pyruvic acid has been researched along with Leukemia in 7 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, colorectal cancer cells can effectively shift to FAO to survive both glucose restriction and increases in oxidative stress at the expense of decreasing anabolism." | 2.66 | The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival. ( De Oliveira, MP; Liesa, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| De Oliveira, MP | 1 |
| Liesa, M | 1 |
| Jun, S | 1 |
| Mahesula, S | 1 |
| Mathews, TP | 1 |
| Martin-Sandoval, MS | 1 |
| Zhao, Z | 1 |
| Piskounova, E | 1 |
| Agathocleous, M | 1 |
| Cipolleschi, MG | 1 |
| Marzi, I | 1 |
| Santini, R | 1 |
| Fredducci, D | 1 |
| Vinci, MC | 1 |
| D'Amico, M | 1 |
| Rovida, E | 1 |
| Stivarou, T | 1 |
| Torre, E | 1 |
| Dello Sbarba, P | 1 |
| Stecca, B | 1 |
| Olivotto, M | 1 |
| TSIRIMBAS, A | 1 |
| STICH, W | 1 |
| ZAMFIRESCU-GHEORGHIU, M | 1 |
| PETRESCU, M | 1 |
| GROZEA, P | 1 |
| GOCIU, M | 1 |
| SIGHETEA, E | 1 |
| CIOBANU, F | 1 |
| DEPASQUALE, C | 1 |
| RONCHI, F | 1 |
| MENGHINI, G | 1 |
| SANTAGATI, U | 1 |
| BOLDRINI, R | 1 |
1 review available for pyruvic acid and Leukemia
| Article | Year |
|---|---|
The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival.
Topics: Adipose Tissue; Animals; Cell Proliferation; Cell Survival; Fatty Acids; Glucose; Glycolysis; Humans | 2020 |
6 other studies available for pyruvic acid and Leukemia
| Article | Year |
|---|---|
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage.
Topics: Cell Lineage; Citric Acid Cycle; Humans; Leukemia; Oxidoreductases; Pyruvate Dehydrogenase Complex; | 2021 |
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Ac | 2014 |
[On pyruvic acid in blood and serum in human leukemias].
Topics: Leukemia; Pyruvates; Pyruvic Acid | 1961 |
[Contribution to the study of serum pyruvic acid in various malignant blood diseases].
Topics: Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma | 1962 |
[SOME DISORDERS OF CELL METABOLISM IN SYSTEMIC HISTIOCYTIC SARCOMATOSIS. II. THE PYRUVATE AND ALPHA-KETOGLUTARATE CONTENT OF NORMAL AND LEUKEMIC LEUKOCYTES].
Topics: Blood Chemical Analysis; Ketoglutaric Acids; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukoc | 1963 |
[Behavior of sugar, pyruvic acid and lactic acid in blood in lymphadenosis and chronic myeloid leukemia].
Topics: Blood Glucose; Humans; Lactic Acid; Leukemia; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BC | 1955 |