pyruvic acid has been researched along with Pregnancy in 149 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
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" In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by phenylalanine administration to female Wistar rats during pregnancy and lactation on some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 7.80 | Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring. ( Bortoluzzi, VT; de Franceschi, ID; Rieger, E; Wannmacher, CM, 2014) |
" In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by leucine administration to female Wistar rats during pregnancy and lactation on some oxidative stress parameters as well as the activities of some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 7.79 | Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring. ( Campos, AG; de Franceschi, ID; Feksa, LR; Rech, VC; Rieger, E; Rojas, DB; Vargas, AP; Wannmacher, CM, 2013) |
" In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by phenylalanine administration to female Wistar rats during pregnancy and lactation on some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 3.80 | Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring. ( Bortoluzzi, VT; de Franceschi, ID; Rieger, E; Wannmacher, CM, 2014) |
" In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by leucine administration to female Wistar rats during pregnancy and lactation on some oxidative stress parameters as well as the activities of some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 3.79 | Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring. ( Campos, AG; de Franceschi, ID; Feksa, LR; Rech, VC; Rieger, E; Rojas, DB; Vargas, AP; Wannmacher, CM, 2013) |
"Fetuses with intrauterine growth restriction (FGR) have impaired oxidative and energy metabolism, with persistent consequences on their postnatal development." | 1.91 | Decreased Pyruvate but Not Fatty Acid Driven Mitochondrial Respiration in Skeletal Muscle of Growth Restricted Fetal Sheep. ( Anderson, MJ; Bidwell, CA; Kelly, AC; Limesand, SW; Luna-Ramirez, RI; Zhao, W, 2023) |
"Gestational hypoxemia is often associated with reduced birth weight, yet how hypoxemia controls uteroplacental nutrient metabolism and supply to the fetus is unclear." | 1.62 | Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia. ( Brown, LD; Jones, AK; Julian, CG; Limesand, SW; Lorca, RA; Moore, LG; Rozance, PJ; Wesolowski, SR, 2021) |
"Normal pregnancy is characterized by reduced pyruvate kinase expression within lymphocytes and neutrophils." | 1.36 | Leukocyte pyruvate kinase expression is reduced in normal human pregnancy but not in pre-eclampsia. ( Elfline, M; Hassan, S; Madsen-Bouterse, SA; Mittal, P; Petty, HR; Romero, R; Xu, Y; Zhu, A, 2010) |
"Pregnancy is an important physiological condition associated with hemodynamic and endocrine changes that affect the heart." | 1.33 | Structural, functional and metabolic remodeling of rat left ventricular myocytes in normal and in sodium-supplemented pregnancy. ( Bassien-Capsa, V; Chorvatova, A; Comte, B; Fouron, JC, 2006) |
"Amniocytes with an established cytochrome c oxidase deficiency were also investigated." | 1.28 | Prenatal diagnosis of systemic disorders of the respiratory chain in cultured amniocytes and chorionic villus fibroblasts by studying the formation of lactate and pyruvate from glucose. ( Bakkeren, JA; Feller, N; Ruitenbeek, W; Ruiter, J; Sengers, RC; Trijbels, JM; Wanders, RJ; Wijburg, FA, 1992) |
"Ischemia was produced by inflating the aortic balloon thereby reducing the uterine blood flow." | 1.27 | Effect of ischemia on fatty acid metabolism in fetal lung. ( Ayromlooi, J; Das, DK; Neogi, A, 1983) |
"Intrauterine growth retardation was induced in newborn dogs after 3 days of maternal nutritional deprivation (birth weight 251 +/- 7 versus 227 +/- 7 g, p less than 0." | 1.27 | Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs. ( Kliegman, RM, 1988) |
"We examined the possibility that in preeclampsia complicated by fetal growth retardation, placental energy state is low either because of impaired glycolysis or because of ischemia resulting from reduced maternal placental blood flow." | 1.27 | Placental glycolysis and energy metabolism in preeclampsia. ( Bloxam, DL; Bullen, BE; Lao, TT; Walters, BN, 1987) |
"After 15 min of hypoxemia we repeated the measurements." | 1.26 | Fetal myocardial oxygen and carbohydrate consumption during acutely induced hypoxemia. ( Fisher, DJ; Heymann, MA; Rudolph, AM, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 52 (34.90) | 18.7374 |
1990's | 31 (20.81) | 18.2507 |
2000's | 34 (22.82) | 29.6817 |
2010's | 22 (14.77) | 24.3611 |
2020's | 10 (6.71) | 2.80 |
Authors | Studies |
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Jones, AK | 1 |
Rozance, PJ | 1 |
Brown, LD | 1 |
Lorca, RA | 1 |
Julian, CG | 1 |
Moore, LG | 1 |
Limesand, SW | 2 |
Wesolowski, SR | 1 |
Li, P | 1 |
Zhang, H | 1 |
Yan, K | 1 |
Sui, L | 1 |
Du, Y | 1 |
Hu, J | 1 |
Xu, H | 1 |
Yang, X | 1 |
Liang, X | 1 |
Seo, H | 1 |
Kramer, AC | 1 |
McLendon, BA | 1 |
Cain, JW | 1 |
Burghardt, RC | 1 |
Wu, G | 1 |
Bazer, FW | 1 |
Johnson, GA | 1 |
Zhang, T | 1 |
Zheng, Y | 1 |
Han, R | 1 |
Kuang, T | 1 |
