pyruvic acid has been researched along with Shock in 14 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| " Hyperlactatemia with L/P ratio elevation and lactic acidosis is likely to be associated with inadequate tissue perfusion." | 3.70 | Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions. ( Kari, A; Ruokonen, E; Suistomaa, M; Takala, J, 2000) |
| "Hypoxic lactic acidosis was efficiently reversed in group PR, instead of group CR, (pH 7." | 1.48 | Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats. ( Li, ZY; Liu, R; Wang, SM; Yu, W; Zhang, HP; Zhou, FQ, 2018) |
| "Lactic acidosis was fully corrected and survival increased in group PR (50." | 1.43 | Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs. ( Bai, XD; Guo, SJ; Hu, S; Hu, XH; Li, ZY; Liu, R; Wang, SM; Zhou, FQ, 2016) |
| "The results suggest that hypovolemic shock perturbs glucose metabolism at the level of pyruvate utilization, resulting in deranged cerebral energy stores." | 1.42 | The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock. ( Awasthi, V; Hedrick, AF; Hussain, A; Rao, G; Xie, J; Yadav, VR, 2015) |
| "During hypovolemic shock, the lactate production increased and the glucose concentration decreased or remained normal." | 1.34 | Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock. ( Alhava, E; Härmä, M; Joukainen, S; Setälä, L; Uusaro, A, 2007) |
| "Heatstroke was induced by exposing the anesthetized rats to a high ambient temperature (Ta = 43 degrees C) until the moment at which MAP decreased from its peak level." | 1.33 | Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion. ( Ke, DS; Lin, MT; Wang, JL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, R | 2 |
| Wang, SM | 2 |
| Li, ZY | 2 |
| Yu, W | 1 |
| Zhang, HP | 1 |
| Zhou, FQ | 2 |
| Rao, G | 1 |
| Hedrick, AF | 1 |
| Yadav, VR | 1 |
| Xie, J | 1 |
| Hussain, A | 1 |
| Awasthi, V | 1 |
| Hu, XH | 1 |
| Guo, SJ | 1 |
| Bai, XD | 1 |
| Hu, S | 1 |
| Knobloch, K | 1 |
| Gohritz, A | 1 |
| Vogt, P | 1 |
| Samuelsson, A | 1 |
| Farnebo, S | 1 |
| Magnusson, B | 1 |
| Anderson, C | 1 |
| Tesselaar, E | 1 |
| Zettersten, E | 1 |
| Sjöberg, F | 1 |
| Chou, YT | 1 |
| Lai, ST | 1 |
| Lee, CC | 1 |
| Lin, MT | 3 |
| NEMETH, S | 1 |
| VIGAS, M | 1 |
| BLAIR, E | 1 |
| COWLEY, RA | 1 |
| TAIT, MK | 1 |
| Tenhunen, J | 1 |
| Wang, JL | 1 |
| Ke, DS | 1 |
| Chang, CP | 1 |
| Chen, SH | 1 |
| Setälä, L | 1 |
| Joukainen, S | 1 |
| Uusaro, A | 1 |
| Alhava, E | 1 |
| Härmä, M | 1 |
| BAIN, JA | 1 |
| POLLOCK, GH | 1 |
| STEIN, SN | 1 |
| Suistomaa, M | 1 |
| Ruokonen, E | 1 |
| Kari, A | 1 |
| Takala, J | 1 |
14 other studies available for pyruvic acid and Shock
| Article | Year |
|---|---|
Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats.
Topics: Acidosis, Lactic; Administration, Oral; Animals; Bicarbonates; Burns; Citric Acid; Disease Models, A | 2018 |
The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock.
Topics: Adenosine Triphosphate; Animals; Blood Substitutes; Brain; Citrate (si)-Synthase; Disease Models, An | 2015 |
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; F | 2016 |
Ultrasonic cardiac output monitoring and microcirculation: is it worthwhile to consider in reconstructive microsurgery?
Topics: Animals; Cardiac Output; Female; Glucose; Graft Occlusion, Vascular; Humans; Lactic Acid; Microcircu | 2009 |
Implications for burn shock resuscitation of a new in vivo human vascular microdosing technique (microdialysis) for dermal administration of noradrenaline.
Topics: Administration, Cutaneous; Adult; Burns; Dermis; Dose-Response Relationship, Drug; Female; Glucose; | 2012 |
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus | 2003 |
CHANGES IN THE LEVELS OF GLUCOSE, PYRUVATE AND PHOSPHATE IN THE BLOOD OF RABBITS UNDER THE INFLUENCE OF VARIOUS DOSES OF ENDOTOXIN.
Topics: Animals; Blood; Blood Glucose; Endotoxins; Glucose; Lagomorpha; Pharmacology; Phosphates; Pyruvates; | 1964 |
REFRACTORY SEPTIC SHOCK IN MAN. ROLE OF LACTATE AND PYRUVATE METABOLISM AND ACID-BASE BALANCE IN PROGNOSIS.
Topics: Acid-Base Equilibrium; Acidosis; Humans; Lactates; Lactic Acid; Male; Metabolism; Prognosis; Pyruvat | 1965 |
Can we distinguish between different types of local perfusion/metabolic derangement by regional venous concentrations of intermediary energy substrates?
Topics: Animals; Endotoxins; Glucose; Glycerol; Lactic Acid; Microdialysis; Perfusion; Pyruvic Acid; Reperfu | 2004 |
Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Catechols; Cerebrovascular Circulation; Glut | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock.
Topics: Animals; Female; Glucose; Graft Occlusion, Vascular; Lactic Acid; Microdialysis; Models, Biological; | 2007 |
Lactate, pyruvate, and acid-soluble phosphates in monkey brains treated with carbon dioxide and electric shock.
Topics: Animals; Brain; Brain Chemistry; Carbon Dioxide; Convulsive Therapy; Haplorhini; Humans; Lactates; L | 1949 |
Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions.
Topics: Acidosis, Lactic; APACHE; Biomarkers; Critical Care; Emergencies; Female; Finland; Glasgow Coma Scal | 2000 |