pyruvic acid has been researched along with Nerve Degeneration in 10 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harder, JM | 1 |
| Guymer, C | 1 |
| Wood, JPM | 1 |
| Daskalaki, E | 1 |
| Chidlow, G | 1 |
| Zhang, C | 1 |
| Balasubramanian, R | 1 |
| Cardozo, BH | 1 |
| Foxworth, NE | 1 |
| Deering, KE | 1 |
| Ouellette, TB | 1 |
| Montgomery, C | 1 |
| Wheelock, CE | 1 |
| Casson, RJ | 1 |
| Williams, PA | 1 |
| John, SWM | 1 |
| Radu, AG | 1 |
| Torch, S | 1 |
| Fauvelle, F | 1 |
| Pernet-Gallay, K | 1 |
| Lucas, A | 1 |
| Blervaque, R | 1 |
| Delmas, V | 1 |
| Schlattner, U | 1 |
| Lafanechère, L | 1 |
| Hainaut, P | 1 |
| Tricaud, N | 1 |
| Pingault, V | 1 |
| Bondurand, N | 1 |
| Bardeesy, N | 1 |
| Larue, L | 1 |
| Thibert, C | 1 |
| Billaud, M | 1 |
| Netzahualcoyotzi, C | 1 |
| Tapia, R | 3 |
| Santa-Cruz, LD | 1 |
| Guerrero-Castillo, S | 1 |
| Uribe-Carvajal, S | 1 |
| Izumi, Y | 1 |
| Zorumski, CF | 1 |
| Carvalho, AS | 1 |
| Torres, LB | 1 |
| Persike, DS | 1 |
| Fernandes, MJ | 1 |
| Amado, D | 1 |
| Naffah-Mazzacoratti, Mda G | 1 |
| Cavalheiro, EA | 1 |
| da Silva, AV | 1 |
| Obel, LF | 1 |
| Andersen, KM | 1 |
| Bak, LK | 1 |
| Schousboe, A | 1 |
| Waagepetersen, HS | 1 |
| Fernandez-Gomez, FJ | 1 |
| Pastor, MD | 1 |
| Garcia-Martinez, EM | 1 |
| Melero-Fernandez de Mera, R | 1 |
| Gou-Fabregas, M | 1 |
| Gomez-Lazaro, M | 1 |
| Calvo, S | 1 |
| Soler, RM | 1 |
| Galindo, MF | 1 |
| Jordán, J | 1 |
| Corona, JC | 1 |
| Massieu, L | 1 |
| Del Río, P | 1 |
| Montiel, T | 1 |
10 other studies available for pyruvic acid and Nerve Degeneration
| Article | Year |
|---|---|
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
Topics: Animals; Disease Models, Animal; Glaucoma; Glucose; Intraocular Pressure; Mice, Inbred C57BL; Mice, | 2020 |
LKB1 specifies neural crest cell fates through pyruvate-alanine cycling.
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Cell Differentiation; Energy Metabolism; Enteric Ne | 2019 |
Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Ascorbic Acid; Cell | 2015 |
Mitochondrial Dysfunction during the Early Stages of Excitotoxic Spinal Motor Neuron Degeneration in Vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Excitator | 2016 |
Neuroprotective effects of pyruvate following NMDA-mediated excitotoxic insults in hippocampal slices.
Topics: Adenosine Triphosphate; Aging; Animals; Brain Injuries; CA1 Region, Hippocampal; Enzyme Inhibitors; | 2010 |
Neuroprotective effect of pyruvate and oxaloacetate during pilocarpine induced status epilepticus in rats.
Topics: Animals; Disease Models, Animal; Male; Nerve Degeneration; Neuroprotective Agents; Oxaloacetic Acid; | 2011 |
Effects of adrenergic agents on intracellular Ca2+ homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity.
Topics: Adrenergic Agents; Animals; Astrocytes; Calcium; Carboxy-Lyases; Citric Acid Cycle; Cytoplasm; Decar | 2012 |
Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Cells, Cultured; Cerebellar Cortex; Cytoprotecti | 2006 |
Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Calcium Sig | 2007 |
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acid Transport System X-AG; Animals; Brain Ischemia; Con | 2001 |