle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glutamic Acid

1999
Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression.
    The Biochemical journal, 2000, Mar-15, Volume: 346 Pt 3

    Topics: Animals; Female; Food; Isoenzymes; Mitochondria, Muscle; Muscle Fibers, Fast-Twitch; Muscle Fibers,

2000
Glucose utilization by skeletal muscles in vivo in experimental hyperthyroidism in the rat.
    The Biochemical journal, 1990, Oct-15, Volume: 271, Issue:2

    Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Food; Glucose; Glycogen; Hyperthyroidism

1990
On the mechanism of sodium 2-5-4 chlorophenylpentyloxirane-2-carboxylate (POCA) inhibition of hepatic gluconeogenesis.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Fatty Acids; Gluconeogenesis; Glucose; L

1990
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxy

1989
Blood-brain barrier transport of the alpha-keto acid analogs of amino acids.
    Federation proceedings, 1986, Volume: 45, Issue:7

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Binding, Competitive; Biological Transport; Blood-Brain

1986
Key role of L-alanine in the control of hepatic protein synthesis.
    The Biochemical journal, 1987, Jan-15, Volume: 241, Issue:2

    Topics: Alanine; Amino Acids; Animals; Glucose; Liver; Male; Peptide Chain Elongation, Translational; Polyri

1987
Stimulation of the respiration rate of rat liver mitochondria by sub-micromolar concentrations of extramitochondrial Ca2+.
    The Biochemical journal, 1987, Jul-01, Volume: 245, Issue:1

    Topics: Animals; Calcium; Female; Isocitrates; Ketoglutaric Acids; Mitochondria, Liver; Oxygen Consumption;

1987
Stimulation by glucose of gluconeogenesis in hepatocytes isolated from starved rats.
    The Biochemical journal, 1987, Aug-01, Volume: 245, Issue:3

    Topics: Animals; Glucagon; Gluconeogenesis; Glucose; Glycerol; In Vitro Techniques; Lactates; Lactic Acid; L

1987
Differential effect of glucagon on gluconeogenesis in periportal and pericentral regions of the liver lobule.
    The Biochemical journal, 1986, Jun-01, Volume: 236, Issue:2

    Topics: Animals; Female; Glucagon; Gluconeogenesis; Lactates; Lactic Acid; Liver; Oxygen Consumption; Perfus

1986
Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes.
    The Biochemical journal, 1986, May-15, Volume: 236, Issue:1

    Topics: Animals; Carnitine; Drug Interactions; In Vitro Techniques; Liver; Male; Mass Spectrometry; Oxidatio

1986
The effect of fatty acids and starvation on the metabolism of gluconeogenic precursors by isolated sheep liver cells.
    The Biochemical journal, 1986, Nov-15, Volume: 240, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cell Separation; Fatty Acids; Gluconeogenesis; Hydrox

1986
Pyruvate inhibition of pyruvate dehydrogenase kinase is a physiological variable.
    Biochemical and biophysical research communications, 1985, Feb-15, Volume: 126, Issue:3

    Topics: Adipose Tissue; Animals; Brain; Diabetes Mellitus, Experimental; Insulin; Kidney; Male; Mitochondria

1985
Carbohydrate metabolism in potassium-depleted rats.
    Nephron, 1985, Volume: 41, Issue:1

    Topics: Acetoacetates; Animals; Blood Glucose; Carbohydrate Metabolism; Female; Glucose; Glycogen; Insulin;

1985
Conversion of pyruvate into ketone bodies in rat hepatocyte suspensions.
    The Biochemical journal, 1985, Nov-01, Volume: 231, Issue:3

    Topics: Animals; In Vitro Techniques; Ketone Bodies; Liver; Male; Oxidation-Reduction; Palmitic Acid; Palmit

1985