Min, C | 1 |
Wang, H | 1 |
Zhao, Y | 1 |
Wang, J | 1 |
Yang, L | 1 |
Che, D | 1 |
Pujol, C | 3 |
Lebigot, E | 3 |
Gaignard, P | 3 |
Galai, S | 3 |
Kraoua, I | 3 |
Bault, JP | 3 |
Dard, R | 3 |
Youssef-Turki, IB | 3 |
Omar, S | 3 |
Boutron, A | 4 |
Wai, T | 3 |
Slama, A | 4 |
Wenjing, J | 1 |
Huaying, J | 1 |
Lihua, Y | 1 |
Yuanhong, SA | 1 |
Jimei, X | 1 |
Hongqi, S | 1 |
Jingyan, S | 1 |
Zhengao, S | 1 |
Zhao, W | 1 |
Kelly, AC | 1 |
Luna-Ramirez, RI | 1 |
Bidwell, CA | 1 |
Anderson, MJ | 1 |
Yao, W | 1 |
Wang, T | 1 |
Xia, J | 1 |
Li, J | 2 |
Yu, X | 1 |
Huang, F | 1 |
Smith, LM | 1 |
Wade, TP | 2 |
Friesen-Waldner, LJ | 2 |
McKenzie, CA | 2 |
Harada, K | 1 |
Chihara, T | 1 |
Hayasaka, Y | 1 |
Mita, M | 1 |
Takizawa, M | 1 |
Ishida, K | 1 |
Arai, M | 1 |
Tsuno, S | 1 |
Matsumoto, M | 1 |
Ishihara, T | 1 |
Ueda, H | 1 |
Kitaguchi, T | 1 |
Tsuboi, T | 1 |
Liu, LX | 1 |
Rowe, GC | 1 |
Yang, S | 1 |
Damilano, F | 1 |
Chan, MC | 1 |
Lu, W | 1 |
Jang, C | 1 |
Wada, S | 1 |
Morley, M | 1 |
Hesse, M | 1 |
Fleischmann, BK | 1 |
Rabinowitz, JD | 1 |
Das, S | 1 |
Rosenzweig, A | 1 |
Arany, Z | 1 |
Bauersachs, S | 1 |
Simintiras, CA | 1 |
Sturmey, RG | 1 |
Krebs, S | 1 |
Bick, J | 1 |
Blum, H | 1 |
Wolf, E | 1 |
Lonergan, P | 1 |
Forde, N | 1 |
Markovic, S | 1 |
Fages, A | 1 |
Roussel, T | 1 |
Hadas, R | 1 |
Brandis, A | 1 |
Neeman, M | 1 |
Frydman, L | 1 |
Bortoluzzi, VT | 1 |
de Franceschi, ID | 2 |
Rieger, E | 2 |
Wannmacher, CM | 2 |
de Souza, DK | 1 |
Salles, LP | 1 |
Rosa e Silva, AA | 1 |
Detka, J | 1 |
Kurek, A | 1 |
Kucharczyk, M | 1 |
Głombik, K | 1 |
Basta-Kaim, A | 1 |
Kubera, M | 1 |
Lasoń, W | 1 |
Budziszewska, B | 1 |
Pinto, J | 1 |
Almeida, LM | 1 |
Martins, AS | 1 |
Duarte, D | 1 |
Domingues, MR | 1 |
Barros, AS | 1 |
Galhano, E | 1 |
Pita, C | 1 |
Almeida, Mdo C | 1 |
Carreira, IM | 1 |
Gil, AM | 1 |
Sinclair, KJ | 1 |
Michael, B | 1 |
Chen, AP | 1 |
de Vrijer, B | 1 |
Regnault, TR | 1 |
Orczyk-Pawilowicz, M | 1 |
Jawien, E | 1 |
Deja, S | 1 |
Hirnle, L | 1 |
Zabek, A | 1 |
Mlynarz, P | 1 |
Vanderperre, B | 1 |
Herzig, S | 1 |
Krznar, P | 1 |
Hörl, M | 1 |
Ammar, Z | 1 |
Montessuit, S | 1 |
Pierredon, S | 1 |
Zamboni, N | 1 |
Martinou, JC | 1 |
Bowman, CE | 1 |
Zhao, L | 1 |
Hartung, T | 1 |
Wolfgang, MJ | 1 |
Koch, F | 1 |
Lamp, O | 1 |
Eslamizad, M | 1 |
Weitzel, J | 1 |
Kuhla, B | 1 |
Virgiliou, C | 1 |
Gika, HG | 1 |
Witting, M | 1 |
Bletsou, AA | 1 |
Athanasiadis, A | 1 |
Zafrakas, M | 1 |
Thomaidis, NS | 1 |
Raikos, N | 1 |
Makrydimas, G | 1 |
Theodoridis, GA | 1 |
Balaban, B | 1 |
Urman, B | 1 |
Ata, B | 1 |
Isiklar, A | 1 |
Larman, MG | 1 |
Hamilton, R | 1 |
Gardner, DK | 8 |
LENZI, E | 1 |
Botros, L | 1 |
Sakkas, D | 1 |
Seli, E | 1 |
Mitchell, M | 1 |
Schulz, SL | 1 |
Armstrong, DT | 1 |
Lane, M | 6 |
Yan, EB | 1 |
Baburamani, AA | 1 |
Walker, AM | 1 |
Walker, DW | 1 |
Tsuzuki, Y | 1 |
Takeba, Y | 1 |
Kumai, T | 1 |
Matsumoto, N | 1 |
Mizuno, M | 1 |
Murano, K | 1 |
Asoh, K | 1 |
Takagi, M | 1 |
Yamamoto, H | 1 |
Kobayashi, S | 1 |
Cohn, BR | 1 |
Joe, BN | 1 |
Zhao, S | 1 |
Kornak, J | 1 |
Zhang, VY | 1 |
Iman, R | 1 |
Kurhanewicz, J | 1 |
Vahidi, K | 1 |
Yu, J | 1 |
Caughey, AB | 1 |
Swanson, MG | 1 |
Amer-Wåhlin, I | 1 |
Nord, A | 1 |
Bottalico, B | 1 |
Hansson, SR | 1 |
Ley, D | 1 |
Marsál, K | 1 |
Ungerstedt, U | 2 |
Nordström, CH | 1 |
Pelican, KM | 1 |
Spindler, RE | 2 |
Pukazhenthi, BS | 1 |
Wildt, DE | 1 |
Ottinger, MA | 1 |
Howard, J | 1 |
Xu, Y | 1 |
Madsen-Bouterse, SA | 1 |
Romero, R | 1 |
Hassan, S | 1 |
Mittal, P | 1 |
Elfline, M | 1 |
Zhu, A | 1 |
Petty, HR | 1 |
Zeiger, SL | 1 |
Stankowski, JN | 1 |
McLaughlin, B | 1 |
Krisher, RL | 3 |
Prather, RS | 1 |
Brekke, EM | 1 |
Walls, AB | 1 |
Schousboe, A | 1 |
Waagepetersen, HS | 1 |
Sonnewald, U | 1 |
Shimizu, I | 1 |
Ishikawa, E | 1 |
Fukuda, T | 1 |
Okazaki, S | 1 |
Li, Q | 1 |
Wang, G | 1 |
Zhang, J | 1 |
Zhou, P | 1 |
Wang, TY | 1 |
Cui, W | 1 |
Luo, MJ | 1 |
Tan, JH | 1 |
Vargas, AP | 1 |
Rojas, DB | 1 |
Campos, AG | 1 |
Rech, VC | 1 |
Feksa, LR | 1 |
Brivet, M | 1 |
Garcia-Cazorla, A | 1 |
Lyonnet, S | 1 |
Dumez, Y | 1 |
Nassogne, MC | 1 |
Touati, G | 1 |
Legrand, A | 1 |
Saudubray, JM | 1 |
Massieu, L | 1 |
Haces, ML | 1 |
Montiel, T | 1 |
Hernández-Fonseca, K | 1 |
Gopichandran, N | 1 |
Leese, HJ | 9 |
FRIEDBERG, V | 1 |
DIEMER, K | 1 |
GASTALDI, A | 2 |
HO, P | 2 |
REBER, EF | 2 |
KYANK, H | 1 |
GALLETTI, F | 1 |
WIDHOLM, O | 1 |
JARVINEN, PA | 1 |
NOVARA, A | 1 |
CARESANO, G | 1 |
TOSCHI, P | 1 |
HODR, J | 2 |
HERZMANN, J | 1 |
JANDA, J | 1 |
GOETZE, T | 1 |
GOETZE, E | 1 |
TOIVANEN, P | 1 |
DAHL, M | 1 |
TOIVANEN, A | 1 |
FABIANO, A | 1 |
OTEY, E | 1 |
STENGER, V | 1 |
EITZMAN, D | 1 |
ANDERSEN, T | 1 |
GESSNER, I | 1 |
PRYSTOWSKY, H | 2 |
MARX, GF | 2 |
GREENE, NM | 2 |
HUCKABEE, WE | 1 |
METCALFE, J | 1 |
BARRON, DH | 1 |
MARKEES, S | 1 |
KASER, O | 1 |
LANZ, R | 1 |
Kedryna, T | 1 |
Gumińska, M | 1 |
Lucyna, Z | 1 |
Yao, XH | 1 |
Chen, L | 1 |
Nyomba, BL | 1 |
Bassien-Capsa, V | 1 |
Fouron, JC | 1 |
Comte, B | 1 |
Chorvatova, A | 1 |
Dumollard, R | 1 |
Ward, Z | 1 |
Carroll, J | 1 |
Duchen, MR | 1 |
Arai, T | 1 |
Kusaba, A | 1 |
Takeguchi, A | 1 |
Tanaka, Y | 2 |
Ozawa, T | 1 |
Yoshida, T | 1 |
Sako, T | 1 |
Hayashi, T | 1 |
Blair, H | 1 |
