Page last updated: 2024-10-20

pyruvic acid and Muscle Disorders

pyruvic acid has been researched along with Muscle Disorders in 17 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Research Excerpts

ExcerptRelevanceReference
"Atorvastatin treatment resulted in a rise in both CK (2X) and myoglobin (6X) level with graded degrees of muscle necrosis."1.43Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model. ( Abdallah, D; El-Ganainy, SO; El-Khatib, AS; El-Mallah, A; Khattab, MM; Mohy El-Din, MM, 2016)
"Many neuromuscular diseases are inherited or breed-associated, and DNA-based tests may already be established or may be feasible to develop after the disorder has been accurately characterized."1.36Routine and specialized laboratory testing for the diagnosis of neuromuscular diseases in dogs and cats. ( Shelton, GD, 2010)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's2 (11.76)18.2507
2000's1 (5.88)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Semeraro, M1
Boenzi, S1
Carrozzo, R1
Diodato, D1
Martinelli, D1
Olivieri, G1
Antonetti, G1
Sacchetti, E1
Catesini, G1
Rizzo, C1
Dionisi-Vici, C1
El-Ganainy, SO1
El-Mallah, A1
Abdallah, D1
Khattab, MM1
Mohy El-Din, MM1
El-Khatib, AS1
Shelton, GD2
Mouadil, A1
Debout, C1
Read, MH1
Morello, R1
Allouche, S1
Chapon, F1
Ernberg, M1
Castrillon, EE1
Ghafouri, B1
Larsson, B1
Gerdle, B1
List, T1
Svensson, P1
PANSINI, R3
NOTARISTEFANO, M1
SOZIO, N2
FERSINI, C1
ISRAELS, S1
HAWORTH, JC1
GOURLEY, B1
FORD, JD1
LICHY, J1
HORAK, M1
JICHA, J1
ZDRAHAL, L1
Sattler, UG1
Walenta, S1
Mueller-Klieser, W1
Letellier, T1
Malgat, M1
Mazat, JP1
Platt, SR1
Chrisman, CL1
Toyoda, M1
Sakuragawa, N1
Arai, Y1
Yoshikawa, H1
Sugai, K1
Arima, M1
Hara, T1
Iio, M1
Satoyoshi, E1
Naito, E1
Kuroda, Y1
Toshima, K1
Takeda, E1
Saijo, T1
Kobashi, H1
Yokota, I1
Ito, M1
Tatsumi, C1
Takahashi, M1
Yorifuji, S1
Nishikawa, Y1
Kitaguchi, M1
Hashimoto, S1
Tarui, S1
Fischer, JC1
Ruitenbeek, W1
Stadhouders, AM1
Trijbels, JM1
Sengers, RC1
Janssen, AJ1
Veerkamp, JH1

Trials

1 trial available for pyruvic acid and Muscle Disorders

ArticleYear
Experimental myalgia induced by repeated infusion of acidic saline into the human masseter muscle does not cause the release of algesic substances.
    European journal of pain (London, England), 2013, Volume: 17, Issue:4

    Topics: Acids; Adult; Female; Glucose; Glutamic Acid; Humans; Hyperalgesia; Lactic Acid; Male; Masseter Musc

2013

Other Studies

16 other studies available for pyruvic acid and Muscle Disorders

ArticleYear
The urinary organic acids profile in single large-scale mitochondrial DNA deletion disorders.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 481

    Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Child; Child, Preschool; Cong

2018
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model.
    Toxicology, 2016, 06-01, Volume: 359-360

    Topics: Adenosine Triphosphate; Animals; Atorvastatin; Creatine Kinase; Disease Models, Animal; Hydroxymethy

2016
Routine and specialized laboratory testing for the diagnosis of neuromuscular diseases in dogs and cats.
    Veterinary clinical pathology, 2010, Volume: 39, Issue:3

    Topics: Animals; Autoantibodies; Biopsy; Cat Diseases; Cats; Clinical Laboratory Techniques; Creatine Kinase

2010
Blood metabolite data in response to maximal exercise in healthy subjects.
    Clinical physiology and functional imaging, 2012, Volume: 32, Issue:4

    Topics: Adult; Ammonia; Biomarkers; Energy Metabolism; Exercise; Exercise Test; Exercise Tolerance; Female;

2012
[Research on muscle physiopathology in man. II. Variations in the endogenous blood alcohol, pyruvic acid and glucose in the venous circulation after ATP load in muscle diseases].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Blood; Blood Glucose; Disease; Ethanol; Glucose; Humans; Male; Muscles; Musc

1953
[Research on muscle physiopathology in man. I. Variations in the endogenous blood alcohol, pyruvic acid and glucose in the superficial venous circulation after insulin load and after glucose load in muscle diseases].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Alcohols; Blood; Blood Glucose; Catabolite Repression; Disease; Ethanol; Glucose; Humans; Insulin; M

1953
[Research on muscle physiopathology in man. III. Variations in the endogenous blood alcohol, pyruvic acid and glucose in the venous circulation after cocarboxylase load in muscle diseases].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Blood; Blood Glucose; Disease; Ethanol; Glucose; Humans; Male; Muscles; Muscular Diseases; Pyruvates

1953
CHRONIC ACIDOSIS DUE TO AN ERROR IN LACTATE AND PYRUVATE METABOLISM. REPORT OF TWO CASES.
    Pediatrics, 1964, Volume: 34

    Topics: Acetoacetates; Acidosis; Blood; Blood Gas Analysis; Carbohydrate Metabolism; Carbohydrate Metabolism

1964
[The transaminase of glutmic-pyruvic acid (GPT) in myopathies].
    Ceskoslovenska neurologie, 1961, Volume: 24

    Topics: Humans; Muscular Diseases; Muscular Dystrophies; Pyruvic Acid; Transaminases

1961
A bioluminescence technique for quantitative and structure-associated imaging of pyruvate.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:1

    Topics: Biological Assay; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Diagnostic Imaging; Froze

2007
Control of oxidative phosphorylation in rat muscle mitochondria: implications for mitochondrial myopathies.
    Biochimica et biophysica acta, 1993, Feb-08, Volume: 1141, Issue:1

    Topics: Animals; Electron Transport Complex III; Electron Transport Complex IV; Hindlimb; Malates; Mitochond

1993
Lipid storage myopathy in a cocker spaniel.
    The Journal of small animal practice, 1999, Volume: 40, Issue:1

    Topics: Acetoacetates; Animals; Dog Diseases; Dogs; Lactic Acid; Lipid Metabolism, Inborn Errors; Male; Musc

1999
Positron emission tomography using pyruvate-1-11C in two cases of mitochondrial encephalomyopathy.
    Annals of nuclear medicine, 1989, Volume: 3, Issue:2

    Topics: Brain Diseases; Carbon Radioisotopes; Child; Female; Humans; Infant; Mitochondria; Mitochondria, Mus

1989
Effect of sodium dichloroacetate on human pyruvate metabolism.
    Brain & development, 1989, Volume: 11, Issue:3

    Topics: Acetates; Acidosis, Lactic; Adolescent; Blood Platelets; Dichloroacetic Acid; Humans; Male; Muscular

1989
Mitochondrial encephalomyopathy with sleep apnea.
    European neurology, 1988, Volume: 28, Issue:2

    Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Di

1988
Investigation of mitochondrial metabolism in small human skeletal muscle biopsy specimens. Improvement of preparation procedure.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Jan-15, Volume: 145, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Cell Fractionation; Child; Humans;

1985