Page last updated: 2024-10-20

pyruvic acid and Reperfusion Injury

pyruvic acid has been researched along with Reperfusion Injury in 51 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of preventive enteral administration of ornithine alpha-ketoglutarate (OKG) in an ischemia-reperfusion rat model."7.77Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. ( Garcia, JH; Gonçalves, ES; Guimarães, SB; Prado Neto, AX; Rabelo, CM; Vasconcelos, PR, 2011)
"The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins."5.31Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002)
"Phosphoenolpyruvate (PEP) is a high-energy metabolite in the final step of glycolysis."5.30Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats. ( Chijiiwa, K; Hamasaki, N; Saiki, S; Shimizu, S; Tanaka, M; Yamaguchi, K, 1997)
" Therefore, we investigated whether glycine, sodium pyruvate, and resveratrol can either support or potentially harm regeneration when applied therapeutically after reperfusion injury."3.85Effect of Glycine, Pyruvate, and Resveratrol on the Regeneration Process of Postischemic Intestinal Mucosa. ( Brencher, L; Hamburger, T; Kirsch, M; Petrat, F; Stych, K, 2017)
"To investigate the effects of preventive enteral administration of ornithine alpha-ketoglutarate (OKG) in an ischemia-reperfusion rat model."3.77Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. ( Garcia, JH; Gonçalves, ES; Guimarães, SB; Prado Neto, AX; Rabelo, CM; Vasconcelos, PR, 2011)
"Acute kidney injury is a major clinical challenge affecting as many as 1 percent of all hospitalized patients."1.56Metabolic reprogramming associated with progression of renal ischemia reperfusion injury assessed with hyperpolarized [1- ( Bertelsen, LB; Laustsen, C; Nielsen, PM; Qi, H, 2020)
"In this study, we used a global cerebral ischemia induced by four-vessel occlusion as an established animal model for ischemic stroke to investigate metabolic changes after 24 h reperfusion, when transitions occur due to the onset of delayed neuronal death."1.48NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. ( Baranovicova, E; Cierny, D; Grendar, M; Kalenska, D; Lehotsky, J; Tomascova, A, 2018)
"Histological features of ischaemia and reperfusion injury were assessed."1.40Comparison of energy metabolism in liver grafts from donors after circulatory death and donors after brain death during cold storage and reperfusion. ( Ahmed, N; Mirza, DF; Murphy, N; Neil, DA; Perera, MT; Richards, DA; Silva, MA, 2014)
"Rat models of hemorrhagic shock were built up."1.34[Protective effect of sodium pyruvate on ischemia/reperfusion injury of rats subjected to hemorrhagic shock]. ( Guan, LD; Wang, B; Wang, GY; Wang, ZL; Wei, GZ; Zhao, L; Zhou, H, 2007)
"Transorbital 2 hour middle cerebral artery occlusion (MCAO) was performed in eight monkeys, which were studied with continuous microdialysis for 24 hours."1.31Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model. ( Enblad, P; Frykholm, P; Hillered, L; Långström, B; Persson, L; Valtysson, J; Watanabe, Y, 2001)
"The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins."1.31Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002)
"Phosphoenolpyruvate (PEP) is a high-energy metabolite in the final step of glycolysis."1.30Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats. ( Chijiiwa, K; Hamasaki, N; Saiki, S; Shimizu, S; Tanaka, M; Yamaguchi, K, 1997)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (17.65)18.2507
2000's17 (33.33)29.6817
2010's22 (43.14)24.3611
2020's3 (5.88)2.80