Oh, C | 1 |
Dong, Y | 1 |
Harman, C | 1 |
Mighty, HE | 1 |
Kopelman, J | 1 |
Thompson, LP | 1 |
Noordin, L | 1 |
San, GT | 1 |
Singh, HJ | 1 |
Othman, MS | 1 |
Hafizah, W | 1 |
Plucinski, TM | 1 |
Baldwin, RL | 1 |
Gilbert, M | 2 |
Hauguel, S | 1 |
Bouisset, M | 2 |
Nazyrov, AT | 1 |
Ramanathan, S | 1 |
Masih, AK | 1 |
Ashok, U | 1 |
Arismendy, J | 1 |
Turndorf, H | 1 |
Sodha, RJ | 1 |
Proegler, M | 1 |
Schneider, H | 1 |
Nieder, GL | 2 |
Corder, CN | 2 |
Tiałowska, B | 1 |
Klimek, J | 1 |
Zelewski, L | 3 |
Das, DK | 1 |
Ayromlooi, J | 1 |
Neogi, A | 1 |
Rushakoff, RJ | 1 |
Kalkhoff, RK | 1 |
Fisher, DJ | 2 |
Heymann, MA | 2 |
Rudolph, AM | 2 |
Swierczyński, J | 2 |
Scisłowski, P | 1 |
Aleksandrowicz, Z | 2 |
Turner, K | 1 |
Martin, KL | 3 |
Woodward, BJ | 1 |
Lenton, EA | 1 |
Kunievsky, B | 1 |
Pretsky, J | 1 |
Yavin, E | 1 |
Omar, HA | 1 |
Figueroa, R | 1 |
Tejani, N | 1 |
Wolin, MS | 1 |
Darcy-Vrillon, B | 1 |
Posho, L | 1 |
Morel, MT | 1 |
Bernard, F | 1 |
Blachier, F | 1 |
Meslin, JC | 1 |
Duée, PH | 1 |
Thompson, JG | 1 |
Bell, AC | 1 |
Pugh, PA | 1 |
Tervit, HR | 1 |
Batt, P | 1 |
Steingrímsdóttir, T | 1 |
Ronquist, G | 1 |
Ulmsten, U | 1 |
Dringen, R | 1 |
Wiesinger, H | 1 |
Hamprecht, B | 1 |
Brison, DR | 1 |
Hewitson, LC | 1 |
Eriksson, UJ | 1 |
Borg, LA | 1 |
Conaghan, J | 3 |
Hardy, K | 6 |
Handyside, AH | 3 |
Winston, RM | 4 |
Robinson, FM | 1 |
Paraschos, T | 1 |
Wicks, R | 1 |
Franks, S | 1 |
Renfree, MB | 1 |
Omu, AE | 1 |
Oforofuo, IA | 1 |
Engidawork, E | 1 |
Chen, Y | 1 |
Dell'Anna, E | 1 |
Goiny, M | 1 |
Lubec, G | 1 |
Andersson, K | 1 |
Herrera-Marschitz, M | 1 |
Devreker, F | 2 |
Nordström, L | 1 |
Chua, S | 1 |
Roy, A | 1 |
Naka, K | 1 |
Persson, B | 1 |
Arulkumaran, S | 1 |
Khurana, NK | 1 |
Niemann, H | 2 |
Van den Bergh, M | 1 |
Winston, J | 1 |
Biramane, J | 1 |
Englert, Y | 1 |
Wrenzycki, C | 1 |
De Sousa, P | 1 |
Overström, EW | 1 |
Duby, RT | 1 |
Herrmann, D | 1 |
Watson, AJ | 1 |
O'Callaghan, D | 1 |
Boland, MP | 1 |
Geshi, M | 1 |
Takenouchi, N | 1 |
Yamauchi, N | 1 |
Nagai, T | 1 |
Pool, TB | 1 |
Pantaleon, M | 1 |
Ryan, JP | 1 |
Gil, M | 1 |
Kaye, PL | 1 |
Swain, JE | 2 |
Bormann, CL | 2 |
Kalhan, SC | 1 |
Parimi, P | 1 |
Van Beek, R | 1 |
Gilfillan, C | 1 |
Saker, F | 1 |
Gruca, L | 1 |
Sauer, PJ | 1 |
Stevens, J | 1 |
Schoolcraft, WB | 1 |
McKenna, MC | 1 |
Hopkins, IB | 1 |
Carey, A | 1 |
Teng, C | 1 |
Battaglia, FC | 1 |
Meschia, G | 1 |
Narkewicz, MR | 1 |
Wilkening, RB | 1 |
Clark, SG | 1 |
Walters, EM | 1 |
Wheeler, MB | 1 |
Houghton, FD | 1 |
Barr, KJ | 1 |
Walter, G | 1 |
Gabriel, HD | 1 |
Grümmer, R | 1 |
Traub, O | 1 |
Winterhager, E | 1 |
Kidder, GM | 1 |
Frøen, JF | 1 |
Munkeby, BH | 1 |
Stray-Pedersen, B | 1 |
Saugstad, OD | 1 |
Anai, T | 1 |
Urata, K | 1 |
Miyakawa, I | 1 |
Van Cappellen Van Walsum, AM | 1 |
Jongsma, HW | 1 |
Wevers, RA | 1 |
Nijhuis, JG | 1 |
Crevels, J | 1 |
Engelke, UF | 1 |
De Abreu, RA | 1 |
Moolenaar, SH | 1 |
Oeseburg, B | 1 |
Nijland, R | 1 |
Wanders, RJ | 1 |
Wijburg, FA | 1 |
Ruiter, J | 1 |
Trijbels, JM | 1 |
Ruitenbeek, W | 1 |
Sengers, RC | 1 |
Bakkeren, JA | 1 |
Feller, N | 1 |
Ito, M | 1 |
Kobashi, H | 1 |
Naito, E | 1 |
Saijo, T | 1 |
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Tarín, JJ | 1 |
Flisińska-Bojanowska, A | 2 |
Gill, J | 2 |
Komosa, M | 2 |
Fraslon, C | 1 |
Rolland, G | 1 |
Bourbon, JR | 1 |
Rieutort, M | 1 |
Valenza, C | 1 |
Harding, JE | 1 |
Charlton, VE | 1 |
Haufe, CC | 1 |
Schulze, HP | 1 |
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Dargel, R | 1 |
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Nöschel, H | 1 |
Schröder, S | 1 |
Müller, B | 1 |
Gross, W | 1 |
Michels, W | 1 |
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Gianotti, M | 1 |
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Balkovetz, DF | 1 |
Leibach, FH | 1 |
Mahesh, VB | 1 |
Ganapathy, V | 1 |
Munday, MR | 1 |
Williamson, DH | 1 |
Floka, EI | 1 |
Kliegman, RM | 1 |
Kaneoka, T | 1 |
Taguchi, S | 1 |
Shimizu, H | 1 |
Shirakawa, K | 1 |
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Bloxam, DL | 1 |
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Polak, MJ | 1 |
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Cuezva, JM | 1 |
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Stähler, E | 1 |
Buchholz, R | 1 |
Zorzano, A | 1 |
Lasunción, MA | 1 |
Herrera, E | 1 |
Morton, KE | 1 |
Jackson, MC | 1 |
Gillmer, MD | 1 |
Brodziński, W | 1 |
Laudański, T | 1 |
Cano, A | 1 |
Martínez, P | 1 |
Parrilla, JJ | 1 |
Abad, L | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis[NCT00608010] | 186 participants (Actual) | Interventional | 2006-10-31 | Completed | |||
PGT for Aneuploidy Does Not Enhance Live Birth in Young Patients (≤35 Years): a Randomized Controlled Trial of Single Blastocyst Frozen Embryo Transfers (ClinicalTrials.Gov ID: NCT03095053)[NCT03095053] | 302 participants (Actual) | Interventional | 2017-03-23 | Completed | |||
Randomized Comparison to Freeze Human Embryos by Either Vitrification or Slow Freezing Protocols[NCT00910390] | 584 participants (Actual) | Interventional | 2009-04-30 | Completed | |||
The Clinical Outcome of Ultra-low Oxygen Tension on Post Thawed Human Blastocyst[NCT03817671] | 168 participants (Anticipated) | Interventional | 2018-11-20 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
