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pyruvic acid and Shock

pyruvic acid has been researched along with Shock in 14 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."7.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."3.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
" Hyperlactatemia with L/P ratio elevation and lactic acidosis is likely to be associated with inadequate tissue perfusion."3.70Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions. ( Kari, A; Ruokonen, E; Suistomaa, M; Takala, J, 2000)
"Hypoxic lactic acidosis was efficiently reversed in group PR, instead of group CR, (pH 7."1.48Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats. ( Li, ZY; Liu, R; Wang, SM; Yu, W; Zhang, HP; Zhou, FQ, 2018)
"Lactic acidosis was fully corrected and survival increased in group PR (50."1.43Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs. ( Bai, XD; Guo, SJ; Hu, S; Hu, XH; Li, ZY; Liu, R; Wang, SM; Zhou, FQ, 2016)
"The results suggest that hypovolemic shock perturbs glucose metabolism at the level of pyruvate utilization, resulting in deranged cerebral energy stores."1.42The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock. ( Awasthi, V; Hedrick, AF; Hussain, A; Rao, G; Xie, J; Yadav, VR, 2015)
"During hypovolemic shock, the lactate production increased and the glucose concentration decreased or remained normal."1.34Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock. ( Alhava, E; Härmä, M; Joukainen, S; Setälä, L; Uusaro, A, 2007)
"Heatstroke was induced by exposing the anesthetized rats to a high ambient temperature (Ta = 43 degrees C) until the moment at which MAP decreased from its peak level."1.33Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion. ( Ke, DS; Lin, MT; Wang, JL, 2005)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's7 (50.00)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, R2
Wang, SM2
Li, ZY2
Yu, W1
Zhang, HP1
Zhou, FQ2
Rao, G1
Hedrick, AF1
Yadav, VR1
Xie, J1
Hussain, A1
Awasthi, V1
Hu, XH1
Guo, SJ1
Bai, XD1
Hu, S1
Knobloch, K1
Gohritz, A1
Vogt, P1
Samuelsson, A1
Farnebo, S1
Magnusson, B1
Anderson, C1
Tesselaar, E1
Zettersten, E1
Sjöberg, F1
Chou, YT1
Lai, ST1
Lee, CC1
Lin, MT3
NEMETH, S1
VIGAS, M1
BLAIR, E1
COWLEY, RA1
TAIT, MK1
Tenhunen, J1
Wang, JL1
Ke, DS1
Chang, CP1
Chen, SH1
Setälä, L1
Joukainen, S1
Uusaro, A1
Alhava, E1
Härmä, M1
BAIN, JA1
POLLOCK, GH1
STEIN, SN1
Suistomaa, M1
Ruokonen, E1
Kari, A1
Takala, J1

Other Studies

14 other studies available for pyruvic acid and Shock

ArticleYear
Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats.
    The Journal of surgical research, 2018, Volume: 226

    Topics: Acidosis, Lactic; Administration, Oral; Animals; Bicarbonates; Burns; Citric Acid; Disease Models, A

2018
The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:9

    Topics: Adenosine Triphosphate; Animals; Blood Substitutes; Brain; Citrate (si)-Synthase; Disease Models, An

2015
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:4

    Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; F

2016
Ultrasonic cardiac output monitoring and microcirculation: is it worthwhile to consider in reconstructive microsurgery?
    Journal of reconstructive microsurgery, 2009, Volume: 25, Issue:2

    Topics: Animals; Cardiac Output; Female; Glucose; Graft Occlusion, Vascular; Humans; Lactic Acid; Microcircu

2009
Implications for burn shock resuscitation of a new in vivo human vascular microdosing technique (microdialysis) for dermal administration of noradrenaline.
    Burns : journal of the International Society for Burn Injuries, 2012, Volume: 38, Issue:7

    Topics: Administration, Cutaneous; Adult; Burns; Dermis; Dose-Response Relationship, Drug; Female; Glucose;

2012
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus

2003
CHANGES IN THE LEVELS OF GLUCOSE, PYRUVATE AND PHOSPHATE IN THE BLOOD OF RABBITS UNDER THE INFLUENCE OF VARIOUS DOSES OF ENDOTOXIN.
    Physiologia bohemoslovenica, 1964, Volume: 13

    Topics: Animals; Blood; Blood Glucose; Endotoxins; Glucose; Lagomorpha; Pharmacology; Phosphates; Pyruvates;

1964
REFRACTORY SEPTIC SHOCK IN MAN. ROLE OF LACTATE AND PYRUVATE METABOLISM AND ACID-BASE BALANCE IN PROGNOSIS.
    The American surgeon, 1965, Volume: 31

    Topics: Acid-Base Equilibrium; Acidosis; Humans; Lactates; Lactic Acid; Male; Metabolism; Prognosis; Pyruvat

1965
Can we distinguish between different types of local perfusion/metabolic derangement by regional venous concentrations of intermediary energy substrates?
    Shock (Augusta, Ga.), 2004, Volume: 22, Issue:2

    Topics: Animals; Endotoxins; Glucose; Glycerol; Lactic Acid; Microdialysis; Perfusion; Pyruvic Acid; Reperfu

2004
Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Catechols; Cerebrovascular Circulation; Glut

2005
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:4

    Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid;

2005
Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock.
    Journal of reconstructive microsurgery, 2007, Volume: 23, Issue:8

    Topics: Animals; Female; Glucose; Graft Occlusion, Vascular; Lactic Acid; Microdialysis; Models, Biological;

2007
Lactate, pyruvate, and acid-soluble phosphates in monkey brains treated with carbon dioxide and electric shock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1949, Volume: 71, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Carbon Dioxide; Convulsive Therapy; Haplorhini; Humans; Lactates; L

1949
Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:1

    Topics: Acidosis, Lactic; APACHE; Biomarkers; Critical Care; Emergencies; Female; Finland; Glasgow Coma Scal

2000