Authors

AuthorsStudies
Zhang, JJ3
Shen, HQ1
Deng, JT1
Jiang, LL2
Zhang, QY1
Xiong, Y1
Zhang, ZZ3
Wang, YL3
Nielsen, PM2
Qi, H2
Bertelsen, LB2
Laustsen, C2
Osada, Y1
Nakagawa, S1
Ishibe, K1
Takao, S1
Shimazaki, A1
Itohara, K1
Imai, S1
Yonezawa, A1
Nakagawa, T1
Matsubara, K1
Scott, GF1
Nguyen, AQ1
Cherry, BH1
Hollrah, RA1
Salinas, I1
Williams, AG2
Ryou, MG3
Mallet, RT5
Gregorini, M1
Corradetti, V1
Pattonieri, EF1
Rocca, C1
Milanesi, S1
Peloso, A1
Canevari, S1
De Cecco, L1
Dugo, M1
Avanzini, MA1
Mantelli, M1
Maestri, M1
Esposito, P1
Bruno, S1
Libetta, C1
Dal Canton, A1
Rampino, T1
Khalilov, RA1
Dzhafarova, AM1
Khizrieva, SI1
Brencher, L1
Petrat, F2
Stych, K1
Hamburger, T1
Kirsch, M1
Baranovicova, E1
Grendar, M1
Kalenska, D1
Tomascova, A1
Cierny, D1
Lehotsky, J1
Chen, L1
Luo, Z1
Fu, W1
Liao, X1
Cui, Z1
Zhou, J1
Zager, RA1
Johnson, AC1
Becker, K1
Gurji, HA1
White, DW1
Hoxha, B2
Sun, J4
Harbor, JP1
Schulz, DR1
Olivencia-Yurvati, AH3
Perera, MT1
Richards, DA1
Silva, MA1
Ahmed, N1
Neil, DA1
Murphy, N1
Mirza, DF1
Ke, JJ1
He, XH2
Zhan, J1
Chen, DL2
Wang, YP1
Huang, CY2
Kuo, WT1
Lee, TC1
Chen, CT1
Peng, WH1
Lu, KS1
Yang, CY1
Yu, LC1
Mikkelsen, E1
Kristensen, ML1
Nørregaard, R1
Stødkilde-Jørgensen, H1
Li, T1
Zhang, Z1
Kolwicz, SC1
Abell, L1
Roe, ND1
Kim, M1
Zhou, B1
Cao, Y1
Ritterhoff, J1
Gu, H1
Raftery, D1
Sun, H1
Tian, R1
Olson, AK1
Hyyti, OM1
Cohen, GA1
Ning, XH1
Sadilek, M1
Isern, N1
Portman, MA1
Kim, K1
Jo, YH1
Rhee, JE1
Kim, TY1
Lee, JH2
Kwon, WY1
Suh, GJ1
Lee, CC1
Singer, AJ1
Zubkov, VI1
Khytryĭ, HP1
Luk'ianchuk, VD1
Shalamaĭ, AS1
Rönn, T1
de Groot, H1
Kannerup, AS1
Grønbæk, H1
Funch-Jensen, P1
Karlsen, S1
Mortensen, FV1
Guan, LD1
Wang, ZL1
Zhao, L1
Wang, B1
Wang, GY1
Wei, GZ1
Zhou, H1
Flaherty, DC1
Gurji, H1
Simecka, JW1
Nakajima, J1
Bessho, M1
Adachi, T1
Yamagishi, T1
Tokuno, S1
Horinouchi, H1
Ohsuzu, F1
Gonçalves, ES1
Rabelo, CM1
Prado Neto, AX1
Garcia, JH1
Guimarães, SB1
Vasconcelos, PR1
Liu, R1
Ren, M1
Yang, SH1
Zhang, J1
Deng, Z1
Liao, J1
Song, C1
Liang, C1
Xue, H1
Wang, L1
Zhang, K1
Yan, G1
Kavianipour, M1
Ehlers, MR1
Malmberg, K1
Ronquist, G2
Ryden, L1
Wikström, G2
Gutniak, M1
Yoo, MH1
Lee, JY1
Lee, SE1
Koh, JY1
Yoon, YH1
Bäckström, T1
Liska, J1
Oldner, A1
Lockowandt, U1
Franco-Cereceda, A1
Olek, RA1
Antosiewicz, J1
Popinigis, J1
Gabbianelli, R1
Fedeli, D1
Falcioni, G1
Knott, EM1
Lei, Y1
Carles, M1
Dellamonica, J1
Roux, J1
Lena, D1
Levraut, J1
Pittet, JF1
Boileau, P1
Raucoules-Aime, M1
de Groot, MJ1
Coumans, WA1
Willemsen, PH1
van der Vusse, GJ1
Cicalese, L2
Lee, K1
Schraut, W1
Watkins, S1
Borle, A1
Stanko, R1
Nakatani, T1
Sakamoto, Y1
Ando, H1
Kobayashi, K1
Grynberg, A1
Demaison, L2
Saiki, S1
Yamaguchi, K1
Chijiiwa, K1
Shimizu, S1
Hamasaki, N1
Tanaka, M1
Fukuse, T1
Hirata, T1
Nakamura, T1
Kawashima, M1
Hitomi, S1
Wada, H1
Anderson, MF1
Sims, NR1
Pechan, I1
Holoman, M1
Zahorec, R1
Rendekova, V1
Kalnovicova, T1
Hola, J1
Halcak, L1
Chen, CJ1
Cheng, FC2
Liao, SL1
Chen, WY1
Lin, NN1
Kuo, JS1
Zemgulis, V1
Bjerner, T1
Henze, A1
Waldenström, A1
Thelin, S1
Enblad, P2
Frykholm, P2
Valtysson, J2
Silander, HC1
Andersson, J1
Fasth, KJ1
Watanabe, Y2
Långström, B2
Hillered, L2
Persson, L2
Sileri, P1
Schena, S1
Morini, S1
Rastellini, C1
Pham, S1
Benedetti, E1
Badr, AE1
Yin, W1
Mychaskiw, G1
Zhang, JH1
Moreau, D1
Vergely-Vandriesse, C1
Grégoire, S1
Degois, M1
Rochette, L1
Lin, JY1
Chung, SY1
Lin, MC1
Vlessis, AA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103]30 participants (Actual)Interventional2018-02-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pyruvic acid and Reperfusion Injury

