pyruvic acid has been researched along with Multiple Sclerosis in 6 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind placebo-controlled crossover study of ten patients with multiple sclerosis, we found amantadine hydrochloride therapy to be effective in improving fatigability in six." | 9.06 | Amantadine, fatigue, and multiple sclerosis. ( Appenzeller, O; Rosenberg, GA, 1988) |
| "In a double-blind placebo-controlled crossover study of ten patients with multiple sclerosis, we found amantadine hydrochloride therapy to be effective in improving fatigability in six." | 5.06 | Amantadine, fatigue, and multiple sclerosis. ( Appenzeller, O; Rosenberg, GA, 1988) |
| "Leigh's disease is a mitochondrial disease of infancy and early childhood, and is rare in adults." | 1.32 | An adult case of Leigh disease. ( Brinar, V; Djakovic, V; Malojcic, B; Poser, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BAUER, H | 1 |
| JOHNOVA, B | 2 |
| SERCL, M | 2 |
| CENDROWSKI, W | 1 |
| GROTT, E | 1 |
| PRUSINSKI, A | 1 |
| SZCZECINSKA, O | 1 |
| Malojcic, B | 1 |
| Brinar, V | 1 |
| Poser, C | 1 |
| Djakovic, V | 1 |
| Rosenberg, GA | 1 |
| Appenzeller, O | 1 |
1 trial available for pyruvic acid and Multiple Sclerosis
| Article | Year |
|---|---|
Amantadine, fatigue, and multiple sclerosis.
Topics: Amantadine; beta-Endorphin; beta-Lipotropin; Disability Evaluation; Fatigue; Humans; Lactates; Lacti | 1988 |
5 other studies available for pyruvic acid and Multiple Sclerosis
| Article | Year |
|---|---|
[Pyruvic acid concentration in blood in multiple sclerosis and in control cases; comparative studies on the methods and clinical significance of pyruvic acid determination in blood].
Topics: Blood; Humans; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1956 |
[Pyruvic acid metabolism in a case of multiple sclerosis].
Topics: Biochemical Phenomena; Humans; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1956 |
[Pyruvic acid metabolism in a case of multiple sclerosis].
Topics: Biochemical Phenomena; Humans; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1956 |
[Pyruvic acid metabolism in a case of multiple sclerosis].
Topics: Biochemical Phenomena; Humans; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1956 |
[Pyruvic acid metabolism in a case of multiple sclerosis].
Topics: Biochemical Phenomena; Humans; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1956 |
[Blood pyruvic acid in patients with multiple sclerosis].
Topics: Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1960 |
[On the problem of the treatment of multiple sclerosis with D-860 with special reference to the behavior of pyruvic acid].
Topics: Multiple Sclerosis; Pyruvates; Pyruvic Acid; Tolbutamide | 1962 |
An adult case of Leigh disease.
Topics: Adult; Brain; Cerebellum; Convalescence; Diagnosis, Differential; Electrocardiography; Electroenceph | 2004 |