pyruvic acid has been researched along with Liver Steatosis in 12 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protection against fatty liver is partially recapitulated by the systemic administration of low-dose carboxyatractyloside, a specific inhibitor of ANT." | 1.46 | Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. ( Cho, J; Choi, CS; Chun, SK; Han, C; Joseph, AM; Kalavalapalli, S; Kim, JS; Lee, HY; Lee, YJ; Mathews, CE; Morgan, D; Oh, SP; Park, HJ; Park, SY; Shiratsuchi, T; Someya, S; Sunny, NE; Terada, N; Wohlgemuth, SE; Zhang, Y, 2017) |
| "Treatment with ezetimibe reduced hepatic steatosis, insulin levels, and glucose production from pyruvate in mice fed the high-fat diet, suggesting a reduction of insulin resistance in the liver." | 1.39 | Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet. ( Kashiwagi, A; Kume, S; Maegawa, H; Maeno, Y; Morino, K; Nagai, Y; Nishio, Y; Sekine, O; Ugi, S; Ushio, M; Yoshizaki, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mu, K | 1 |
| Sun, Y | 1 |
| Zhao, Y | 1 |
| Zhao, T | 1 |
| Li, Q | 1 |
| Zhang, M | 1 |
| Li, H | 1 |
| Zhang, R | 1 |
| Hu, C | 1 |
| Wang, C | 1 |
| Jia, W | 1 |
| Morris, EM | 1 |
| McCoin, CS | 1 |
| Allen, JA | 1 |
| Gastecki, ML | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Fletcher, JA | 1 |
| Fu, X | 1 |
| Ding, WX | 1 |
| Burgess, SC | 1 |
| Rector, RS | 2 |
| Thyfault, JP | 2 |
| Nie, L | 1 |
| Yuan, XL | 1 |
| Jiang, KT | 1 |
| Jiang, YH | 1 |
| Yuan, J | 1 |
| Luo, L | 1 |
| Cui, SW | 1 |
| Sun, C | 1 |
| Maeda Júnior, AS | 1 |
| Constantin, J | 1 |
| Utsunomiya, KS | 1 |
| Gilglioni, EH | 1 |
| Gasparin, FRS | 1 |
| Carreño, FO | 1 |
| de Moraes, SMF | 1 |
| Rocha, M | 1 |
| Natali, MRM | 1 |
| Ghizoni, CVC | 1 |
| Bracht, A | 1 |
| Ishii-Iwamoto, EL | 1 |
| Constantin, RP | 1 |
| Ushio, M | 1 |
| Nishio, Y | 1 |
| Sekine, O | 1 |
| Nagai, Y | 1 |
| Maeno, Y | 1 |
| Ugi, S | 1 |
| Yoshizaki, T | 1 |
| Morino, K | 1 |
| Kume, S | 1 |
| Kashiwagi, A | 1 |
| Maegawa, H | 1 |
| Aroor, AR | 1 |
| Habibi, J | 1 |
| Ford, DA | 1 |
| Nistala, R | 1 |
| Lastra, G | 1 |
| Manrique, C | 1 |
| Dunham, MM | 1 |
| Ford, KD | 1 |
| Parks, EJ | 1 |
| Sowers, JR | 1 |
| Go, Y | 1 |
| Jeong, JY | 1 |
| Jeoung, NH | 1 |
| Jeon, JH | 1 |
| Park, BY | 1 |
| Kang, HJ | 1 |
| Ha, CM | 1 |
| Choi, YK | 1 |
| Lee, SJ | 1 |
| Ham, HJ | 1 |
| Kim, BG | 1 |
| Park, KG | 1 |
| Park, SY | 2 |
| Lee, CH | 1 |
| Choi, CS | 2 |
| Park, TS | 1 |
| Lee, WN | 1 |
| Harris, RA | 1 |
| Lee, IK | 1 |
| Cho, J | 1 |
| Zhang, Y | 1 |
| Joseph, AM | 1 |
| Han, C | 1 |
| Park, HJ | 1 |
| Kalavalapalli, S | 1 |
| Chun, SK | 1 |
| Morgan, D | 1 |
| Kim, JS | 1 |
| Someya, S | 1 |
| Mathews, CE | 1 |
| Lee, YJ | 1 |
| Wohlgemuth, SE | 1 |
| Sunny, NE | 1 |
| Lee, HY | 1 |
| Shiratsuchi, T | 1 |
| Oh, SP | 1 |
| Terada, N | 1 |
| Nomura, M | 1 |
| Ishii, H | 1 |
| Kawakami, A | 1 |
| Yoshida, M | 1 |
| HARTMANN, F | 1 |
| SCHULTE, G | 1 |
| Maddaiah, VT | 1 |
| Kumbar, U | 1 |
| Callaghan, R | 1 |
| Desmond, PV | 1 |
| Mashford, ML | 1 |
12 other studies available for pyruvic acid and Liver Steatosis
| Article | Year |
|---|---|
Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain.
Topics: Adaptor Proteins, Signal Transducing; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; En | 2019 |
Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis.
Topics: Animals; Cholesterol; Citrate (si)-Synthase; Diet; Fatty Liver; Lipid Metabolism; Liver; Male; Mitoc | 2017 |
Salsalate Activates Skeletal Muscle Thermogenesis and Protects Mice from High-Fat Diet Induced Metabolic Dysfunction.
Topics: Adipose Tissue, White; Animals; Body Weight; Cell Line; Diabetes Mellitus, Type 2; Diet, High-Fat; E | 2017 |
Cafeteria Diet Feeding in Young Rats Leads to Hepatic Steatosis and Increased Gluconeogenesis under Fatty Acids and Glucagon Influence.
Topics: Animals; Diet; Energy Intake; Fatty Acids; Fatty Liver; Feeding Behavior; Glucagon; Gluconeogenesis; | 2018 |
Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Azetidines; Azo Compounds; Blotting, Western; | 2013 |
Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function.
Topics: Animals; Blotting, Western; Body Composition; Ceramides; Diet, Western; Dipeptidyl-Peptidase IV Inhi | 2015 |
Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis.
Topics: Animals; Citric Acid Cycle; Diet, High-Fat; Fatty Liver; Glucose; Insulin Resistance; Lipogenesis; L | 2016 |
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance.
Topics: Adenine Nucleotide Translocator 2; Adenosine Triphosphate; Animals; Atractyloside; Diet, High-Fat; D | 2017 |
Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance.
Topics: Animals; Anticholesteremic Agents; Azetidines; Blotting, Western; Cells, Cultured; Cholesterol; DNA | 2009 |
[The lipotropic effect of pyruvic acid in experimental fatty liver].
Topics: Fatty Liver; Lipotropic Agents; Liver Diseases; Pyruvates; Pyruvic Acid | 1959 |
Ammonium chloride inhibits pyruvate oxidation in rat liver mitochondria: a possible cause of fatty liver in Reye's syndrome and urea cycle defects.
Topics: Adenosine Diphosphate; Ammonium Chloride; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; | 1994 |
The effect of a nutritional model of chronic liver injury on the hepatic glucuronidation of morphine in rats.
Topics: Animals; Body Weight; Choline Deficiency; Chromatography, High Pressure Liquid; Fatty Liver; Glucuro | 1993 |