ArticleYear
Fatty acid oxidation in the heart.
    Journal of cardiovascular pharmacology, 1996, Volume: 28 Suppl 1

    Topics: Adenosine Triphosphate; Animals; Calcium; Fatty Acids; Fish Oils; Humans; Lactic Acid; Mitochondria,

1996

Trials

1 trial available for pyruvic acid and Reperfusion Injury

ArticleYear
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia-reperfusion.
    British journal of anaesthesia, 2008, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Glucose;

2008

Other Studies

49 other studies available for pyruvic acid and Reperfusion Injury

ArticleYear
Effect of peritoneal dialysis solution with different pyruvate concentrations on intestinal injury.
    Experimental biology and medicine (Maywood, N.J.), 2020, Volume: 245, Issue:7

    Topics: Animals; Claudin-1; Dialysis Solutions; Hemodynamics; Intercellular Adhesion Molecule-1; Interleukin

2020
Metabolic reprogramming associated with progression of renal ischemia reperfusion injury assessed with hyperpolarized [1-
    Scientific reports, 2020, 06-02, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Disease Models, Animal; Disease Progression; K

2020
Antibiotic-induced microbiome depletion alters renal glucose metabolism and exacerbates renal injury after ischemia-reperfusion injury in mice.
    American journal of physiology. Renal physiology, 2021, 10-01, Volume: 321, Issue:4

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Glucose; Gastrointestinal Microbiome; Gen

2021
Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest.
    Experimental biology and medicine (Maywood, N.J.), 2017, Volume: 242, Issue:10

    Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Glutathione Reductase; Glyceraldehyde-3-Pho

2017
Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:12

    Topics: Adenosine; Allopurinol; Animals; Biomarkers; Energy Metabolism; Extracellular Vesicles; Gene Express

2017
Effect of Hypothermia on Kinetic Characteristics of Lactate Dehydrogenase in Rat Brain under Conditions of Global Ischemia and Reperfusion.
    Bulletin of experimental biology and medicine, 2017, Volume: 163, Issue:3

    Topics: Animals; Animals, Outbred Strains; Biocatalysis; Blood Flow Velocity; Brain; Brain Chemistry; Brain

2017
Effect of Glycine, Pyruvate, and Resveratrol on the Regeneration Process of Postischemic Intestinal Mucosa.
    BioMed research international, 2017, Volume: 2017

    Topics: Animals; beta-Fructofuranosidase; Cell Proliferation; Disease Models, Animal; Glycine; Injections, I

2017
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:3

    Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine

2018
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
    Disease markers, 2013, Volume: 35, Issue:5

    Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophos

2013
Renal cortical pyruvate depletion during AKI.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:5

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; Glycogen; Hydrogen P

2014
Pyruvate-enriched resuscitation: metabolic support of post-ischemic hindlimb muscle in hypovolemic goats.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:2

    Topics: Animals; Antioxidants; Citric Acid; Dinoprost; Goats; Hypovolemia; Infusions, Intravenous; Lactic Ac

2014
Comparison of energy metabolism in liver grafts from donors after circulatory death and donors after brain death during cold storage and reperfusion.
    The British journal of surgery, 2014, Volume: 101, Issue:7

    Topics: Adult; Aged; Brain Death; Cryopreservation; Energy Metabolism; Glycerol; Graft Survival; Heart Arres

2014
Protection against intestinal injury from hemorrhagic shock by direct peritoneal resuscitation with pyruvate in rats.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:5