A clinical pregnancy was defined as a cycle with a fetal sac observed on ultrasound after 5 weeks of gestation (NCT03095053)
Timeframe: >5 weeks of gestation
Intervention | Participants (Count of Participants) |
---|---|
Euploid Subgroup | 49 |
Morphology Group | 76 |
A live birth cycle was defined as a cycle with a delivery after 20 weeks of gestation. (NCT03095053)
Timeframe: >20 weeks gestation
Intervention | Participants (Count of Participants) |
---|---|
Euploid Subgroup | 45 |
Morphology Group | 65 |
A miscarriage was defined as the loss of a clinical pregnancy before 20 weeks of gestation. (NCT03095053)
Timeframe: <20 weeks
Intervention | Participants (Count of Participants) |
---|---|
Euploid Subgroup | 3 |
Morphology Group | 11 |
3 reviews available for pyruvic acid and Pregnancy
Article | Year |
---|---|
Aspects of energetic substrate metabolism of in vitro and in vivo bovine embryos.
Topics: Animals; Blastocyst; Carbon Dioxide; Cattle; Embryo Culture Techniques; Energy Metabolism; Female; F | 2015 |
Early human embryo metabolism.
Topics: Adenosine Triphosphate; Animals; Blastocyst; Cleavage Stage, Ovum; Embryology; Energy Metabolism; Fa | 1993 |
Embryo nutrition and energy metabolism and its relationship to embryo growth, differentiation, and viability.
Topics: Amino Acids; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Deve | 2000 |
6 trials available for pyruvic acid and Pregnancy
Article | Year |
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A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation.
Topics: Adult; Blastocyst; Cohort Studies; Cryopreservation; Embryo Culture Techniques; Embryo, Mammalian; E | 2008 |
Normal development and metabolic activity of preimplantation embryos in vitro from patients with polycystic ovaries.
Topics: Adult; Blastocyst; Cell Count; Cell Death; Cleavage Stage, Ovum; Culture Techniques; Embryo Transfer | 1995 |
Glutamine improves human preimplantation development in vitro.
Topics: Blastocyst; Cell Count; Cell Death; Culture Media; Culture Techniques; Embryonic Development; Female | 1998 |
Noninvasive assessment of glucose and pyruvate uptake by human embryos after intracytoplasmic sperm injection and during the formation of pronuclei.
Topics: Embryo Implantation; Embryo, Mammalian; Female; Glucose; Humans; Male; Pregnancy; Prospective Studie | 2000 |
Human embryo biopsy on the 2nd day after insemination for preimplantation diagnosis: removal of a quarter of embryo retards cleavage.
Topics: Biopsy; Blastocyst; Cell Count; Cleavage Stage, Ovum; Embryo, Mammalian; Embryonic Development; Fema | 1992 |
A comparison of the effects of four intravenous solutions for the treatment of ketonuria during labour.
Topics: Female; Glucose; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Ketone Bodies; Lactates; | 1985 |
140 other studies available for pyruvic acid and Pregnancy
Article | Year |
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Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia.
Topics: Adaptation, Physiological; Amino Acids; AMP-Activated Protein Kinase Kinases; Animals; Female; Glyco | 2021 |
Insufficient pyruvate in culture medium arrests mouse embryos at the first cleavage stage associated with abnormal epigenetic modifications.
Topics: Animals; Blastocyst; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Female; Mice; Preg | 2022 |
Elongating porcine conceptuses can utilize glutaminolysis as an anaplerotic pathway to maintain the TCA cycle†.
Topics: Animals; Carbon Isotopes; Female; Glucose; Glutamic Acid; Glutamine; Ketoglutaric Acids; Pregnancy; | 2022 |
Effects of pyruvate on early embryonic development and zygotic genome activation in pigs.
Topics: Animals; Embryonic Development; Female; Fertilization in Vitro; Gene Expression Regulation, Developm | 2022 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy.
Topics: Biological Transport; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Pregn | 2023 |
Xiaoyi Yusi decoction improves fertilization and embryo transfer outcomes in patients with endometriosis.
Topics: Citric Acid; Embryo Transfer; Endometriosis; Female; Fertilization; Humans; Male; Pregnancy; Pyruvic | 2023 |
Decreased Pyruvate but Not Fatty Acid Driven Mitochondrial Respiration in Skeletal Muscle of Growth Restricted Fetal Sheep.
Topics: Animals; Fatty Acids; Female; Fetal Growth Retardation; Fetus; Humans; Muscle, Skeletal; Palmitoylca | 2023 |
Dietary Garcinol Attenuates Hepatic Pyruvate and Triglyceride Accumulation by Inhibiting P300/CBP-Associated Factor in Mid-to-Late Pregnant Rats.
Topics: Acetylation; Animals; Antioxidants; Body Weight; Diet; Female; Glycolysis; Lactic Acid; Lipogenesis; | 2020 |
Optimizing SNR for multi-metabolite hyperpolarized carbon-13 MRI using a hybrid flip-angle scheme.
Topics: Algorithms; Animals; Carbon Isotopes; Female; Guinea Pigs; Liver; Magnetic Resonance Imaging; Pregna | 2020 |
Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.
Topics: Animals; Biosensing Techniques; Cells, Cultured; Female; Glycolysis; Green Fluorescent Proteins; HeL | 2020 |
PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.
