pyruvic acid has been researched along with Muscle Contraction in 49 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We measured active stress, myosin phosphorylation, O2 consumption, and tissue ATP content in bovine tracheal smooth muscle activated by K+ depolarization when glucose was replaced by pyruvate and when oxidative metabolism was inhibited by hypoxia or uncoupled by 2,4-dinitrophenol." | 3.68 | Effects of substrate and inhibition of oxidative metabolism on contraction and myosin phosphorylation in ASM. ( Hai, CM; Kim, E; Reyes, V; Wallach, SJ; Watson, C; Xu, J, 1993) |
| "Investigate proprioceptive allodynia after experimental tooth clenching exercises (study II)." | 2.78 | Experimental tooth clenching. A model for studying mechanisms of muscle pain. ( Dawson, A, 2013) |
| "Five patients with McArdle's disease and five patients with mitochondrial myopathies performed the same incremental maximal exercise test." | 1.28 | Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies. ( Camus, F; Chaussain, M; Defoligny, C; Eymard, B; Fardeau, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.53) | 18.7374 |
| 1990's | 17 (34.69) | 18.2507 |
| 2000's | 10 (20.41) | 29.6817 |
| 2010's | 8 (16.33) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Bertrand-Gaday, C | 1 |
| Letheule, M | 1 |
| Blanchet, E | 1 |
| Vernus, B | 1 |
| Pessemesse, L | 1 |
| Bonnet-Garnier, A | 1 |
| Bonnieu, A | 1 |
| Casas, F | 1 |
| Urai, M | 1 |
| Aizawa, T | 1 |
| Imamura, K | 1 |
| Hamamoto, H | 1 |
| Sekimizu, K | 1 |
| Dawson, A | 2 |
| Torres, CA | 1 |
| Varian, KD | 1 |
| Canan, CH | 1 |
| Davis, JP | 1 |
| Janssen, PM | 1 |
| Ghafouri, B | 1 |
| Gerdle, B | 1 |
| List, T | 1 |
| Svensson, P | 1 |
| Ernberg, M | 1 |
| Pant, M | 1 |
| Sopariwala, DH | 1 |
| Bal, NC | 1 |
| Lowe, J | 1 |
| Delfín, DA | 1 |
| Rafael-Fortney, J | 1 |
| Periasamy, M | 1 |
| Vila, MC | 1 |
| Rayavarapu, S | 1 |
| Hogarth, MW | 1 |
| Van der Meulen, JH | 1 |
| Horn, A | 1 |
| Defour, A | 1 |
| Takeda, S | 1 |
| Brown, KJ | 1 |
| Hathout, Y | 1 |
| Nagaraju, K | 1 |
| Jaiswal, JK | 1 |
| Gao, Q | 1 |
| Wolin, MS | 2 |
| Thyfault, JP | 1 |
| Cree, MG | 1 |
| Tapscott, EB | 1 |
| Bell, JA | 1 |
| Koves, TR | 1 |
| Ilkayeva, O | 1 |
| Wolfe, RR | 1 |
| Dohm, GL | 1 |
| Muoio, DM | 1 |
| Mouadil, A | 1 |
| Debout, C | 1 |
| Read, MH | 1 |
| Morello, R | 1 |
| Allouche, S | 1 |
| Chapon, F | 1 |
| Diolez, P | 1 |
| Raffard, G | 1 |
| Simon, C | 1 |
| Leducq, N | 1 |
| Dos, SP | 1 |
| Canioni, P | 1 |
| Rosendal, L | 1 |
| Blangsted, AK | 1 |
| Kristiansen, J | 1 |
| Søgaard, K | 1 |
| Langberg, H | 1 |
| Sjøgaard, G | 1 |
| Kjaer, M | 1 |
| Nasu, T | 2 |
| Takahashi, K | 1 |
| Gupte, SA | 1 |
| Fernström, M | 1 |
| Bakkman, L | 1 |
| Tonkonogi, M | 1 |
| Shabalina, IG | 1 |
| Rozhdestvenskaya, Z | 1 |
| Mattsson, CM | 1 |
| Enqvist, JK | 1 |
| Ekblom, B | 1 |
| Sahlin, K | 1 |
| Puppi, A | 1 |
| Dely, M | 1 |
| Lubek, BM | 1 |
| Mainwood, GW | 1 |
| Leijendekker, WJ | 1 |
| van Hardeveld, C | 1 |
| Kassenaar, AA | 1 |
| Abe, M | 1 |
| Furukawa, T | 1 |
| Watt, PW | 1 |
| Gladden, LB | 2 |
| Hundal, HS | 1 |
| Crawford, RE | 2 |
| Longhurst, PA | 1 |
| Briscoe, JA | 1 |
| Leggett, RE | 1 |
| Samadzadeh, S | 1 |
| Levin, RM | 2 |
| Webster, MJ | 1 |
