pyruvic acid has been researched along with Osteosarcoma in 5 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate this hypothesis, we compared the response to an anticancer agent chloroethylnitrosourea (CENU) of two transformed cell lines: HepG2 (hepatocarcinoma) with a partially differentiated phenotype and 143B (osteosarcoma) with an undifferentiated one." | 3.75 | Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy. ( Chevrollier, A; Demidem, A; Douay, O; Loiseau, D; Morvan, D; Reynier, P; Stepien, G, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tornin, J | 1 |
| Mateu-Sanz, M | 1 |
| RodrÃguez, A | 1 |
| Labay, C | 1 |
| RodrÃguez, R | 1 |
| Canal, C | 1 |
| Chen, K | 1 |
| Zhu, C | 1 |
| Cai, M | 1 |
| Fu, D | 1 |
| Cheng, B | 1 |
| Cai, Z | 1 |
| Li, G | 1 |
| Liu, J | 1 |
| Loiseau, D | 1 |
| Morvan, D | 1 |
| Chevrollier, A | 1 |
| Demidem, A | 1 |
| Douay, O | 1 |
| Reynier, P | 1 |
| Stepien, G | 1 |
| de Andrade, PB | 1 |
| Casimir, M | 1 |
| Maechler, P | 1 |
| Dunbar, DR | 1 |
| Moonie, PA | 1 |
| Zeviani, M | 1 |
| Holt, IJ | 1 |
5 other studies available for pyruvic acid and Osteosarcoma
| Article | Year |
|---|---|
Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; DNA Damage; Humans; Osteosarcoma | 2019 |
Integrative metabolome and transcriptome profiling reveals discordant glycolysis process between osteosarcoma and normal osteoblastic cells.
Topics: Biomarkers, Tumor; Case-Control Studies; Cyclic GMP-Dependent Protein Kinase Type I; Down-Regulation | 2014 |
Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy.
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Cell Differentiation; Cell Proliferation; Cell Re | 2009 |
Mitochondrial activation and the pyruvate paradox in a human cell line.
Topics: Adenosine Triphosphate; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line, Tumor; Cytoso | 2004 |
Complex I deficiency is associated with 3243G:C mitochondrial DNA in osteosarcoma cell cybrids.
Topics: Cell Fusion; DNA, Mitochondrial; Electron Transport Complex IV; Humans; Hybrid Cells; Lactates; Lact | 1996 |