Topics: Animals; Citric Acid Cycle; Fatty Acids; Female; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Myo | 2017 |
Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.
Topics: Animals; Blastocyst; Cattle; Embryonic Development; Endometrium; Female; Gene Expression Regulation, | 2017 |
Placental physiology monitored by hyperpolarized dynamic
Topics: Animals; Bicarbonates; Carbon Isotopes; Disease Models, Animal; Female; Humans; Lactic Acid; Magneti | 2018 |
Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring.
Topics: Animals; Cerebral Cortex; Creatine; Drug Therapy, Combination; Energy Metabolism; Female; Hippocampu | 2014 |
Brain glucose metabolism in an animal model of depression.
Topics: Administration, Oral; Animals; Brain; Depression; Disease Models, Animal; Female; Glucose; Glucoseph | 2015 |
Impact of fetal chromosomal disorders on maternal blood metabolome: toward new biomarkers?
Topics: Acetates; Adult; Biomarkers; Blood Glucose; Case-Control Studies; Chromosome Disorders; Citric Acid; | 2015 |
Hyperpolarized [1-(13) C]pyruvate MRI for noninvasive examination of placental metabolism and nutrient transport: A feasibility study in pregnant guinea pigs.
Topics: Animals; Feasibility Studies; Female; Fetus; Guinea Pigs; Imaging, Three-Dimensional; Lactic Acid; M | 2016 |
Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Amino Acids; Amniotic Fluid; Female; Fetal Development; | 2016 |
Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
Topics: Animals; Anion Transport Proteins; Citric Acid Cycle; Diet, Ketogenic; Female; Fibroblasts; Genes, L | 2016 |
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Topics: Alanine Transaminase; Animals; Brain; Embryo, Mammalian; Embryonic Development; Female; Genes, Letha | 2016 |
Metabolic Response to Heat Stress in Late-Pregnant and Early Lactation Dairy Cows: Implications to Liver-Muscle Crosstalk.
Topics: Animals; Cattle; Climate Change; Eating; Fatty Acids; Female; Forkhead Box Protein O3; Gluconeogenes | 2016 |
Amniotic Fluid and Maternal Serum Metabolic Signatures in the Second Trimester Associated with Preterm Delivery.
Topics: Adult; Amniocentesis; Amniotic Fluid; Biomarkers; Case-Control Studies; Female; Gestational Age; Glu | 2017 |
The urinary elimination of pyruvic acid in childbirth in relation to the load of vit. B1.
Topics: Female; Humans; Obstetric Labor Complications; Pregnancy; Pyruvic Acid; Urine; Vitamin B Deficiency; | 1948 |
Metabolomics and its application for non-invasive embryo assessment in IVF.
Topics: Amino Acids; Animals; Culture Media; Embryo Implantation; Embryo Transfer; Embryo, Mammalian; Female | 2008 |
Metabolic and mitochondrial dysfunction in early mouse embryos following maternal dietary protein intervention.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Signaling; Cleavage Stage, Ovum; Die | 2009 |
Changes in cerebral blood flow, cerebral metabolites, and breathing movements in the sheep fetus following asphyxia produced by occlusion of the umbilical cord.
Topics: Animals; Asphyxia; Biomarkers; Blood Flow Velocity; Blood Pressure; Brain; Carbon Dioxide; Cerebrova | 2009 |
Antenatal glucocorticoid therapy increase cardiac alpha-enolase levels in fetus and neonate rats.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cyclic AMP; Dexamethasone; Female; Fetus; Gestati | 2009 |
Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using (1)H HR-MAS spectroscopy.
Topics: Adult; Alanine; Amniotic Fluid; Betaine; Biomarkers; Citric Acid; Creatinine; Female; Glucose; Human | 2009 |
Fetal cerebral energy metabolism and electrocardiogram during experimental umbilical cord occlusion and resuscitation.
Topics: Animals; Brain; Brain Chemistry; Cardiopulmonary Resuscitation; Disease Models, Animal; Electrocardi | 2010 |
Progestin exposure before gonadotropin stimulation improves embryo development after in vitro fertilization in the domestic cat.
Topics: Animals; Cats; Female; Fertilization in Vitro; Glucose; Gonadotropins; Lactic Acid; Male; Oocytes; O | 2010 |
Leukocyte pyruvate kinase expression is reduced in normal human pregnancy but not in pre-eclampsia.
Topics: Adult; Calcium Signaling; Cross-Sectional Studies; Down-Regulation; Female; Flow Cytometry; Fluoroim | 2010 |
Assessing neuronal bioenergetic status.
Topics: Adenosine Triphosphate; Animals; Brain; Cell Extracts; Cell Hypoxia; Cell Line, Tumor; Cell Survival | 2011 |
A role for the Warburg effect in preimplantation embryo development: metabolic modification to support rapid cell proliferation.
Topics: Adenosine Triphosphate; Animals; Cell Proliferation; Citric Acid Cycle; Embryo Culture Techniques; E | 2012 |
Quantitative importance of the pentose phosphate pathway determined by incorporation of 13C from [2-13C]- and [3-13C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons.
Topics: Acetyl Coenzyme A; Amino Acids; Animals; Carbon Isotopes; Cells, Cultured; Citric Acid Cycle; Female | 2012 |
[Blood glucose, urinary glucose, blood ketone bodies, urine ketone bodies, blood lactic acid, and blood pyruvic acid].
Topics: Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glycosuria; Humans; Ketone Bodies; | 2012 |
Combined inhibitory effects of pyruvate and low temperature on postovulatory aging of mouse oocytes.
Topics: Animals; Blastocyst; Cell Culture Techniques; Cellular Senescence; Cold Temperature; Culture Media; | 2012 |
Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring.
Topics: Animals; Antioxidants; Cerebral Cortex; Creatine; Female; Hippocampus; Lactation; Leucine; Male; Map | 2013 |
Impaired mitochondrial pyruvate importation in a patient and a fetus at risk.
Topics: Algeria; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Consanguinity; Digitonin | 2003 |
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids; | 2003 |
Metabolic characterization of the bovine blastocyst, inner cell mass, trophectoderm and blastocoel fluid.
Topics: Amino Acids; Analysis of Variance; Animals; Blastocyst; Blastoderm; Cattle; Cell Count; Cells, Cultu | 2003 |
[Studies on pyruvic acid in pregnancy].
Topics: Blood; Female; Humans; Labor, Obstetric; Pregnancy; Pyruvates; Pyruvic Acid; Work | 1954 |
[Metabolism of carbohydrates in pregnancy; blood changes of pyruvic acid and alpha-ketoglutaric acid after glucose tolerance test].
Topics: Carbohydrate Metabolism; Carbohydrates; Glucose Tolerance Test; Humans; Keto Acids; Ketoglutaric Aci | 1955 |
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac | 1957 |
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac | 1957 |
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac | 1957 |
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac | 1957 |
[Enzymatic pyruvic acid determination in the blood in normal pregnancy and it toxicoses, before and after carbohydrate loading, and in umbilical cord blood].
Topics: Carbohydrates; Female; Fetal Blood; Hexoses; Humans; Pre-Eclampsia; Pregnancy; Pyruvates; Pyruvic Ac | 1957 |
[Research on blood pyruvic acid in kidney diseases].