    Topics: Animals; Dialysis Solutions; Drug Evaluation, Preclinical; Fluid Therapy; Inflammation Mediators; In

2014
EFFECT OF INTRAPERITONEAL RESUSCITATION WITH DIFFERENT CONCENTRATIONS OF SODIUM PYRUVATE ON INTESTINAL ISCHEMIA REPERFUSION INJURY IN HEMORRHAGIC SHOCK RAT.
    Shock (Augusta, Ga.), 2016, Volume: 45, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Infusions, Parenteral; Intestines; Male; Pyruvic Acid; Ra

2016
Distinct cytoprotective roles of pyruvate and ATP by glucose metabolism on epithelial necroptosis and crypt proliferation in ischaemic gut.
    The Journal of physiology, 2017, 01-15, Volume: 595, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Enterocytes; Glucose; Jejunum; Liver; Male; Microscopy,

2017
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
    American journal of physiology. Renal physiology, 2017, 03-01, Volume: 312, Issue:3

    Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An

2017
Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury.
    Cell metabolism, 2017, 02-07, Volume: 25, Issue:2

    Topics: Acetylglucosamine; Amino Acids, Branched-Chain; Animals; Glucose; Glycosylation; Heart Function Test

2017
Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:6

    Topics: Animals; Animals, Newborn; Carbon Isotopes; Cardiopulmonary Bypass; Chromatography, Liquid; Citric A

2008
Effect of speed of rewarming and administration of anti-inflammatory or anti-oxidant agents on acute lung injury in an intestinal ischemia model treated with therapeutic hypothermia.
    Resuscitation, 2010, Volume: 81, Issue:1

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Dexamethasone; Disease Models, Animal; Hypothermia, Indu

2010
[Ishemic-reperfusion syndrome prophylaxis in general hypothermia in experiment].
    Klinichna khirurhiia, 2009, Issue:5

    Topics: Animals; Antioxidants; Body Temperature; Catalase; Female; Glucose; Glutathione; Homeostasis; Hypoth

2009
Protection by pyruvate infusion in a rat model of severe intestinal ischemia-reperfusion injury.
    The Journal of surgical research, 2011, May-15, Volume: 167, Issue:2

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Infusions, In

2011
Partial liver ischemia is followed by metabolic changes in the normally perfused part of the liver during reperfusion.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2010, Volume: 45, Issue:2

    Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Glucose; Glycerol; Humans; Ischemia;

2010
[Protective effect of sodium pyruvate on ischemia/reperfusion injury of rats subjected to hemorrhagic shock].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2007, Volume: 23, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Disease Models, Animal; Kidney; L-Lactate Dehydrogenase; Liver

2007
Pyruvate-enriched resuscitation protects hindlimb muscle from ischemia-reperfusion injury.
    Military medicine, 2010, Volume: 175, Issue:12

    Topics: Animals; Fluid Therapy; Goats; Hindlimb; Isotonic Solutions; Male; Muscle, Skeletal; Pyruvic Acid; R

2010
Hemoglobin vesicle improves recovery of cardiac function after ischemia-reperfusion by attenuating oxidative stress in isolated rat hearts.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:5

    Topics: Animals; Blood Substitutes; Catalase; Coronary Circulation; Glutathione; Glutathione Disulfide; Glut

2011
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats.
    Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1

    Topics: Animals; Calcium Carbonate; Disease Models, Animal; Intestinal Diseases; Intestine, Small; Ischemia;

2011
Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway.
    Stroke, 2012, Volume: 43, Issue:4

    Topics: Animals; Brain; Cell Line, Tumor; Disease Models, Animal; Erythropoietin; Gene Expression Regulation

2012
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:4

    Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate D

2013
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium.
    Peptides, 2003, Volume: 24, Issue:4

    Topics: Animals; Area Under Curve; Blood Glucose; Cardiovascular System; Glucagon; Glucagon-Like Peptide 1;

2003
Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure-induced ischemia in vivo.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cell Culture Techniques; Cell Survival; Chlorides; Cytoprotection;

2004
Splanchnic metabolism during gut ischemia and short-term endotoxin and hemorrhagic shock as evaluated by intravasal microdialysis.
    Shock (Augusta, Ga.), 2004, Volume: 21, Issue:6

    Topics: Abdomen; Animals; Endotoxemia; Endotoxins; Glucose; Glycerol; Hemodynamics; Ileum; Ischemia; Lactic

