pyruvic acid has been researched along with Shock, Cardiogenic in 10 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Shock, Cardiogenic: Shock resulting from diminution of cardiac output in heart disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty consecutive adult patients who developed septic shock and lactic acidosis requiring the administration of vasopressors." | 3.70 | Evolution of lactate/pyruvate and arterial ketone body ratios in the early course of catecholamine-treated septic shock. ( Bollaert, PE; Gelot, AM; Larcan, A; Levy, B; Nabet, P; Sadoune, LO, 2000) |
| "Only 65% of patients with septic shock had hyperlactataemia at the onset of shock and 76% of these also had a high lactate/pyruvate ratio." | 1.38 | Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock. ( Bruzzi de Carvahlo, F; Cotton, F; De Backer, D; Orellano-Jimenez, C; Rimachi, R; Vincent, JL, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levitt, DG | 1 |
| Levitt, JE | 1 |
| Levitt, MD | 1 |
| Malik, M | 1 |
| Chaudhary, R | 1 |
| Pundir, CS | 1 |
| Levy, B | 2 |
| Perez, P | 1 |
| Perny, J | 1 |
| Thivilier, C | 1 |
| Gerard, A | 1 |
| Schillinger, W | 1 |
| Hünlich, M | 1 |
| Sossalla, S | 1 |
| Hermann, HP | 1 |
| Hasenfuss, G | 1 |
| Rimachi, R | 1 |
| Bruzzi de Carvahlo, F | 1 |
| Orellano-Jimenez, C | 1 |
| Cotton, F | 1 |
| Vincent, JL | 1 |
| De Backer, D | 1 |
| Nemoto, M | 3 |
| Sezai, A | 2 |
| Shiono, M | 2 |
| Orime, Y | 2 |
| Nakata, K | 2 |
| Hata, M | 2 |
| Yamada, H | 1 |
| Iida, M | 2 |
| Kashiwazaki, S | 2 |
| Kinishita, J | 1 |
| Koujima, T | 2 |
| Sezai, Y | 2 |
| Saitoh, T | 1 |
| Kinoshita, J | 1 |
| Furuichi, M | 1 |
| Eda, K | 1 |
| Hirose, H | 1 |
| Yoshino, T | 1 |
| Saitoh, A | 1 |
| Taniguchi, Y | 1 |
| Sadoune, LO | 1 |
| Gelot, AM | 1 |
| Bollaert, PE | 1 |
| Nabet, P | 1 |
| Larcan, A | 1 |
| Corbucci, GG | 1 |
| Gasparetto, A | 1 |
| Candiani, A | 1 |
| Crimi, G | 1 |
| Antonelli, M | 1 |
| Bufi, M | 1 |
| De Blasi, RA | 1 |
| Cooper, MB | 1 |
| Gohil, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Influence of High Vitamin C Dose on Lactate During Extracorporeal Circulation for Heart Surgery and During the 24 Hours Thereafter. (Double Blind Prospective Randomised Study)"[NCT04046861] | 200 participants (Anticipated) | Interventional | 2023-02-01 | Not yet recruiting | |||
| Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation[NCT00604331] | Phase 2 | 8 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Shock, Cardiogenic
| Article | Year |
|---|---|
Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source.
Topics: Animals; Critical Illness; Disease Models, Animal; Dogs; Humans; Hypoxia; Lactic Acid; Liver; Models | 2020 |
1 trial available for pyruvic acid and Shock, Cardiogenic
| Article | Year |
|---|---|
Comparison of norepinephrine-dobutamine to epinephrine for hemodynamics, lactate metabolism, and organ function variables in cardiogenic shock. A prospective, randomized pilot study.
Topics: Acidosis, Lactic; Aged; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dobutamine; Epinephrine; | 2011 |
8 other studies available for pyruvic acid and Shock, Cardiogenic
| Article | Year |
|---|---|
An improved enzyme nanoparticles based amperometric pyruvate biosensor for detection of pyruvate in serum.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Biosensing Techniques; Case-Control Studies; Enzymes, Im | 2019 |
Intracoronary pyruvate in cardiogenic shock as an adjunctive therapy to catecholamines and intra-aortic balloon pump shows beneficial effects on hemodynamics.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Cardiotonic Ag | 2011 |
Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock.
Topics: Aerobiosis; Aged; APACHE; Biomarkers; Female; Humans; Hypoxia; Lactic Acid; Male; Middle Aged; Pyruv | 2012 |
Experimental evaluation of the influence of complete artificial circulation on renal circulation and tissue metabolism -comparative study of pulsatile vs nonpulsatile circulation.
Topics: Analysis of Variance; Animals; beta 2-Microglobulin; Blood Urea Nitrogen; Creatinine; Disease Models | 2003 |
Renal circulation and cellular metabolism during left ventricular assisted circulation: comparison study of pulsatile and nonpulsatile assists.
Topics: Animals; beta 2-Microglobulin; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Anim | 1997 |
Major organ function under mechanical support: comparative studies of pulsatile and nonpulsatile circulation.
Topics: Animals; Blood Circulation; Cerebrovascular Circulation; Heart-Assist Devices; Hemodynamics; Ketone | 1999 |
Evolution of lactate/pyruvate and arterial ketone body ratios in the early course of catecholamine-treated septic shock.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Case-Control Studies; Catecholamines; Female; Hemo | 2000 |
Shock-induced damage to mitochondrial function and some cellular antioxidant mechanisms in humans.
Topics: Biopsy, Needle; Electron Transport Complex IV; Free Radicals; Glutathione; Hemodynamics; Humans; Mit | 1985 |