Topics: Kidney Diseases; Pregnancy; Pyelonephritis; Pyruvic Acid; Vascular Diseases | 1958 |
[Pyruvic acid content of blood in toxemias & hyperemesis gravidarum & the effect of cocarboxylase].
Topics: Female; Humans; Hyperemesis Gravidarum; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pyruvic A | 1958 |
[Behavior of pyruvic acid in normal pregnant women after glucose administration].
Topics: Blood Glucose; Female; Glucose; Glucose Tolerance Test; Humans; Pregnancy; Pyruvates; Pyruvic Acid | 1958 |
[The cerebrospinal fluid in physiological pregnancy and in pregnancy toxemia: observations on the content and on the variations of pyruvic acid and transaminases].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Pyruvates; Pyruvic Acid; Transaminases | 1960 |
[Contribution to the study of fetal metabolism. alpha-Ketoglutaric acid and pyruvic acid in maternal and umbilical cord blood].
Topics: Female; Fetal Blood; Fetus; Humans; Kernicterus; Ketoglutaric Acids; Pregnancy; Pyruvates; Pyruvic A | 1960 |
[Relations between glucose and pyruvic acid in maternal and umbilical cord blood after administration of glucose and of Cori ester in fetal distress].
Topics: Blood Glucose; Esters; Female; Fetal Blood; Fetal Distress; Glucose; Humans; Phosphates; Pregnancy; | 1960 |
[Modification of the glycemia level, pyruvic acid level and the level of inorganic phosphorus by application of glucose during labor with consideration to hypoxia of the fetus].
Topics: Blood Glucose; Female; Fetus; Glucose; Humans; Hypoxia; Labor, Obstetric; Phosphorus; Pregnancy; Pyr | 1959 |
[Glutamic acid--pyruvic acid and glutamic acid-oxalacetic acid transaminase in maternal and embryonal organs, placenta, maternal serum and amniotic fluid of gravid rats in normal and pathological conditions].
Topics: Amniotic Fluid; Animals; Female; Fetus; Glutamic Acid; Oxaloacetic Acid; Placenta; Pregnancy; Pyruvi | 1961 |
Changes in the blood sugar and pyruvic acid blood level after the administration of glucose in protracted labour.
Topics: Blood Glucose; Dental Care; Female; Glucose; Humans; Labor, Obstetric; Pregnancy; Pyruvates; Pyruvic | 1961 |
URINARY EXCRETION OF PYRUVIC ACID AND LACTIC ACID IN PREMATURE AND FULL-TERM NEWBORN INFANTS.
Topics: Abruptio Placentae; Female; Humans; Infant, Newborn; Infant, Premature; Lactates; Lactic Acid; Pre-E | 1963 |
[INFLUENCE OF INSULIN ON HEMATIC VARIATIONS OF PYRUVIC ACID IN LABOR].
Topics: Blood; Carbohydrate Metabolism; Female; Humans; Insulin; Labor, Obstetric; Lipid Metabolism; Physiol | 1964 |
MOVEMENTS OF LACTATE AND PYRUVATE IN THE PREGNANT UTERUS OF THE HUMAN.
Topics: Biomedical Research; Blood; Female; Fetus; Humans; Lactates; Lactic Acid; Maternal-Fetal Exchange; P | 1964 |
MATERNAL LACTATE, PYRUVATE, AND EXCESS LACTATE PRODUCTION DURING LABOR AND DELIVERY.
Topics: Blood; Carbohydrate Metabolism; Delivery, Obstetric; Drug Therapy; Female; Humans; Labor, Obstetric; | 1964 |
LACTATE/PYRUVATE RATIO OF UMBILICAL VEIN BLOOD.
Topics: Anesthesia; Anesthesia, Obstetrical; Blood Chemical Analysis; Delivery, Obstetric; Female; Humans; H | 1965 |
Movements of lactate and pyruvate in pregnant uterus.
Topics: Female; Humans; Lactates; Lactic Acid; Movement; Pregnancy; Pyruvates; Pyruvic Acid; Uterus | 1962 |
[Pyruvic acid metabolism in normal and abnormal pregnancy, in the anesthetized state, and under roentgen irradiation].
Topics: Anesthesia; Anesthesiology; Female; Pregnancy; Pyruvic Acid; X-Rays | 1950 |
Pyruvate kinase activity in the placentas of women living in polluted and unpolluted environments.
Topics: Air Pollution; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Isoenzymes; Placenta; Pola | 2004 |
Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes.
Topics: Age Factors; Animals; Blood Glucose; Central Nervous System Depressants; Diabetes Mellitus, Type 2; | 2006 |
Structural, functional and metabolic remodeling of rat left ventricular myocytes in normal and in sodium-supplemented pregnancy.
Topics: Animals; Cell Count; Cell Size; Echocardiography; Female; Glucose; Heart Ventricles; Microscopy, Con | 2006 |
Regulation of redox metabolism in the mouse oocyte and embryo.
Topics: Animals; Cytosol; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Flavin-Adenine Di | 2007 |
Comparison of plasma metabolite concentrations and peripheral leukocyte enzyme activities in sheep fed on different diets in New Zealand and Japan.
Topics: Animal Feed; Animals; Blood Glucose; Blood Proteins; Cholesterol; Diet; Female; Insulin; Japan; L-La | 2007 |
Chronic hypoxia differentially increases glutathione content and gamma-glutamyl cysteine synthetase expression in fetal guinea pig organs.
Topics: Animals; Blotting, Western; Body Weight; Female; Fetal Hypoxia; Fetus; Glutamate-Cysteine Ligase; Gl | 2008 |
Pyruvate reduces in vitro the embryotoxic effect of peritoneal fluid from infertile women with endometriosis.
Topics: Animals; Ascitic Fluid; Culture Media; Embryo, Mammalian; Endometriosis; Female; Humans; In Vitro Te | 2008 |
Effects of hormones on mammary adenosine 3',5'-monophosphate levels and metabolism in normal and adrenalectomized lactating rats.
Topics: Adrenalectomy; Alprostadil; Animals; Cyclic AMP; Epinephrine; Female; Glucose; Hormones; Lactation; | 1982 |
Uterine blood flow and substrate uptake in conscious rabbit during late gestation.
Topics: Animals; Blood Glucose; Consciousness; Fatty Acids, Nonesterified; Female; Ketone Bodies; Lactates; | 1984 |
[Adaptive changes in carbohydrate metabolism in the placenta in experimental fetal anoxia].
Topics: Animals; Female; Fetal Hypoxia; Glucose; Lactates; Lactic Acid; Placenta; Pregnancy; Pyruvates; Pyru | 1984 |
Concentrations of lactate and pyruvate in maternal and neonatal blood with different intravenous fluids used for prehydration before epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Glucose; Cesarean Section; Female; Fetal | 1984 |
Transfer and metabolism of norepinephrine studied from maternal-to-fetal and fetal-to-maternal sides in the in vitro perfused human placental lobe.
Topics: Antipyrine; Clorgyline; Female; Glucose; Humans; In Vitro Techniques; Lactates; Lactic Acid; Mandeli | 1984 |
Pyruvate and lactate levels in oviducts of cycling, pregnant, and pseudopregnant mice.