| Duhaylongsod, FG | 1 |
| Griebel, JA | 1 |
| Bacon, DS | 1 |
| Wolfe, WG | 1 |
| Piantadosi, CA | 1 |
| Phillips, SK | 1 |
| Wiseman, RW | 1 |
| Woledge, RC | 1 |
| Kushmerick, MJ | 1 |
| Hai, CM | 1 |
| Watson, C | 1 |
| Wallach, SJ | 1 |
| Reyes, V | 1 |
| Kim, E | 1 |
| Xu, J | 1 |
| Dengler, R | 1 |
| Wohlfarth, K | 1 |
| Zierz, S | 1 |
| Jobges, M | 1 |
| Schubert, M | 1 |
| Hardin, CD | 1 |
| Roberts, TM | 1 |
| Barron, JT | 1 |
| Gu, L | 1 |
| Parrillo, JE | 1 |
| Young, ME | 1 |
| Leighton, B | 1 |
| Stone, MH | 1 |
| Sanborn, K | 1 |
| Smith, LL | 1 |
| O'Bryant, HS | 1 |
| Hoke, T | 1 |
| Utter, AC | 1 |
| Johnson, RL | 1 |
| Boros, R | 1 |
| Hruby, J | 1 |
| Pierce, KC | 1 |
| Stone, ME | 1 |
| Garner, B | 1 |
| Constantin-Teodosiu, D | 1 |
| Greenhaff, PL | 1 |
| Cieslar, JH | 2 |
| Dobson, GP | 2 |
| Posterino, GS | 1 |
| Fryer, MW | 1 |
| Ido, Y | 1 |
| Chang, K | 1 |
| Woolsey, TA | 1 |
| Williamson, JR | 1 |
| Chaussain, M | 1 |
| Camus, F | 1 |
| Defoligny, C | 1 |
| Eymard, B | 1 |
| Fardeau, M | 1 |
| Ström, D | 1 |
| Holm, S | 2 |
| Zakimi, S | 1 |
| Shibata, H | 1 |
| Hypolite, JA | 1 |
| Wein, AJ | 1 |
| Haugaard, N | 1 |
| Maass, U | 1 |
| Goller, B | 1 |
| Grote, R | 1 |
| Alexander, K | 1 |
| Challiss, RA | 1 |
| Vranic, M | 1 |
| Radda, GK | 1 |
| Wendt, IR | 1 |
| Rexroth, W | 1 |
| Isgro, F | 1 |
| Koeth, T | 1 |
| Manzl, G | 1 |
| Weicker, H | 1 |
| Shiota, M | 1 |
| Sugano, T | 1 |
| Spriet, LL | 1 |
| Söderlund, K | 1 |
| Bergström, M | 1 |
| Hultman, E | 1 |
| Brooks, GA | 1 |
| Fagan, JM | 1 |
| Goldberg, AL | 1 |
| Elander, A | 1 |
| Idström, JP | 1 |
| Scherstén, T | 1 |
| Bylund-Fellenius, AC | 1 |
| Valentini, FA | 1 |
| Nelson, PP | 1 |
3 reviews available for pyruvic acid and Muscle Contraction
| Article | Year |
|---|---|
Tissue redox-state potential (E'0)--as regulator of physiological processes.
Topics: Aging; Animals; Biological Transport, Active; Blood Physiological Phenomena; Cell Membrane; Cell Phy | 1983 |
The tricarboxylic acid cycle in human skeletal muscle: is there a role for nutritional intervention?
Topics: Citric Acid Cycle; Dietary Supplements; Energy Metabolism; Glutamine; Humans; Muscle Contraction; Mu | 1999 |
Anaerobic threshold: review of the concept and directions for future research.
Topics: Acidosis; Anaerobiosis; Animals; Glycolysis; Humans; Kinetics; L-Lactate Dehydrogenase; Lactates; La | 1985 |
3 trials available for pyruvic acid and Muscle Contraction
| Article | Year |
|---|---|
Experimental tooth clenching. A model for studying mechanisms of muscle pain.
Topics: Adult; Bruxism; Case-Control Studies; Cross-Over Studies; Female; Follow-Up Studies; Glutamic Acid; | 2013 |
Pain and intramuscular release of algesic substances in the masseter muscle after experimental tooth-clenching exercises in healthy subjects.
Topics: Adult; Bite Force; Bruxism; Chi-Square Distribution; Cross-Over Studies; Facial Pain; Female; Glutam | 2013 |
Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players.
Topics: Adolescent; Anaerobiosis; Body Composition; Body Weight; Creatine; Dietary Supplements; Humans; Male | 1999 |
43 other studies available for pyruvic acid and Muscle Contraction
| Article | Year |
|---|---|
Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood.