2004
Pyruvate but not lactate prevents NADH-induced myoglobin oxidation.
    Free radical biology & medicine, 2005, Jun-01, Volume: 38, Issue:11

    Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Free Radicals; Horses; Hydrogen P

2005
Pyruvate mitigates oxidative stress during reperfusion of cardioplegia-arrested myocardium.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:3

    Topics: Animals; Heart; Heart Arrest, Induced; Models, Animal; Myocardium; Oxidative Stress; Pyruvic Acid; R

2006
Substrate-induced changes in the lipid content of ischemic and reperfused myocardium. Its relation to hemodynamic recovery.
    Circulation research, 1993, Volume: 72, Issue:1

    Topics: Animals; Disease Models, Animal; Fatty Acids; Glucose; Glycerol; Heart; Lactates; Lactic Acid; Male;

1993
Pyruvate prevents ischemia-reperfusion mucosal injury of rat small intestine.
    American journal of surgery, 1996, Volume: 171, Issue:1

    Topics: Animals; Intestinal Diseases; Intestinal Mucosa; Luminescent Measurements; Male; Neutrophils; Pyruva

1996
Effects of platelet-activating factor antagonist E5880 on intrahepatic and systemic metabolic responses to transient hepatic inflow occlusion and reperfusion in the rabbit.
    World journal of surgery, 1996, Volume: 20, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Adenine Nucleotides; Ammonia; Analysis of Variance; Animals; Blood Gas

1996
Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats.
    The Journal of surgical research, 1997, Volume: 73, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteries; Energy Metabolism; Infusions, In

1997
Influence of deflated and anaerobic conditions during cold storage on rat lungs.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2

    Topics: Air; Anaerobiosis; Animals; Bronchoalveolar Lavage Fluid; Cryopreservation; Lactic Acid; Lung; Male;

1999
Mitochondrial respiratory function and cell death in focal cerebral ischemia.
    Journal of neurochemistry, 1999, Volume: 73, Issue:3

    Topics: Animals; Arterial Occlusive Diseases; Cell Death; Cerebral Arterial Diseases; Cerebral Infarction; I

1999
[Parameters of energy metabolism in patients after vascular reconstructive surgical procedures].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:8

    Topics: Acid-Base Equilibrium; Adult; Antioxidants; Energy Metabolism; Female; Humans; Ischemia; Lactic Acid

1999
Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion.
    Neuroscience letters, 2000, Jun-23, Volume: 287, Issue:2

    Topics: Animals; Antioxidants; Brain; Catalase; Energy Metabolism; Free Radicals; Glutathione Peroxidase; Is

2000
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
    Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2

    Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal

2001
Middle cerebral artery occlusion and reperfusion in primates monitored by microdialysis and sequential positron emission tomography.
    Stroke, 2001, Volume: 32, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Hypoxanthine; Infarction

2001
Pyruvate inhibits hepatic ischemia-reperfusion injury in rats.
    Transplantation, 2001, Jul-15, Volume: 72, Issue:1

    Topics: Animals; Apoptosis; Ischemia; Liver; Liver Circulation; Male; Pyruvic Acid; Rats; Rats, Inbred ACI;

2001
Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model.
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 71, Issue:4

    Topics: Animals; Brain Damage, Chronic; Extracellular Space; Glutamic Acid; Glycerol; Infarction, Middle Cer

2001
Effect of hyperbaric oxygen on striatal metabolites: a microdialysis study in awake freely moving rats after MCA occlusion.
    Brain research, 2001, Oct-19, Volume: 916, Issue:1-2

    Topics: Animals; Brain Ischemia; Corpus Striatum; Energy Metabolism; Extracellular Space; Glucose; Glutamic

2001
Effects of dietary polyunsaturated fatty acids and hepatic steatosis on the functioning of isolated working rat heart under normoxic conditions and during post-ischemic reperfusion.
    Molecular and cellular biochemistry, 2001, Volume: 224, Issue:1-2

    Topics: Adenine; Animals; Aorta; Ascorbic Acid; Body Weight; Cardiac Output; Cell Respiration; Cholesterol,

2001
Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique.
    Life sciences, 2002, Jul-05, Volume: 71, Issue:7

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Energy Metabolism; Gerbillinae; Gluco

2002
NADH-linked substrate dependence of peroxide-induced respiratory inhibition and calcium efflux in isolated renal mitochondria.
    The Journal of biological chemistry, 1990, Jan-25, Volume: 265, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Calcium; Glutamates; Hydroxybutyrates; In Vitro Techniques; Kidney;

1990