Topics: Analysis of Variance; Animals; Estrus; Fallopian Tubes; Female; L-Lactate Dehydrogenase; Lactates; L | 1983 |
Progesterone biosynthesis supported by fatty acid oxidation in the mitochondrial fraction of human term placenta.
Topics: Acyl Coenzyme A; Adenine Nucleotides; Adenosine Triphosphate; Cholesterol; Fatty Acids; Female; Huma | 1983 |
Effect of ischemia on fatty acid metabolism in fetal lung.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fatty Acids; Female; Fetus; Ischemia; Kineti | 1983 |
Quantitative histochemical measurement of pyruvate and lactate in mouse oviduct during the estrous cycle.
Topics: Anaerobiosis; Animals; Estrus; Fallopian Tubes; Female; Histocytochemistry; Kinetics; L-Lactate Dehy | 1982 |
Effects of pregnancy and sex steroid administration on skeletal muscle metabolism in the rat.
Topics: Alanine; Animals; Estradiol; Female; Glucose; Glycerol; Insulin; Lactates; Lactic Acid; Muscles; Oxy | 1981 |
Fetal myocardial oxygen and carbohydrate consumption during acutely induced hypoxemia.
Topics: Animals; Blood Pressure; Coronary Circulation; Female; Fetus; Glucose; Heart; Heart Rate; Hypoxia; L | 1982 |
Fetal myocardial oxygen and carbohydrate metabolism in sustained hypoxemia in utero.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Coronary Vessels; Female; Fetus; Heart; Hypoxia; La | 1982 |
NAD(P)-dependent malic enzyme activity in human term placental mitochondria.
Topics: Cations; Female; Humans; In Vitro Techniques; Malate Dehydrogenase; Manganese; Mitochondria; NAD; NA | 1982 |
Comparison of pyruvate uptake by embryos derived from conception and non-conception natural cycles.
Topics: Embryo, Mammalian; Female; Fertilization in Vitro; Humans; Menstrual Cycle; Pregnancy; Pyruvates; Py | 1994 |
Transient rise of glucose uptake in the fetal rat brain after brief episodes of intrauterine ischemia.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Deoxyglucose; Energy Metabo | 1994 |
Properties of a lactate-induced relaxation in human placental arteries and veins.
Topics: Analysis of Variance; Arginine; Arteries; Colforsin; Cyanides; Dinoprost; Dose-Response Relationship | 1993 |
Glucose, galactose, and glutamine metabolism in pig isolated enterocytes during development.
Topics: Animals; Animals, Newborn; Animals, Suckling; Female; Galactose; Glucose; Glutamine; Glycogen; In Vi | 1994 |
Metabolism of pyruvate by pre-elongation sheep embryos and effect of pyruvate and lactate concentrations during culture in vitro.
Topics: Animals; Blastocyst; Culture Media; Embryonic and Fetal Development; Female; In Vitro Techniques; Ki | 1993 |
Uptake and metabolism of pyruvate and glucose by individual sheep preattachment embryos developed in vivo.
Topics: Animals; Blastocyst; Culture Techniques; Embryonic and Fetal Development; Embryonic Development; Fem | 1993 |
Energy economy in the pregnant human uterus at term: studies on arteriovenous differences in metabolites of carbohydrate, fat and nucleotides.
Topics: Adult; Arteries; Blood Glucose; Carbohydrates; Energy Metabolism; Fatty Acids, Nonesterified; Female | 1993 |
Uptake of L-lactate by cultured rat brain neurons.
Topics: Animals; Brain; Cell Membrane; Cells, Cultured; Coumaric Acids; Female; Hydrogen-Ion Concentration; | 1993 |
Glucose, pyruvate, and lactate concentrations in the blastocoel cavity of rat and mouse embryos.
Topics: Animals; Blastocyst; Body Fluids; Female; Fluorometry; Glucose; Lactates; Lactic Acid; Mice; Mice, I | 1993 |
Diabetes and embryonic malformations. Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos.
Topics: 3-Hydroxybutyric Acid; Animals; Congenital Abnormalities; Culture Techniques; Embryo, Mammalian; Fem | 1993 |
Selection criteria for human embryo transfer: a comparison of pyruvate uptake and morphology.
Topics: Adult; Blastocyst; Culture Techniques; Embryo Implantation; Embryo Transfer; Female; Humans; Pregnan | 1993 |
Metabolism and cell allocation during parthenogenetic preimplantation mouse development.
Topics: Animals; Blastomeres; Cell Count; Chromosomes; Cleavage Stage, Ovum; Ectoderm; Embryonic and Fetal D | 1996 |
Carbohydrate uptake by quiescent and reactivated mouse blastocysts.
Topics: Animals; Blastocyst; Cell Count; Cell Division; Embryo Implantation; Estradiol; Female; Glucose; Mal | 1996 |
Comparison of the lactate-pyruvate ratio during labour and delivery in singleton and twin pregnancy.
Topics: Female; Fetal Blood; Humans; Labor, Obstetric; Lactic Acid; Oxygen Consumption; Pregnancy; Pregnancy | 1997 |
Effect of perinatal asphyxia on systemic and intracerebral pH and glycolysis metabolism in the rat.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Chemistry; Brain Diseases; Corpus Striatum; Female; | 1997 |
Lactate, lactate/pyruvate ratio and catecholamine interrelations in cord blood at delivery in complicated pregnancies.
Topics: Asphyxia Neonatorum; Catecholamines; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; | 1998 |
Human embryo culture: back to nature.
Topics: Amino Acids; Body Fluids; Calcium; Chlorine; Culture Media; Electron Probe Microanalysis; Fallopian | 1998 |
Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
Topics: Animals; Blastocyst; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; Fe | 2000 |
Energy metabolism in preimplantation bovine embryos derived in vitro or in vivo.
Topics: Animals; Blastocyst; Carbon Dioxide; Cattle; Culture Media; Embryonic and Fetal Development; Energy | 2000 |
Effects of superovulated heifer diet type and quantity on relative mRNA abundances and pyruvate metabolism in recovered embryos.
Topics: Analysis of Variance; Animals; Cattle; Diet; Embryo, Mammalian; Female; Gestational Age; Globins; Pr | 2000 |
Effects of sodium pyruvate in nonserum maturation medium on maturation, fertilization, and subsequent development of bovine oocytes with or without cumulus cells.
Topics: Animals; Blastocyst; Cattle; Culture Media, Serum-Free; Female; Fertilization in Vitro; Glutathione; | 2000 |
Role of developmental factors in the switch from pyruvate to glucose as the major exogenous energy substrate in the preimplantation mouse embryo.
Topics: Amanitins; Animals; Blastocyst; Cell Division; Chorionic Gonadotropin; Culture Techniques; Cytochala | 1999 |
An unusual subcellular localization of GLUT1 and link with metabolism in oocytes and preimplantation mouse embryos.
Topics: Animals; Blastocyst; Blotting, Western; Cell Membrane; Cell Nucleus; Cells, Cultured; Embryo, Mammal | 2001 |
Development and viability of in vitro derived porcine blastocysts cultured in NCSU23 and G1.2/G2.2 sequential medium.
Topics: Animals; Blastocyst; Culture Media; Female; Fertilization in Vitro; Glucose; Male; Oocytes; Pregnanc | 2001 |
Inhibiting 3-phosphoglycerate kinase by EDTA stimulates the development of the cleavage stage mouse embryo.