Topics: Acetylation; Animals; Carbohydrate Metabolism; Cytokines; Disease Models, Animal; Embryo, Mammalian; | 2020 |
Characterization of the chemical structure and innate immune-stimulating activity of an extracellular polysaccharide from Rhizobium sp. strain M2 screened using a silkworm muscle contraction assay.
Topics: Adjuvants, Immunologic; Animals; Bombyx; Galactose; Glucose; Immunity, Innate; Larva; Magnetic Reson | 2017 |
The positive inotropic effect of pyruvate involves an increase in myofilament calcium sensitivity.
Topics: Animals; Calcium; Male; Muscle Contraction; Myofibrils; Pyruvic Acid; Rabbits; Sarcoplasmic Reticulu | 2013 |
Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.
Topics: Animals; Disease Models, Animal; Dynamins; Dystrophin; Energy Metabolism; Glucose; GTP Phosphohydrol | 2015 |
Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy.
Topics: Animals; Cell Line; Cell Membrane; Dysferlin; Dystrophin; Fluorescence Resonance Energy Transfer; In | 2017 |
Effects of hypoxia on relationships between cytosolic and mitochondrial NAD(P)H redox and superoxide generation in coronary arterial smooth muscle.
Topics: Animals; Cattle; Coronary Vessels; Cytosol; Fluorescent Dyes; Hypoxia; In Vitro Techniques; Lactic A | 2008 |
Metabolic profiling of muscle contraction in lean compared with obese rodents.
Topics: Acetyl-CoA Carboxylase; Animals; Biological Transport; Carnitine; Glucose; Glycogen; Lactic Acid; Li | 2010 |
Blood metabolite data in response to maximal exercise in healthy subjects.
Topics: Adult; Ammonia; Biomarkers; Energy Metabolism; Exercise; Exercise Test; Exercise Tolerance; Female; | 2012 |
Mitochondria do not control heart bioenergetics.
Topics: Adenosine Triphosphate; Animals; Calcium; Energy Metabolism; Glucose; Homeostasis; In Vitro Techniqu | 2002 |
Interstitial muscle lactate, pyruvate and potassium dynamics in the trapezius muscle during repetitive low-force arm movements, measured with microdialysis.
Topics: Adult; Arm; Electromyography; Extracellular Space; Humans; Lactic Acid; Male; Microdialysis; Movemen | 2004 |
Effects of ouabain on contractions induced by manganese ions in C2+a-free, isotonic solutions with varying concentrations of K+ in guinea-pig taenia coli.
Topics: Animals; Calcium; Calcium Channel Blockers; Colon; Electrochemistry; Enzyme Inhibitors; Guinea Pigs; | 2005 |
Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Signaling | 2006 |
Reduced efficiency, but increased fat oxidation, in mitochondria from human skeletal muscle after 24-h ultraendurance exercise.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Cell Respiration; Exercise; Fatty Acids; Human | 2007 |
Lactate and pyruvate production in isolated thiamine-deficient rat diaphragm strips.
Topics: Animals; Diaphragm; Fatigue; Glucose; Glycolysis; Hydrogen; Hypoxia; In Vitro Techniques; Lactates; | 1984 |
The influence of the thyroid state on energy turnover during tetanic stimulation in the fast-twitch (mixed type) muscle of rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Hydrogen-Ion Concentratio | 1983 |
Spontaneous rhythmicity induced by glucose removal in the guinea-pig tracheal smooth muscle.
Topics: 3-O-Methylglucose; Adenosine Triphosphate; Animals; Female; Glucose; Guinea Pigs; In Vitro Technique | 1983 |
Effects of flow and contraction on lactate transport in the perfused rat hindlimb.
Topics: Animals; Biological Transport; Coumaric Acids; Electric Stimulation; Female; Lactates; Lactic Acid; | 1994 |
The influence of diabetes mellitus on glucose utilization by the rat urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Body Weight; Chromatography, Hi | 1993 |
Effect of lactate concentration and metabolic rate on net lactate uptake by canine skeletal muscle.
Topics: Animals; Dogs; Electric Stimulation; Female; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Ma | 1994 |
Effects of muscle contraction on cytochrome a,a3 redox state.
Topics: Animals; Cytochrome a Group; Dogs; Electric Stimulation; Electron Transport Complex IV; Lactates; Mi | 1993 |
The effect of metabolic fuel on force production and resting inorganic phosphate levels in mouse skeletal muscle.
Topics: Animals; Electric Stimulation; Glucose; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice | 1993 |
Effects of substrate and inhibition of oxidative metabolism on contraction and myosin phosphorylation in ASM.
