pyruvic acid has been researched along with Neurocysticercosis in 1 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Neurocysticercosis: Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitazoxanide (NTZ) is an antifolate containing the pyrrolopyrimidine-based nucleus that exerts its antiprotozoal activity due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme which is essential to anaerobic energy metabolism." | 5.51 | Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci. ( Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC, 2019) |
| "Nitazoxanide (NTZ) is an antifolate containing the pyrrolopyrimidine-based nucleus that exerts its antiprotozoal activity due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme which is essential to anaerobic energy metabolism." | 1.51 | Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci. ( Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lima, NF | 1 |
| Picanço, GA | 1 |
| Alves, DSMM | 1 |
| Silva, LD | 1 |
| Isac, E | 1 |
| Costa, TL | 1 |
| Lino Junior, RS | 1 |
| Vinaud, MC | 1 |
1 other study available for pyruvic acid and Neurocysticercosis
| Article | Year |
|---|---|
Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci.
Topics: Administration, Oral; Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cysticercus; Ene | 2019 |