Topics: Animals; Blastocyst; Cell Survival; Cells, Cultured; Chelating Agents; Cleavage Stage, Ovum; Edetic | 2001 |
Estimation of gluconeogenesis in newborn infants.
Topics: Amino Acids; Blood Glucose; Body Water; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Femal | 2001 |
Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential.
Topics: Blastocyst; Cryopreservation; Embryonic and Fetal Development; Female; Fertilization in Vitro; Gluco | 2001 |
Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons.
Topics: Animals; Astrocytes; Brain; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Coumaric Acids; D | 2001 |
Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.
Topics: Alanine; Animals; Arginine; Blood Glucose; Female; Fetal Blood; Gestational Age; Glucagon; Gluconeog | 2002 |
Use of energy substrates by various stage preimplantation pig embryos produced in vivo and in vitro.
Topics: Analysis of Variance; Animals; Blastocyst; Cell Survival; Cells, Cultured; Citric Acid Cycle; Female | 2002 |
Functional significance of gap junctional coupling in preimplantation development.
Topics: Animals; Apoptosis; Blastocyst; Connexin 30; Connexins; Female; Fluorescent Antibody Technique, Dire | 2002 |
Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Bacterial Infections; Blood Pressure; Brain; Cerebral Palsy; Encephalitis | 2002 |
Pregnancy complicated with lactate dehydrogenase M-subunit deficiency: the first case report.
Topics: Abdominal Pain; Adenosine Triphosphate; Adolescent; Cesarean Section; Dystocia; Female; Glycolysis; | 2002 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal | 2002 |
Prenatal diagnosis of systemic disorders of the respiratory chain in cultured amniocytes and chorionic villus fibroblasts by studying the formation of lactate and pyruvate from glucose.
Topics: Amnion; Cells, Cultured; Chorionic Villi; Cytochrome-c Oxidase Deficiency; Female; Fibroblasts; Gluc | 1992 |
Decrease of pyruvate dehydrogenase phosphatase activity in patients with congenital lactic acidemia.
Topics: Acidosis, Lactic; Child; Enzyme Activation; Female; Fibroblasts; Humans; Infant; Male; Mitochondria; | 1992 |
Influence of pregnancy and lactation on diurnal and seasonal changes in lactic acid and pyruvic acid levels and in values of pH, pCO2 and pO2 in the mare blood.
Topics: Animals; Carbon Dioxide; Circadian Rhythm; Female; Horses; Hydrogen-Ion Concentration; Lactates; Lac | 1991 |
Diurnal changes in lactic and pyruvic acid levels and pH values in foals during the first 13 weeks of their life and in their lactating mothers.
Topics: Animals; Animals, Newborn; Circadian Rhythm; Female; Horses; Hydrogen-Ion Concentration; Lactates; L | 1991 |
Culture of fetal alveolar epithelial type II cells in serum-free medium.
Topics: Animals; Biotin; Cell Division; Cells, Cultured; Choline; Culture Media, Serum-Free; DNA; Epithelial | 1991 |
Effect of lactate and beta-hydroxybutyrate infusions on brain metabolism in the fetal sheep.
Topics: 3-Hydroxybutyric Acid; Animals; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Female; Fet | 1990 |
Development and regulation of hepatocellular fatty acid synthesis towards term: studies in isolated fetal rat hepatocytes.
Topics: Animals; Caprylates; Cyclic AMP; Fatty Acids; Female; Insulin; Lactates; Lactic Acid; Liver; NAD; NA | 1990 |
Concentrations of nutrients in mouse oviduct fluid and their effects on embryo development and metabolism in vitro.
Topics: Animals; Body Fluids; Culture Media; Embryo, Mammalian; Embryonic and Fetal Development; Fallopian T | 1990 |
[Effects of various oxygen concentrations on metabolic performance of in vitro perfused human placentas].
Topics: Blood Glucose; Cell Hypoxia; Energy Metabolism; Female; Glycolysis; Humans; Lactates; Lactic Acid; O | 1990 |
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxy | 1989 |
A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1988 |
Insulin activation of lipogenesis in isolated mammary acini from lactating rats fed on a high-fat diet. Evidence that acetyl-CoA carboxylase is a site of action.
Topics: Acetates; Acetic Acid; Acetyl-CoA Carboxylase; Animals; Coumaric Acids; Cyclic AMP; Dietary Fats; En | 1987 |
[Blood levels of adenine nucleotides and lactic and pyruvic acids in pregnancy].
Topics: Adenine Nucleotides; Adult; Female; Humans; Lactates; Lactic Acid; Pregnancy; Pyruvates; Pyruvic Aci | 1985 |
Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs.
Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Female; Fetal Growth Retardation; Glycogen | 1988 |
Respiratory and metabolic responses of fetal and neonatal perfused livers to catecholamines and anoxia.
Topics: Animals; Animals, Newborn; Female; Gluconeogenesis; Glycolysis; Guinea Pigs; In Vitro Techniques; La | 1988 |
Net substrates balance across hindlimb in conscious rabbit during late pregnancy.
Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Hindlimb; Homeostasis; Insulin; | 1986 |
Placental glycolysis and energy metabolism in preeclampsia.
Topics: Adenine Nucleotides; Energy Metabolism; Female; Fetal Growth Retardation; Glycolysis; Humans; Lactat | 1987 |
[Experimental studies of the effect of propranolol on the metabolism of the human placenta with regard to the production of lactic and pyruvic acids].
Topics: Depression, Chemical; Female; Humans; In Vitro Techniques; Lactates; Lactic Acid; Placenta; Pregnanc | 1987 |
Stimulatory effect of ADP, ATP, NAD(P) on pyruvate production from malate by uncoupled human placental mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Female; Humans; Hydrogen-Ion Concentration; In Vitro | 1987 |
Branched-chain amino acid carbon and nitrogen arteriovenous concentration differences across the ovine fetal hindlimb.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Extremities; Female; Fetus; Lactates; Lactic Ac | 1987 |
Effect of glucose and insulin administration on hepatic adenylate energy charge and the cytosolic redox state in the neonates of normal and insulin-treated diabetic rats.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Animals, Newborn; Cytosol; Diabetes Mellitus, | 1985 |
Effects of alloxan-induced diabetes mellitus on the metabolism of the rat placenta.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransfe | 1986 |
Role of the availability of substrates on hepatic and renal gluconeogenesis in the fasted late pregnant rat.
Topics: Alanine; Animals; Carbon Radioisotopes; Fasting; Female; Gluconeogenesis; Glucose; Glycerol; In Vitr | 1986 |
[Indicators of exertion metabolism in parturients].
Topics: Female; Humans; Labor, Obstetric; Lactates; Lactic Acid; Oxygen Consumption; Physical Exertion; Preg | 1985 |
[Energy metabolism of the myometrium in pregnancy and labor].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Energy Metabolism; Fatty Aci | 1985 |
Effects of intravenous ritodrine on lactate and pyruvate levels: role of glycemia and anaerobiosis.
Topics: Anaerobiosis; Blood Glucose; Female; Humans; Lactates; Lactic Acid; Metabolism; Obstetric Labor, Pre | 1985 |