Topics: 2,4-Dinitrophenol; Analysis of Variance; Animals; Cattle; Dinitrophenols; Glucose; Hypoxia; Isometri | 1993 |
Muscle fatigue, lactate, and pyruvate in mitochondrial myopathy with progressive external ophthalmoplegia.
Topics: Action Potentials; Adolescent; Adult; Aged; Exercise Test; Female; Humans; Lactates; Lactic Acid; Ma | 1996 |
Differential regulation of glucose and glycogen metabolism in vascular smooth muscle by exogenous substrates.
Topics: Acetates; Animals; Carbon Isotopes; Carotid Arteries; Glucose; Glycogen; Isometric Contraction; Lact | 1997 |
Cytoplasmic redox potential affects energetics and contractile reactivity of vascular smooth muscle.
Topics: Aerobiosis; Animals; Calcium; Caprylates; Carotid Arteries; Citric Acid Cycle; Cytoplasm; Energy Met | 1997 |
Fuel oxidation in skeletal muscle is increased by nitric oxide/cGMP--evidence for involvement of cGMP-dependent protein kinase.
Topics: Aminoquinolines; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gluco | 1998 |
Free [ADP] and aerobic muscle work follow at least second order kinetics in rat gastrocnemius in vivo.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aerobiosis; Animals; Electric Stimulation; Energy Met | 2000 |
Effects of high myoplasmic L-lactate concentration on E-C coupling in mammalian skeletal muscle.
Topics: Animals; Calcium; Diffusion; Electrophysiology; Hydrogen-Ion Concentration; In Vitro Techniques; Lac | 2000 |
NADH: sensor of blood flow need in brain, muscle, and other tissues.
Topics: Animals; Brain; Cytosol; Lactic Acid; Muscle Contraction; Muscles; NAD; Physical Conditioning, Anima | 2001 |
Force reduction uncoupled from pH and H(2)PO(-)(4) in rat gastrocnemius in vivo with continuous 2-Hz stimulation.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Glycogen; Hydrogen-Ion Concentration; Lactic | 2001 |
Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies.
Topics: Adult; Alanine; Ammonia; Energy Metabolism; Exercise Test; Exercise Tolerance; Female; Glycogen Stor | 1992 |
Bite-force development, metabolic and circulatory response to electrical stimulation in the canine and porcine masseter muscles.
Topics: Animals; Bite Force; Dogs; Electric Stimulation; Energy Metabolism; Female; Glucose; Glycogen; Lacta | 1992 |
The recovery from the relaxant effect by ouabain and the metabolic dependency of K+ contractions in guinea-pig taenia coli.
Topics: Animals; Colon; Guinea Pigs; Hydrogen-Ion Concentration; Isotonic Solutions; Kinetics; Lactates; Lac | 1991 |
Role of substrates in the maintenance of contractility of the rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Glucose; Malates; Male; Muscle Contraction; M | 1991 |
[Biochemical effects of discontinuous muscle work in arterial occlusive disease].
Topics: Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Lactates; Lactic Acid; Leg; Male; Midd | 1990 |
Bioenergetic changes during contraction and recovery in diabetic rat skeletal muscle.
Topics: Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Energy Metabolism; Glycogen; Hydroge | 1989 |
Effects of substrate and hypoxia on smooth muscle metabolism and contraction.
Topics: Anaerobiosis; Animals; Energy Metabolism; Female; Glucose; Lactates; Lactic Acid; Muscle Contraction | 1989 |
Influence of peripheral arterial occlusive disease on muscular metabolism. Part 2: Changes in pyruvate, alanine, and urea concentration in femoral blood.
Topics: Alanine; Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Leg; Muscle Contraction; Musc | 1989 |
Characteristics of rat hindlimbs perfused with erythrocyte- and albumin-free medium.
Topics: Adenine Nucleotides; Albumins; Animals; Bicarbonates; Buffers; Catecholamines; Erythrocytes; Female; | 1986 |
Skeletal muscle glycogenolysis, glycolysis, and pH during electrical stimulation in men.
Topics: Adult; Electric Stimulation; Glycogen; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lac | 1987 |
The rate of protein degradation in isolated skeletal muscle does not correlate with reduction-oxidation status.
Topics: Animals; Calcimycin; Calcium; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Male; Muscle Cont | 1985 |
Metabolic adaptation to reduced muscle blood flow. II. Mechanisms and beneficial effects.
Topics: Adaptation, Physiological; Adenine Nucleotides; Animals; Creatine; Electric Stimulation; Female; Gly | 1985 |
Mathematical model of muscular fatigue. II. Changes of metabolites level and of force during exercise in relation to a fatigability parameter.
Topics: Adenosine Triphosphate; Calcium; Computers; Energy Metabolism; Humans; Hydrogen-Ion Concentration; L | 1985 |